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Protein Ontology report - poly [ADP-ribose] polymerase 1
PR:000012289 - http://purl.obolibrary.org/obo/PR_000012289
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012289   
  PRO namepoly [ADP-ribose] polymerase 1 
  Synonyms
PRO-Short-label: EXACT:PARP1
Gene-based: RELATED:Adprp | ADPRT | Adprt1 | PPOL
Other: EXACT:ADP-ribosyltransferase diphtheria toxin-like 1 | ADPRT 1 | ARTD1 | DNA ADP-ribosyltransferase PARP1 | msPARP | NAD(+) ADP-ribosyltransferase 1 | PARP-1 | poly[ADP-ribose] synthase 1 | poly[ADP-ribose] synthetase 1 | protein poly-ADP-ribosyltransferase PARP1
  Definition"A protein that is a translation product of the human PARP1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 8                                        
         Sequence0                                                  Organism-Sequence 7                                        
         Modification1                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2771
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012289
poly [ADP-ribose] polymerase 1
PARP1
"A protein that is a translation product of the human PARP1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P09874
poly [ADP-ribose] polymerase 1 (human)
hPARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09874]

organism-modification


PR:000045662
poly [ADP-ribose] polymerase 1 phosphorylated 1 (human)
hPARP1/Phos:1
"A poly [ADP-ribose] polymerase 1 (human) that has been phosphorylated at Ser-177. UniProtKB:P09874, Ser-177, MOD:00046." [iPTMnet:P09874, PMID:23382195]

organism-modification


PR:000048695
poly [ADP-ribose] polymerase 1, initiator methionine removed form (human)
hPARP1/InitMet-
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed. UniProtKB:P09874, 2-1014." [PRO:DNx, Reactome:R-HSA-201568]

organism-modification


PR:000048696
poly [ADP-ribose] polymerase 1, initiator methionine removed ADP-ribosylglutamate form (human)
hPARP1/InitMet-/ADPribGlu+
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed and that includes at least one ADP-ribosylated glutamic acid. UniProtKB:P09874, 2-1014, MOD:00300." [PRO:DNx, Reactome:R-HSA-5651713]

organism-modification


PR:000064801
poly [ADP-ribose] polymerase 1, initiator methionine removed sumoylated 1 (human)
hPARP1/InitMet-/Sumo:1
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed and that has been sumoylated on the residues at the positions equivalent to Lys-203 and Lys-486 of the amino acid sequence represented by UniProtKB:P09874. UniProtKB:P09874, 2-1014, Lys-203/Lys-486, MOD:01149." [PRO:DNx, Reactome:R-HSA-4551617, Reactome:R-HSA-4551686]

organism-modification


PR:000048696
poly [ADP-ribose] polymerase 1, initiator methionine removed ADP-ribosylglutamate form (human)
hPARP1/InitMet-/ADPribGlu+
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed and that includes at least one ADP-ribosylated glutamic acid. UniProtKB:P09874, 2-1014, MOD:00300." [PRO:DNx, Reactome:R-HSA-5651713]

organism-modification


PR:000067304
poly [ADP-ribose] polymerase 1 deaminated 1 (human)
hPARP1/Deam:1
"A poly [ADP-ribose] polymerase 1 (human) that has been deaminated on the residue at the position equivalent to Asn-754 of the amino acid sequence represented by UniProtKB:P09874. UniProtKB:P09874, Asn-754, MOD:00684." [IEDB_epitope:1989851, PRO:DNx]

organism-modification


PR:000067499
poly [ADP-ribose] polymerase 1 phosphorylated 2 (human)
hPARP1/Phos:2
"A poly [ADP-ribose] polymerase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-519 of the amino acid sequence represented by UniProtKB:P09874. UniProtKB:P09874, Ser-519, MOD:00046." [IEDB_epitope:2147178, PRO:DNx]

organism-modification


PR:000080715
poly [ADP-ribose] polymerase 1 deaminated 2 (human)
hPARP1/Deam:2
"A poly [ADP-ribose] polymerase 1 (human) that has been deaminated on the residue at the position equivalent to Gln-718 of the amino acid sequence represented by UniProtKB:P09874. UniProtKB:P09874, Gln-718, MOD:00685." [IEDB_epitope:1345165, IEDB_epitope:1357040, PRO:DNx]

organism-gene


PR:P11103
poly [ADP-ribose] polymerase 1 (mouse)
mPARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of mouse." [OMA:P11103, PRO:DNx]

