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Protein Ontology report - E3 ubiquitin-protein ligase pellino homolog 3
PR:000012540 - http://purl.obolibrary.org/obo/PR_000012540
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000012540   
  PRO nameE3 ubiquitin-protein ligase pellino homolog 3 
  Synonyms
PRO-Short-label: EXACT:PELI3
Other: EXACT:pellino 3 | pellino-3 | RING-type E3 ubiquitin transferase pellino homolog 3
  Definition"A protein pellino that is a translation product of the human PELI3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000003140 protein pellino
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012540
E3 ubiquitin-protein ligase pellino homolog 3
PELI3
"A protein pellino that is a translation product of the human PELI3 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q8BXR6
E3 ubiquitin-protein ligase pellino homolog 3 (mouse)
mPELI3
"An E3 ubiquitin-protein ligase pellino homolog 3 that is encoded in the genome of mouse." [OMA:Q8BXR6, PRO:CNA]

organism-sequence


PR:Q8BXR6-1
E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (mouse)
mPELI3/iso:2
"An E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PRO:CNA]

organism-gene


PR:Q8N2H9
E3 ubiquitin-protein ligase pellino homolog 3 (human)
hPELI3
"An E3 ubiquitin-protein ligase pellino homolog 3 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:Q8N2H9-1
E3 ubiquitin-protein ligase pellino homolog 3 isoform 1 (human)
hPELI3/iso:1
"An E3 ubiquitin-protein ligase pellino homolog 3 isoform 1 that is encoded in the genome of human." [PMID:12874243, PRO:CNA]

organism-sequence


PR:Q8N2H9-2
E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (human)
hPELI3/iso:2
"An E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 that is encoded in the genome of human." [PMID:12874243, PRO:CNA]
Yes
organism-sequence


PR:Q8N2H9-3
E3 ubiquitin-protein ligase pellino homolog 3 isoform h3 (human)
hPELI3/iso:h3
"An E3 ubiquitin-protein ligase pellino homolog 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N2H9-3." [PRO:DNx, UniProtKB:Q8N2H9]

organism-sequence


PR:Q8N2H9-4
E3 ubiquitin-protein ligase pellino homolog 3 isoform h4 (human)
hPELI3/iso:h4
"An E3 ubiquitin-protein ligase pellino homolog 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N2H9-4." [PRO:DNx, UniProtKB:Q8N2H9]

organism-modification


PR:000048742
E3 ubiquitin-protein ligase pellino homolog 3 phosphorylated form (human)
hPELI3/PhosRes+
"An E3 ubiquitin-protein ligase pellino homolog 3 (human) that includes at least one phosphorylated residue. UniProtKB:Q8N2H9, MOD:00696." [PRO:DNx, Reactome:R-HSA-450806]

sequence


PR:000027048
E3 ubiquitin-protein ligase pellino homolog 3 isoform 1
PELI3/iso:1
"An E3 ubiquitin-protein ligase pellino homolog 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N2H9-1 or a 1:1 ortholog thereof." [PMID:12874243, PRO:CNA]

organism-sequence


PR:Q8N2H9-1
E3 ubiquitin-protein ligase pellino homolog 3 isoform 1 (human)
hPELI3/iso:1
"An E3 ubiquitin-protein ligase pellino homolog 3 isoform 1 that is encoded in the genome of human." [PMID:12874243, PRO:CNA]

sequence


PR:000027050
E3 ubiquitin-protein ligase pellino homolog 3 isoform 2
PELI3/iso:2
"An E3 ubiquitin-protein ligase pellino homolog 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N2H9-2 or a 1:1 ortholog thereof." [PMID:12874243, PRO:CNA]

organism-sequence


PR:Q8BXR6-1
E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (mouse)
mPELI3/iso:2
"An E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PRO:CNA]

organism-sequence


PR:Q8N2H9-2
E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (human)
hPELI3/iso:2
"An E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 that is encoded in the genome of human." [PMID:12874243, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8N2H9-2 hPELI3/iso:2 acts_upstream_of_or_withinGO:0070534 protein K63-linked ubiquitination PMID:18326498
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway PMID:18326498