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Protein Ontology report - neuroendocrine convertase 2
PR:000012435 - http://purl.obolibrary.org/obo/PR_000012435
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012435   
  PRO nameneuroendocrine convertase 2 
  Synonyms
PRO-Short-label: EXACT:PCSK2
Gene-based: RELATED:Nec-2 | NEC2
Other: EXACT:KEX2-like endoprotease 2 | NEC 2 | prohormone convertase 2 | proprotein convertase 2
  Definition"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000003136 subtilisin/kexin-type proprotein convertase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2383
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012435

neuroendocrine convertase 2

PCSK2


"A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:G5ECN9

neuroendocrine convertase 2 (worm)

PCSK2 (worm)


"A neuroendocrine convertase 2 that is encoded in the genome of worm." [OMA:G5ECN9, PRO:DNx]


organism-sequence



PR:G5ECN9-1

neuroendocrine convertase 2 isoform a (worm)

PCSK2/iso:a (worm)


"A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-1." [PRO:DNx, UniProtKB:G5ECN9]


organism-sequence



PR:G5ECN9-3

neuroendocrine convertase 2 isoform c (worm)

PCSK2/iso:c (worm)


"A neuroendocrine convertase 2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:G5ECN9-3." [PRO:DNx, UniProtKB:G5ECN9]


organism-gene



PR:P16519

neuroendocrine convertase 2 (human)

hPCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16519]


organism-sequence



PR:P16519-1

neuroendocrine convertase 2 isoform h1 (human)

hPCSK2/iso:h1


"A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-1." [PRO:DNx, UniProtKB:P16519]


organism-sequence



PR:P16519-2

neuroendocrine convertase 2 isoform h2 (human)

hPCSK2/iso:h2


"A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-2." [PRO:DNx, UniProtKB:P16519]


organism-sequence



PR:P16519-3

neuroendocrine convertase 2 isoform h3 (human)

hPCSK2/iso:h3


"A neuroendocrine convertase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16519-3." [PRO:DNx, UniProtKB:P16519]


organism-modification



PR:000073554

neuroendocrine convertase 2, mature form (human)

hPCSK2/mature


"A neuroendocrine convertase 2 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P16519-1, 110-638." [PRO:DNx, Reactome:R-HSA-265156]


organism-modification



PR:000083080

neuroendocrine convertase 2 deaminated 1 (human)

hPCSK2/Deam:1


"A neuroendocrine convertase 2 (human) that has been deaminated on the residue at the position equivalent to Asn-192 of the amino acid sequence represented by UniProtKB:P16519-1. Example: UniProtKB:P16519-1, Asn-192, MOD:00684." [IEDB_epitope:1625815, PRO:DNx]


organism-gene



PR:P21661

neuroendocrine convertase 2 (mouse)

mPCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of mouse." [OMA:P21661, PRO:DNx]


organism-sequence



PR:P21661-1

neuroendocrine convertase 2 isoform 1 (mouse)

mPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P28841

neuroendocrine convertase 2 (rat)

rPCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of rat." [OMA:P28841, PRO:DNx]


organism-sequence



PR:P28841-1

neuroendocrine convertase 2 isoform 1 (rat)

rPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000058870

neuroendocrine convertase 2 N-glycosylated 1 (rat)

rPCSK2/NGlyco:1


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G09775CH. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G09775CH." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058871

neuroendocrine convertase 2 N-glycosylated 2 (rat)

rPCSK2/NGlyco:2


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G31852PQ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058872

neuroendocrine convertase 2 N-glycosylated 3 (rat)

rPCSK2/NGlyco:3


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G37135JQ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G37135JQ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058873

neuroendocrine convertase 2 N-glycosylated 4 (rat)

rPCSK2/NGlyco:4


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G41247ZX." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058874

neuroendocrine convertase 2 N-glycosylated 5 (rat)

rPCSK2/NGlyco:5


"A neuroendocrine convertase 2 (rat) that has been N-glycosylated at the residue equivalent to Asn-523 of the amino acid sequence represented by UniProtKB:P28841-1, in which the glycan structure is represented by GlyTouCan:G80966KZ. Example: UniProtKB:P28841-1, Asn-523, MOD:00160~GNO:G80966KZ." [GlyGen:P28841-1, PMID:24090084, PRO:DNx]


organism-gene



PR:Q9VBC7

neuroendocrine convertase 2 (fruit fly)

fly-PCSK2


"A neuroendocrine convertase 2 that is encoded in the genome of fruit fly." [OMA:Q9VBC7, PRO:DNx]


sequence



PR:000039057

neuroendocrine convertase 2 isoform 1

PCSK2/iso:1


"A neuroendocrine convertase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21661-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P21661-1

neuroendocrine convertase 2 isoform 1 (mouse)

mPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P28841-1

neuroendocrine convertase 2 isoform 1 (rat)

rPCSK2/iso:1


"A neuroendocrine convertase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]