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Protein Ontology report - proliferating cell nuclear antigen
PR:000012421 - http://purl.obolibrary.org/obo/PR_000012421
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000012421   
  PRO nameproliferating cell nuclear antigen 
  Synonyms
PRO-Short-label: EXACT:PCNA
Other: EXACT:cyclin
  Definition"A protein that is a translation product of the human PCNA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 10                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification3                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012421

proliferating cell nuclear antigen

PCNA


"A protein that is a translation product of the human PCNA gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O02115

proliferating cell nuclear antigen (worm)

PCNA (worm)


"A proliferating cell nuclear antigen that is encoded in the genome of worm." [OMA:O02115, PRO:DNx]


organism-gene



PR:P04961

proliferating cell nuclear antigen (rat)

rPCNA


"A proliferating cell nuclear antigen that is encoded in the genome of rat." [OMA:P04961, PRO:DNx]


organism-gene



PR:P12004

proliferating cell nuclear antigen (human)

hPCNA


"A proliferating cell nuclear antigen that is encoded in the genome of human." [PRO:DNx]


Yes
organism-modification



PR:000048707

proliferating cell nuclear antigen ubiquitinated 1 (human)

hPCNA/Ubiq:1


"A proliferating cell nuclear antigen (human) that has been ubiquitinated on the residue at the position equivalent to Lys-164 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Lys-164, MOD:01148." [PRO:DNx, Reactome:R-HSA-5651986]


organism-modification



PR:000064815

proliferating cell nuclear antigen sumoylated 1 (human)

hPCNA/Sumo:1


"A proliferating cell nuclear antigen (human) that has been sumoylated on the residues at the positions equivalent to Lys-164 and Lys-254 of the amino acid sequence represented by UniProtKB:P12004 and that includes at least one additional sumoylated lysine. UniProtKB:P12004, Lys-164/Lys-254, MOD:01149|MOD:01149." [PRO:DNx, Reactome:R-HSA-4615861]


organism-modification



PR:000066855

proliferating cell nuclear antigen cysteinylated 1 (human)

hPCNA/Cyst:1


"A proliferating cell nuclear antigen (human) that has been cysteinylated on the residue at the position equivalent to Cys-81 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Cys-81, MOD:00765." [IEDB_epitope:1055558, PRO:DNx]


organism-modification



PR:000068885

proliferating cell nuclear antigen methylated 1 (human)

hPCNA/Me:1


"A proliferating cell nuclear antigen (human) that has been methylated on the residue at the position equivalent to Asp-243 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Asp-243, MOD:00887." [IEDB_epitope:1318283, PRO:DNx]


organism-modification



PR:000070972

proliferating cell nuclear antigen deaminated 1 (human)

hPCNA/Deam:1


"A proliferating cell nuclear antigen (human) that has been deaminated on the residue at the position equivalent to Asn-177 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Asn-177, MOD:00684." [IEDB_epitope:1979858, PRO:DNx]


organism-modification



PR:000073020

proliferating cell nuclear antigen acetylated 1 (human)

hPCNA/Ac:1


"A proliferating cell nuclear antigen (human) that has been acetylated on the residue at the position equivalent to Lys-240 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Lys-240, MOD:00723." [IEDB_epitope:1319518, PRO:DNx]


organism-modification



PR:000082820

proliferating cell nuclear antigen methylated 2 (human)

hPCNA/Me:2


"A proliferating cell nuclear antigen (human) that has been methylated on the residue at the position equivalent to Cys-135 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Cys-135, MOD:00660." [IEDB_epitope:1037986, PRO:DNx]


organism-modification



PR:000083669

proliferating cell nuclear antigen deaminated 2 (human)

hPCNA/Deam:2


"A proliferating cell nuclear antigen (human) that has been deaminated on the residue at the position equivalent to Gln-125 of the amino acid sequence represented by UniProtKB:P12004. UniProtKB:P12004, Gln-125, MOD:00685." [IEDB_epitope:774206, PRO:DNx]


organism-gene



PR:P15873

proliferating cell nuclear antigen (yeast)

yPCNA


"A proliferating cell nuclear antigen that is encoded in the genome of yeast." [OMA:P15873, PRO:DNx]


organism-gene



PR:P17917

proliferating cell nuclear antigen (fruit fly)

fly-PCNA


"A proliferating cell nuclear antigen that is encoded in the genome of fruit fly." [OMA:P17917, PRO:DNx]


organism-gene



PR:P17918

proliferating cell nuclear antigen (mouse)

mPCNA


"A proliferating cell nuclear antigen that is encoded in the genome of mouse." [OMA:P17918, PRO:DNx]


organism-gene



PR:Q03392

proliferating cell nuclear antigen (Schizosaccharomyces pombe 972h-)

