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Protein Ontology report - neuroepithelial cell-transforming gene 1 protein
PR:000011142 - http://purl.obolibrary.org/obo/PR_000011142
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000011142   
  PRO nameneuroepithelial cell-transforming gene 1 protein 
  Synonyms
PRO-Short-label: EXACT:NET1
Gene-based: RELATED:ARHGEF8
Other: EXACT:proto-oncogene p65 Net1 | rho guanine nucleotide exchange factor 8
  Definition"A protein that is a translation product of the human NET1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000011142

neuroepithelial cell-transforming gene 1 protein

NET1


"A protein that is a translation product of the human NET1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q7Z628

neuroepithelial cell-transforming gene 1 protein (human)

hNET1


"A neuroepithelial cell-transforming gene 1 protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q7Z628]


organism-sequence



PR:Q7Z628-1

neuroepithelial cell-transforming gene 1 protein isoform 1 (human)

hNET1/iso:1


"A neuroepithelial cell-transforming gene 1 protein isoform 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z628]


organism-sequence



PR:Q7Z628-2

neuroepithelial cell-transforming gene 1 protein isoform 2 (human)

hNET1/iso:2


"A neuroepithelial cell-transforming gene 1 protein isoform 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z628]


organism-modification



PR:000084291

neuroepithelial cell-transforming gene 1 protein phosphorylated 1 (human)

hNET1/Phos:1


"A neuroepithelial cell-transforming gene 1 protein (human) that has been phosphorylated on the residue at the position equivalent to Thr-329 of the amino acid sequence represented by UniProtKB:Q7Z628-1. Example: UniProtKB:Q7Z628-1, Thr-329, MOD:00047." [IEDB_epitope:2147696, PRO:DNx]


organism-gene



PR:Q9Z206

neuroepithelial cell-transforming gene 1 protein (mouse)

mNET1


"A neuroepithelial cell-transforming gene 1 protein that is encoded in the genome of mouse." [OMA:Q9Z206, PRO:DNx]


organism-sequence



PR:Q9Z206-1

neuroepithelial cell-transforming gene 1 protein isoform 1 (mouse)

mNET1/iso:1


"A neuroepithelial cell-transforming gene 1 protein isoform 1 that is encoded in the genome of mouse." [PMID:9670022, PRO:HJD]

Yes

organism-sequence



PR:Q9Z206-2

neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse)

mNET1/iso:2


"A neuroepithelial cell-transforming gene 1 protein isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PMID:23184663, PRO:HJD]

Yes

sequence



PR:000037449

neuroepithelial cell-transforming gene 1 protein isoform 1

NET1/iso:1


"A neuroepithelial cell-transforming gene 1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z206-1 or a 1:1 ortholog thereof." [PMID:9670022, PRO:HJD]


organism-sequence



PR:Q7Z628-1

neuroepithelial cell-transforming gene 1 protein isoform 1 (human)

hNET1/iso:1


"A neuroepithelial cell-transforming gene 1 protein isoform 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z628]


organism-sequence



PR:Q9Z206-1

neuroepithelial cell-transforming gene 1 protein isoform 1 (mouse)

mNET1/iso:1


"A neuroepithelial cell-transforming gene 1 protein isoform 1 that is encoded in the genome of mouse." [PMID:9670022, PRO:HJD]

Yes

sequence



PR:000037450

neuroepithelial cell-transforming gene 1 protein isoform 2

NET1/iso:2


"A neuroepithelial cell-transforming gene 1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z206-2 or a 1:1 ortholog thereof. This isoform differs from isoform 1 in the N-terminal region and is missing the nuclear localization signal." [PMID:15489334, PMID:23184663, PRO:HJD]


organism-sequence



PR:Q7Z628-2

neuroepithelial cell-transforming gene 1 protein isoform 2 (human)

hNET1/iso:2


"A neuroepithelial cell-transforming gene 1 protein isoform 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q7Z628]


organism-sequence



PR:Q9Z206-2

neuroepithelial cell-transforming gene 1 protein isoform 2 (mouse)

mNET1/iso:2


"A neuroepithelial cell-transforming gene 1 protein isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PMID:23184663, PRO:HJD]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9Z206-1 mNET1/iso:1 enablesGO:0031267 small GTPase binding MGI_ref:5471195; PMID:23184663
PR:Q9Z206-2 mNET1/iso:2 acts_upstream_of_or_withinGO:1900026 positive regulation of substrate adhesion-dependent cell spreading MGI_ref:5471195; PMID:23184663
enablesGO:0031267 small GTPase binding MGI_ref:5471195; PMID:23184663
located_inGO:0005634 nucleus MGI_ref:5471195; PMID:23184663
GO:0005886 plasma membrane MGI_ref:5471195; PMID:23184663