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Protein Ontology report - bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
PR:000010724 - http://purl.obolibrary.org/obo/PR_000010724
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000010724   
  PRO namebifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 
  Synonyms
PRO-Short-label: EXACT:MTHFD2
Gene-based: RELATED:NMDMC
  Definition"A protein that is a translation product of the human MTHFD2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000010724

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

MTHFD2


"A protein that is a translation product of the human MTHFD2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P13995

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (human)

hMTHFD2


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P13995]


organism-sequence



PR:P13995-1

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 (human)

hMTHFD2/iso:1


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P13995-2

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform h2 (human)

hMTHFD2/iso:h2


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13995-2." [PRO:DNx, UniProtKB:P13995]


organism-modification



PR:000048470

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, transit peptide removed form (human)

hMTHFD2/TransPep-


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P13995, 36-350." [PRO:DNx, Reactome:R-HSA-6801347]


organism-modification



PR:000082894

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial deaminated 1 (human)

hMTHFD2/Deam:1


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (human) that has been deaminated on the residue at the position equivalent to Asn-87 of the amino acid sequence represented by UniProtKB:P13995-1. Example: UniProtKB:P13995-1, Asn-87, MOD:00684." [IEDB_epitope:1724572, PRO:DNx]


organism-gene



PR:P18155

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (mouse)

mMTHFD2


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that is encoded in the genome of mouse." [OMA:P18155, PRO:DNx]


organism-sequence



PR:P18155-1

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 (mouse)

mMTHFD2/iso:1


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q5ZKA5

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (chicken)

chick-MTHFD2


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:Q9P786

methylenetetrahydrofolate dehydrogenase [NAD(+)] (Schizosaccharomyces pombe 972h-)

Spom972h-MTHFD2


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]


sequence



PR:000038895

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1

MTHFD2/iso:1


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13995-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P13995-1

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 (human)

hMTHFD2/iso:1


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P18155-1

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 (mouse)

mMTHFD2/iso:1


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000020648

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, transit peptide removed form

MTHFD2/TransPep-


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial that has had the transit peptide removed." [PRO:DNx]


organism-modification



PR:000048470

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, transit peptide removed form (human)

hMTHFD2/TransPep-


"A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P13995, 36-350." [PRO:DNx, Reactome:R-HSA-6801347]