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Protein Ontology report - glucocorticoid receptor
PR:000011406 - http://purl.obolibrary.org/obo/PR_000011406
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000011406   
  PRO nameglucocorticoid receptor 
  Synonyms
PRO-Short-label: EXACT:NR3C1
Gene-based: RELATED:GRL | Grl1
Other: EXACT:nuclear receptor subfamily 3 group C member 1
RELATED:GR
  Definition"A protein that is a translation product of the human NR3C1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 23                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:625
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000011406

glucocorticoid receptor

NR3C1


"A protein that is a translation product of the human NR3C1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P04150

glucocorticoid receptor (human)

hNR3C1


"A glucocorticoid receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-1

glucocorticoid receptor isoform Alpha (human)

hNR3C1/iso:Alpha


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-1." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-10

glucocorticoid receptor isoform h10 (human)

hNR3C1/iso:h10


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-10." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-11

glucocorticoid receptor isoform hAlpha-C1 (human)

hNR3C1/iso:hAlpha-C1


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-11." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-12

glucocorticoid receptor isoform hAlpha-C2 (human)

hNR3C1/iso:hAlpha-C2


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-12." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-13

glucocorticoid receptor isoform hAlpha-C3 (human)

hNR3C1/iso:hAlpha-C3


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-13." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-14

glucocorticoid receptor isoform hAlpha-D1 (human)

hNR3C1/iso:hAlpha-D1


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-14." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-15

glucocorticoid receptor isoform hAlpha-D2 (human)

hNR3C1/iso:hAlpha-D2


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-15." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-16

glucocorticoid receptor isoform hAlpha-D3 (human)

hNR3C1/iso:hAlpha-D3


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-16." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-2

glucocorticoid receptor isoform Beta (human)

hNR3C1/iso:Beta


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-2." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-3

glucocorticoid receptor isoform hAlpha-2 (human)

hNR3C1/iso:hAlpha-2


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-3." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-4

glucocorticoid receptor isoform GR-P (human)

hNR3C1/iso:GR-P


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-4." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-5

glucocorticoid receptor isoform GR-A alpha (human)

hNR3C1/iso:GR-A alpha


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-5." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-6

glucocorticoid receptor isoform hBeta-2 (human)

hNR3C1/iso:hBeta-2


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-6." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-7

glucocorticoid receptor isoform GR-A beta (human)

hNR3C1/iso:GR-A beta


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-7." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-8

glucocorticoid receptor isoform Alpha-B (human)

hNR3C1/iso:Alpha-B


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-8." [PRO:DNx, UniProtKB:P04150]


organism-sequence



PR:P04150-9

glucocorticoid receptor isoform Beta-B (human)

hNR3C1/iso:Beta-B


"A glucocorticoid receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04150-9." [PRO:DNx, UniProtKB:P04150]


organism-modification



PR:000045633

glucocorticoid receptor phosphorylated 1 (human)

hNR3C1/Phos:1


"A glucocorticoid receptor (human) that has been phosphorylated on the residue at the position equivalent to Ser-211 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Ser-211, MOD:00046." [iPTMnet:P04150, PMID:15817653]


organism-modification



PR:000064852

glucocorticoid receptor sumoylated 1 (human)

hNR3C1/Sumo:1


"A glucocorticoid receptor (human) that has been sumoylated on the residues at the positions equivalent to Lys-277 and Lys-293 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Lys-277/Lys-293, MOD:01149." [PRO:DNx, Reactome:R-HSA-4341106]


organism-modification



PR:000072281

glucocorticoid receptor methylated 1 (human)

hNR3C1/Me:1


"A glucocorticoid receptor (human) that has been methylated on the residue at the position equivalent to Cys-665 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Cys-665, MOD:00660." [IEDB_epitope:1061610, PRO:DNx]


organism-modification



PR:000073238

glucocorticoid receptor deaminated 1 (human)

hNR3C1/Deam:1


"A glucocorticoid receptor (human) that has been deaminated on the residue at the position equivalent to Asn-766 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Asn-766, MOD:00684." [IEDB_epitope:2000820, PRO:DNx]


organism-modification



PR:000073956

glucocorticoid receptor methylated 2 (human)

hNR3C1/Me:2


"A glucocorticoid receptor (human) that has been methylated on the residue at the position equivalent to Cys-441 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Cys-441, MOD:00660." [IEDB_epitope:1016569, PRO:DNx]


organism-modification



PR:000080881

glucocorticoid receptor methylated 3 (human)

hNR3C1/Me:3


"A glucocorticoid receptor (human) that has been methylated on the residue at the position equivalent to Cys-302 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Cys-302, MOD:00660." [IEDB_epitope:1004183, PRO:DNx]


organism-modification



PR:000085650

glucocorticoid receptor deaminated 2 (human)

hNR3C1/Deam:2


"A glucocorticoid receptor (human) that has been deaminated on the residue at the position equivalent to Asn-314 of the amino acid sequence represented by UniProtKB:P04150-1. Example: UniProtKB:P04150-1, Asn-314, MOD:00684." [IEDB_epitope:1981973, PRO:DNx]


organism-gene



PR:P06536

glucocorticoid receptor (rat)

rNR3C1


"A glucocorticoid receptor that is encoded in the genome of rat." [OMA:P06536, PRO:DNx]


organism-sequence



PR:P06536-1

glucocorticoid receptor isoform A (rat)

rNR3C1/iso:A


"A glucocorticoid receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06536-1." [PRO:DNx, UniProtKB:P06536]


organism-sequence



PR:P06536-2

glucocorticoid receptor isoform B (rat)

rNR3C1/iso:B


"A glucocorticoid receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06536-2." [PRO:DNx, UniProtKB:P06536]


organism-gene



PR:P06537

glucocorticoid receptor (mouse)

mNR3C1


"A glucocorticoid receptor that is encoded in the genome of mouse." [OMA:P06537, PRO:DNx]


organism-sequence



PR:P06537-1

glucocorticoid receptor isoform m1 (mouse)

mNR3C1/iso:m1


"A glucocorticoid receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06537-1." [PRO:DNx, UniProtKB:P06537]


organism-sequence



PR:P06537-2

glucocorticoid receptor isoform 2 (mouse)

mNR3C1/iso:2


"A glucocorticoid receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06537-2." [PRO:DNx, UniProtKB:P06537]

Yes

organism-sequence



PR:P06537-3

glucocorticoid receptor isoform m1-B (mouse)

mNR3C1/iso:m1-B


"A glucocorticoid receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06537-3." [PRO:DNx, UniProtKB:P06537]


organism-sequence



PR:P06537-4

glucocorticoid receptor isoform m2-B (mouse)

mNR3C1/iso:m2-B


"A glucocorticoid receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06537-4." [PRO:DNx, UniProtKB:P06537]


organism-sequence



PR:P06537-5

glucocorticoid receptor isoform m3 (mouse)

mNR3C1/iso:m3


"A glucocorticoid receptor (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06537-5." [PRO:DNx, UniProtKB:P06537]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P06537-2 mNR3C1/iso:2 acts_upstream_of_or_withinGO:2000323 negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway MGI_ref:5316956; PMID:20660300
located_inGO:0005634 nucleus MGI_ref:5316956; PMID:20660300
GO:0005737 cytoplasm MGI_ref:5316956; PMID:20660300