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Protein Ontology report - neurogenic locus notch homolog protein 2
PR:000011332 - http://purl.obolibrary.org/obo/PR_000011332
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000011332   
  PRO nameneurogenic locus notch homolog protein 2 
  Synonyms
PRO-Short-label: EXACT:NOTCH2
Other: EXACT:N2 | neurogenic locus notch protein 2 | notch 2 | notch B
  Definition"A NOTCH protein that is a translation product of the human NOTCH2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050044 NOTCH protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2859
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000011332
neurogenic locus notch homolog protein 2
NOTCH2
"A NOTCH protein that is a translation product of the human NOTCH2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O35516
neurogenic locus notch homolog protein 2 (mouse)
mNOTCH2
"A neurogenic locus notch homolog protein 2 that is encoded in the genome of mouse." [OMA:O35516, PRO:DAN]

organism-sequence


PR:O35516-1
neurogenic locus notch homolog protein 2 isoform m1 (mouse)
mNOTCH2/iso:m1
"A neurogenic locus notch homolog protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35516-1." [PRO:DNx, UniProtKB:O35516]

organism-sequence


PR:O35516-2
neurogenic locus notch homolog protein 2 isoform m2 (mouse)
mNOTCH2/iso:m2
"A neurogenic locus notch homolog protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35516-2." [PRO:DNx, UniProtKB:O35516]

organism-modification


PR:000077266
neurogenic locus notch homolog protein 2 deaminated 1 (mouse)
mNOTCH2/Deam:1
"A neurogenic locus notch homolog protein 2 (mouse) that has been deaminated on the residue at the position equivalent to Gln-2426 of the amino acid sequence represented by UniProtKB:O35516-1. Example: UniProtKB:O35516-1, Gln-2426, MOD:00685." [IEDB_epitope:2137457, IEDB_epitope:2137458, PRO:DNx]

organism-gene


PR:Q04721
neurogenic locus notch homolog protein 2 (human)
hNOTCH2
"A neurogenic locus notch homolog protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q04721]

organism-modification


PR:000056863
neurogenic locus notch homolog protein 2 O-glycosylated 1 (human)
hNOTCH2/OGlyco:1
"A neurogenic locus notch homolog protein 2 (human) that has been O-glycosylated at the residue equivalent to Ser-1419 of the amino acid sequence represented by UniProtKB:Q04721-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q04721-1, Ser-1419, MOD:00002~GNO:G43417UB." [GlyGen:Q04721-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000056864
neurogenic locus notch homolog protein 2 O-glycosylated 2 (human)
hNOTCH2/OGlyco:2
"A neurogenic locus notch homolog protein 2 (human) that has been O-glycosylated at the residue equivalent to Thr-1420 of the amino acid sequence represented by UniProtKB:Q04721-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q04721-1, Thr-1420, MOD:00005~GNO:G43417UB." [GlyGen:Q04721-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000061423
neurogenic locus notch homolog protein 2, signal peptide removed form (human)
hNOTCH2/SigPep-
"A neurogenic locus notch homolog protein 2 (human) that has had the signal peptide removed. UniProtKB:Q04721, 26-2471." [PRO:DNx, Reactome:R-HSA-157025]

organism-modification


PR:000061892
neurogenic locus notch homolog protein 2, signal peptide removed O-glycosylated 1 (human)
hNOTCH2/SigPep-/OGlyco:1
"A neurogenic locus notch homolog protein 2 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Thr-78, Thr-120, Thr-158, Thr-197, Thr-235, Thr-314, Thr-352, Thr-470, Thr-696, Thr-771, Thr-809, Ser-925, Thr-963, Thr-1001, Thr-1039, Thr-1077, Thr-1163, Thr-1201, and Thr-1318 of the amino acid sequence represented by UniProtKB:Q04721. UniProtKB:Q04721, 26-2471, Thr-78/Thr-120/Thr-158/Thr-197/Thr-235/Thr-314/Thr-352/Thr-470/Thr-696/Thr-771/Thr-809/Thr-963/Thr-1001/Thr-1039/Thr-1077/Thr-1163/Thr-1201/Thr-1318, MOD:00813|Ser-925, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467363]

organism-modification


PR:000085801
neurogenic locus notch homolog protein 2, signal peptide removed O-glycosylated 2 (human)
hNOTCH2/SigPep-/OGlyco:2
"A neurogenic locus notch homolog protein 2 (human) that has had the signal peptide removed and that has been O-glycosylated on the residues at the positions equivalent to Thr-78, Thr-120, Ser-150, Thr-158, Thr-197, Thr-235, Thr-314, Thr-352, Ser-381, Ser-462, Thr-470, Ser-500, Ser-538, Ser-613, Ser-651, Ser-688, Thr-696, Ser-726, Ser-763, Thr-771, Ser-801, Thr-809, Ser-879, Ser-925, Ser-955, Thr-963, Thr-1001, Ser-1031, Thr-1039, Thr-1077, Ser-1155, Thr-1163, Thr-1201, Ser-1270, and Thr-1318 of the amino acid sequence represented by UniProtKB:Q04721. UniProtKB:Q04721, 26-2471, Thr-78/Thr-120/Thr-158/Thr-197/Thr-235/Thr-314/Thr-352/Thr-470/Thr-696/Thr-771/Thr-809/Thr-963/Thr-1001/Thr-1039/Thr-1077/Thr-1163/Thr-1201/Thr-1318, MOD:00813|Ser-150/Ser-381/Ser-462/Ser-500/Ser-538/Ser-613/Ser-651/Ser-688/Ser-726/Ser-763/Ser-801/Ser-879/Ser-955/Ser-1031/Ser-1155/Ser-1270, MOD:00804|Ser-925, MOD:00812." [PRO:DNx, Reactome:R-HSA-1467379, Reactome:R-HSA-1472874]

organism-modification


PR:000074275
neurogenic locus notch homolog protein 2 deaminated 1 (human)
hNOTCH2/Deam:1
"A neurogenic locus notch homolog protein 2 (human) that has been deaminated on the residue at the position equivalent to Asn-1857 of the amino acid sequence represented by UniProtKB:Q04721. UniProtKB:Q04721, Asn-1857, MOD:00684." [IEDB_epitope:1314741, PRO:DNx]

organism-gene


PR:Q9QW30
neurogenic locus notch homolog protein 2 (rat)
rNOTCH2
"A neurogenic locus notch homolog protein 2 that is encoded in the genome of rat." [PRO:DAN]

modification


PR:000020764
neurogenic locus notch homolog protein 2 proteolytic cleavage product
NOTCH2/ClvPrd
"A neurogenic locus notch homolog protein 2 that has been processed by proteolytic cleavage." [PRO:DNx]