Spom972h-PCNA


"A proliferating cell nuclear antigen that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q03392, PRO:DNx]


organism-gene



PR:Q54K47

proliferating cell nuclear antigen (Dictyostelium discoideum)

Dicty-PCNA


"A proliferating cell nuclear antigen that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54K47, PRO:DNx]


organism-gene



PR:Q9DEA3

proliferating cell nuclear antigen (chicken)

chick-PCNA


"A proliferating cell nuclear antigen that is encoded in the genome of chicken." [OMA:Q9DEA3, PRO:DNx]


organism-gene



PR:Q9PTP1

proliferating cell nuclear antigen (zebrafish)

z-PCNA


"A proliferating cell nuclear antigen that is encoded in the genome of zebrafish." [OMA:Q9PTP1, PRO:DNx]


modification



PR:000044773

proliferating cell nuclear antigen ubiquitinated 1

PCNA/Ubiq:1


"A proliferating cell nuclear antigen that has been post-translationally modified to include ubiquitin crosslinked at the Lys residue equivalent to Lys-164 of the amino acid sequence represented by UniProtKB:P12004. Example: UniProtKB:P12004, Lys-164, MOD:01148." [PMID:21461937, PRO:DAN]


modification



PR:000044774

proliferating cell nuclear antigen monoubiquitinated 1

PCNA/MonoUbiq:1


"A proliferating cell nuclear antigen ubiquitinated 1 that is monoubiquitinated at the Lys residue equivalent to Lys-164 of the amino acid sequence represented by UniProtKB:P12004. Example: UniProtKB:P12004, Lys-164, PR:000044771." [PMID:21461937, PRO:DAN]


organism-modification



PR:000044777

proliferating cell nuclear antigen monoubiquitinated 1 (Schizosaccharomyces pombe)

Spom-PCNA/MonoUbiq:1


"A proliferating cell nuclear antigen monoubiquitinated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q03392, Lys-164, PR:000044771." [PMID:16641370, PomBase:MAH, PRO:DAN]


modification



PR:000044775

proliferating cell nuclear antigen K63-polyubiquitinated 1

PCNA/K63polyUbiq:1


"A proliferating cell nuclear antigen ubiquitinated 1 that is K63-polyubiquitinated at the Lys residue equivalent to Lys-164 of the amino acid sequence represented by UniProtKB:P12004. Example: UniProtKB:P12004, Lys-164, PR:000044772." [PMID:21461937, PRO:DAN]


organism-modification



PR:000044778

proliferating cell nuclear antigen K63-polyubiquitinated 1 (Schizosaccharomyces pombe)

Spom-PCNA/K63polyUbiq:1


"A proliferating cell nuclear antigen K63-polyubiquitinated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q03392, Lys-164, PR:000044772." [PMID:16641370, PomBase:MAH, PRO:DAN]


organism-modification



PR:000044776

proliferating cell nuclear antigen ubiquitinated 1 (Schizosaccharomyces pombe)

Spom-PCNA/Ubiq:1


"A proliferating cell nuclear antigen ubiquitinated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q03392, Lys-164, MOD:01148." [PMID:16641370, PomBase:MAH, PRO:DAN]


organism-modification



PR:000044777

proliferating cell nuclear antigen monoubiquitinated 1 (Schizosaccharomyces pombe)

Spom-PCNA/MonoUbiq:1


"A proliferating cell nuclear antigen monoubiquitinated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q03392, Lys-164, PR:000044771." [PMID:16641370, PomBase:MAH, PRO:DAN]


organism-modification



PR:000044778

proliferating cell nuclear antigen K63-polyubiquitinated 1 (Schizosaccharomyces pombe)

Spom-PCNA/K63polyUbiq:1


"A proliferating cell nuclear antigen K63-polyubiquitinated 1 in Schizosaccharomyces pombe. Example: UniProtKB:Q03392, Lys-164, PR:000044772." [PMID:16641370, PomBase:MAH, PRO:DAN]


organism-modification



PR:000049732

proliferating cell nuclear antigen K63-diubiquitinated 1 (Schizosaccharomyces pombe)

Spom-PCNA/K63diUbiq:1


"A proliferating cell nuclear antigen ubiquitinated 1 (Schizosaccharomyces pombe) that has K63-linked Ub-Ub at position Lys-164 of the amino acid sequence represented by UniProtKB:Q03392. Example: UniProtKB:Q03392, Lys-164, PR:000049733." [PMID:27151298, PomBase:MAH, PRO:CNA]


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PCNA forms found in complexes   

PCNA Component
Complexes
PR:P12004 hPCNA PR:000026440 PCNA complex (human)
PR:000037517 DNMT1:PCNA:UHRF1 complex (human)