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Protein Ontology report - NPC intracellular cholesterol transporter 2
PR:000011357 - http://purl.obolibrary.org/obo/PR_000011357
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000011357   
  PRO nameNPC intracellular cholesterol transporter 2 
  Synonyms
PRO-Short-label: EXACT:NPC2
Gene-based: RELATED:HE1
Other: EXACT:E1 | epididymal secretory protein E1 | epididymis-specific protein 1 | Niemann Pick type C2 protein homolog | Niemann-Pick disease type C2 protein
  Definition"A protein that is a translation product of the human NPC2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000011357

NPC intracellular cholesterol transporter 2

NPC2


"A protein that is a translation product of the human NPC2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P61916

NPC intracellular cholesterol transporter 2 (human)

hNPC2


"An NPC intracellular cholesterol transporter 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P61916]


organism-sequence



PR:P61916-1

NPC intracellular cholesterol transporter 2 isoform h1 (human)

hNPC2/iso:h1


"An NPC intracellular cholesterol transporter 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61916-1." [PRO:DNx, UniProtKB:P61916]


organism-sequence



PR:P61916-2

NPC intracellular cholesterol transporter 2 isoform h2 (human)

hNPC2/iso:h2


"An NPC intracellular cholesterol transporter 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61916-2." [PRO:DNx, UniProtKB:P61916]


organism-modification



PR:000063513

NPC intracellular cholesterol transporter 2, signal peptide removed form (human)

hNPC2/SigPep-


"An NPC intracellular cholesterol transporter 2 (human) that has had the signal peptide removed. Example: UniProtKB:P61916-1, 20-151." [PRO:DNx, Reactome:R-HSA-6799163, Reactome:R-HSA-6806224, Reactome:R-HSA-8876488]


organism-modification



PR:000077256

NPC intracellular cholesterol transporter 2 glutathionylated 1 (human)

hNPC2/SGlt:1


"An NPC intracellular cholesterol transporter 2 (human) that has been glutathionylated on the residue at the position equivalent to Cys-99 of the amino acid sequence represented by UniProtKB:P61916-1. Example: UniProtKB:P61916-1, Cys-99, MOD:00234." [IEDB_epitope:422428, PRO:DNx]


organism-modification



PR:000078353

NPC intracellular cholesterol transporter 2 cysteinylated 1 (human)

hNPC2/Cyst:1


"An NPC intracellular cholesterol transporter 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-140 of the amino acid sequence represented by UniProtKB:P61916-1. Example: UniProtKB:P61916-1, Cys-140, MOD:00765." [IEDB_epitope:2126546, PRO:DNx]


organism-modification



PR:000078849

NPC intracellular cholesterol transporter 2 methylated 1 (human)

hNPC2/Me:1


"An NPC intracellular cholesterol transporter 2 (human) that has been methylated on the residue at the position equivalent to Cys-99 of the amino acid sequence represented by UniProtKB:P61916-1. Example: UniProtKB:P61916-1, Cys-99, MOD:00660." [IEDB_epitope:1048929, PRO:DNx]


organism-modification



PR:000080173

NPC intracellular cholesterol transporter 2 cysteinylated 2 (human)

hNPC2/Cyst:2


"An NPC intracellular cholesterol transporter 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-99 of the amino acid sequence represented by UniProtKB:P61916-1. Example: UniProtKB:P61916-1, Cys-99, MOD:00765." [IEDB_epitope:2117957, PRO:DNx]


organism-gene



PR:Q9DGJ3

NPC intracellular cholesterol transporter 2 (zebrafish)

z-NPC2


"An NPC intracellular cholesterol transporter 2 that is encoded in the genome of zebrafish." [PRO:DNx]


organism-gene



PR:Q9VQ62

NPC intracellular cholesterol transporter 2 homolog a (fruit fly)

fly-NPC2


"An NPC intracellular cholesterol transporter 2 that is encoded in the genome of fruit fly." [OMA:Q9VQ62, PRO:DNx]


organism-gene



PR:Q9Z0J0

NPC intracellular cholesterol transporter 2 (mouse)

mNPC2


"An NPC intracellular cholesterol transporter 2 that is encoded in the genome of mouse." [OMA:Q9Z0J0, PRO:DNx]