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Protein Ontology report - phenylalanine-4-hydroxylase
PR:000012234 - http://purl.obolibrary.org/obo/PR_000012234
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012234   
  PRO namephenylalanine-4-hydroxylase 
  Synonyms
PRO-Short-label: EXACT:PAH
Other: EXACT:Phe-4-monooxygenase
  Definition"A protein that is a translation product of the human PAH gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1240
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012234

phenylalanine-4-hydroxylase

PAH


"A protein that is a translation product of the human PAH gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P00439

phenylalanine-4-hydroxylase (human)

hPAH


"A phenylalanine-4-hydroxylase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00439]


organism-modification



PR:000045626

phenylalanine-4-hydroxylase phosphorylated 1 (human)

hPAH/Phos:1


"A phenylalanine-4-hydroxylase (human) that has been phosphorylated at Ser-16. UniProtKB:P00439, Ser-16, MOD:00046." [iPTMnet:P00439, PMID:12185072, PMID:20937381]


organism-modification



PR:000061611

phenylalanine-4-hydroxylase sequence variant S40L, initiator methionine removed form (human)

hPAH/var:S40L/InitMet-


"A phenylalanine-4-hydroxylase (human) that has a Leu residue at the position equivalent to Ser-40 of the amino acid sequence represented by UniProtKB:P00439 and that has had the initiator methionine removed. UniProtKB:P00439, 2-452, Ser-40, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-5649486]


organism-modification



PR:000065634

phenylalanine-4-hydroxylase methylated 1 (human)

hPAH/Me:1


"A phenylalanine-4-hydroxylase (human) that has been methylated on the residue at the position equivalent to Cys-445 of the amino acid sequence represented by UniProtKB:P00439. UniProtKB:P00439, Cys-445, MOD:00660." [IEDB_epitope:1015331, PRO:DNx]


organism-modification



PR:000085170

phenylalanine-4-hydroxylase methylated 2 (human)

hPAH/Me:2


"A phenylalanine-4-hydroxylase (human) that has been methylated on the residue at the position equivalent to Cys-265 of the amino acid sequence represented by UniProtKB:P00439. UniProtKB:P00439, Cys-265, MOD:00660." [IEDB_epitope:1057319, PRO:DNx]


organism-gene



PR:P04176

phenylalanine-4-hydroxylase (rat)

rPAH


"A phenylalanine-4-hydroxylase that is encoded in the genome of rat." [OMA:P04176, PRO:DNx]


organism-gene



PR:P16331

phenylalanine-4-hydroxylase (mouse)

mPAH


"A phenylalanine-4-hydroxylase that is encoded in the genome of mouse." [OMA:P16331, PRO:DNx]


organism-gene



PR:P17276

protein henna (fruit fly)

fly-PAH


"A phenylalanine-4-hydroxylase that is encoded in the genome of fruit fly." [OMA:P17276, PRO:DNx]


organism-gene



PR:P90925

phenylalanine-4-hydroxylase (worm)

PAH (worm)


"A phenylalanine-4-hydroxylase that is encoded in the genome of worm." [OMA:P90925, PRO:DNx]


organism-sequence



PR:P90925-1

phenylalanine-4-hydroxylase isoform a (worm)

PAH/iso:a (worm)


"A phenylalanine-4-hydroxylase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P90925-1." [PRO:DNx, UniProtKB:P90925]


organism-sequence



PR:P90925-2

phenylalanine-4-hydroxylase isoform b (worm)

PAH/iso:b (worm)


"A phenylalanine-4-hydroxylase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P90925-2." [PRO:DNx, UniProtKB:P90925]


organism-gene



PR:Q54XS1

phenylalanine-4-hydroxylase (Dictyostelium discoideum)

Dicty-PAH


"A phenylalanine-4-hydroxylase that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]


modification



PR:000020863

phenylalanine-4-hydroxylase, initiator methionine removed form

PAH/InitMet-


"A phenylalanine-4-hydroxylase that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000061611

phenylalanine-4-hydroxylase sequence variant S40L, initiator methionine removed form (human)

hPAH/var:S40L/InitMet-


"A phenylalanine-4-hydroxylase (human) that has a Leu residue at the position equivalent to Ser-40 of the amino acid sequence represented by UniProtKB:P00439 and that has had the initiator methionine removed. UniProtKB:P00439, 2-452, Ser-40, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-5649486]