organism-sequence


PR:P11103-1
poly [ADP-ribose] polymerase 1 isoform m1 (mouse)
mPARP1/iso:m1
"A poly [ADP-ribose] polymerase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11103-1." [PRO:DNx, UniProtKB:P11103]

organism-sequence


PR:P11103-2
poly [ADP-ribose] polymerase 1 isoform m2 (mouse)
mPARP1/iso:m2
"A poly [ADP-ribose] polymerase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11103-2." [PRO:DNx, UniProtKB:P11103]

organism-gene


PR:P18493
poly [ADP-ribose] polymerase 1 (cow)
cow-PARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of cow." [OMA:P18493, PRO:DNx]

organism-gene


PR:P27008
poly [ADP-ribose] polymerase 1 (rat)
rPARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of rat." [OMA:P27008, PRO:DNx]

organism-gene


PR:P35875
poly [ADP-ribose] polymerase (fruit fly)
fly-PARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of fruit fly." [OMA:P35875, PRO:DNx]

organism-sequence


PR:P35875-1
poly [ADP-ribose] polymerase isoform II (fruit fly)
fly-PARP1/iso:II
"A poly [ADP-ribose] polymerase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35875-1." [PRO:DNx, UniProtKB:P35875]

organism-sequence


PR:P35875-2
poly [ADP-ribose] polymerase isoform I (fruit fly)
fly-PARP1/iso:I
"A poly [ADP-ribose] polymerase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35875-2." [PRO:DNx, UniProtKB:P35875]

organism-sequence


PR:P35875-3
poly [ADP-ribose] polymerase isoform E (fruit fly)
fly-PARP1/iso:E
"A poly [ADP-ribose] polymerase (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35875-3." [PRO:DNx, UniProtKB:P35875]

organism-gene


PR:Q5RHR0
poly [ADP-ribose] polymerase 1 (zebrafish)
z-PARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of zebrafish." [OMA:Q5RHR0, PRO:DNx]

organism-sequence


PR:Q5RHR0-1
poly [ADP-ribose] polymerase 1 isoform 1 (zebrafish)
z-PARP1/iso:1
"A poly [ADP-ribose] polymerase 1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5RHR0-1." [PRO:DNx, UniProtKB:Q5RHR0]

organism-sequence


PR:Q5RHR0-2
poly [ADP-ribose] polymerase 1 isoform 2 (zebrafish)
z-PARP1/iso:2
"A poly [ADP-ribose] polymerase 1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5RHR0-2." [PRO:DNx, UniProtKB:Q5RHR0]

organism-gene


PR:Q9N4H4
poly [ADP-ribose] polymerase 1 (worm)
PARP1 (worm)
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of worm." [OMA:Q9N4H4, PRO:DNx]

organism-gene


PR:Q9ZP54
poly [ADP-ribose] polymerase 1 (Arabidopsis thaliana)
At-PARP1
"A poly [ADP-ribose] polymerase 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9ZP54, PRO:DNx]

modification


PR:000020872
poly [ADP-ribose] polymerase 1, initiator methionine removed form
PARP1/InitMet-
"A poly [ADP-ribose] polymerase 1 that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000048695
poly [ADP-ribose] polymerase 1, initiator methionine removed form (human)
hPARP1/InitMet-
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed. UniProtKB:P09874, 2-1014." [PRO:DNx, Reactome:R-HSA-201568]

organism-modification


PR:000048696
poly [ADP-ribose] polymerase 1, initiator methionine removed ADP-ribosylglutamate form (human)
hPARP1/InitMet-/ADPribGlu+
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed and that includes at least one ADP-ribosylated glutamic acid. UniProtKB:P09874, 2-1014, MOD:00300." [PRO:DNx, Reactome:R-HSA-5651713]

organism-modification


PR:000064801
poly [ADP-ribose] polymerase 1, initiator methionine removed sumoylated 1 (human)
hPARP1/InitMet-/Sumo:1
"A poly [ADP-ribose] polymerase 1 (human) that has had the initiator methionine removed and that has been sumoylated on the residues at the positions equivalent to Lys-203 and Lys-486 of the amino acid sequence represented by UniProtKB:P09874. UniProtKB:P09874, 2-1014, Lys-203/Lys-486, MOD:01149." [PRO:DNx, Reactome:R-HSA-4551617, Reactome:R-HSA-4551686]