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Protein Ontology report - mediator of RNA polymerase II transcription subunit 4
PR:000010304 - http://purl.obolibrary.org/obo/PR_000010304
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010304   
  PRO namemediator of RNA polymerase II transcription subunit 4 
  Synonyms
PRO-Short-label: EXACT:MED4
Gene-based: RELATED:ARC36 | DRIP36 | HSPC126 | VDRIP
Other: EXACT:activator-recruited cofactor 36 kDa component | mediator complex subunit 4 | TRAP/SMCC/PC2 subunit p36 subunit | vitamin D3 receptor-interacting protein complex 36 kDa component
  Definition"A protein that is a translation product of the human MED4 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000010304

mediator of RNA polymerase II transcription subunit 4

MED4


"A protein that is a translation product of the human MED4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q23523

mediator of RNA polymerase II transcription subunit 4 (worm)

MED4 (worm)


"A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of worm." [PANTHER:PTHR13208:SF0, PRO:DNx]


organism-gene



PR:Q561Q8

mediator of RNA polymerase II transcription subunit 4 (rat)

rMED4


"A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of rat." [OMA:Q561Q8, PRO:DNx]


organism-gene



PR:Q561X3

mediator of RNA polymerase II transcription subunit 4 (zebrafish)

z-MED4


"A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of zebrafish." [OMA:Q561X3, PRO:DNx]


organism-gene



PR:Q9CQA5

mediator of RNA polymerase II transcription subunit 4 (mouse)

mMED4


"A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of mouse." [OMA:Q9CQA5, PRO:DNx]


organism-sequence



PR:Q9CQA5-1

mediator of RNA polymerase II transcription subunit 4 isoform 1 (mouse)

mMED4/iso:1


"A mediator of RNA polymerase II transcription subunit 4 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
organism-sequence



PR:Q9CQA5-2

mediator of RNA polymerase II transcription subunit 4 isoform m2 (mouse)

mMED4/iso:m2


"A mediator of RNA polymerase II transcription subunit 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CQA5-2." [PRO:DNx, UniProtKB:Q9CQA5]


organism-gene



PR:Q9NPJ6

mediator of RNA polymerase II transcription subunit 4 (human)

hMED4


"A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NPJ6]


organism-sequence



PR:Q9NPJ6-1

mediator of RNA polymerase II transcription subunit 4 isoform 1 (human)

hMED4/iso:1


"A mediator of RNA polymerase II transcription subunit 4 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q9NPJ6-2

mediator of RNA polymerase II transcription subunit 4 isoform h2 (human)

hMED4/iso:h2


"A mediator of RNA polymerase II transcription subunit 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NPJ6-2." [PRO:DNx, UniProtKB:Q9NPJ6]


organism-gene



PR:Q9VS38

mediator of RNA polymerase II transcription subunit 4 (fruit fly)

fly-MED4


"A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of fruit fly." [OMA:Q9VS38, PRO:DNx]


sequence



PR:000028890

mediator of RNA polymerase II transcription subunit 4 isoform 1

MED4/iso:1


"A mediator of RNA polymerase II transcription subunit 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CQA5-1 or a 1:1 ortholog thereof." [PMID:16141072, PRO:HJD]


organism-sequence



PR:Q9CQA5-1

mediator of RNA polymerase II transcription subunit 4 isoform 1 (mouse)

mMED4/iso:1


"A mediator of RNA polymerase II transcription subunit 4 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
organism-sequence



PR:Q9NPJ6-1

mediator of RNA polymerase II transcription subunit 4 isoform 1 (human)

hMED4/iso:1


"A mediator of RNA polymerase II transcription subunit 4 isoform 1 that is encoded in the genome of human." [PRO:HJD]


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MED4 forms found in complexes   

MED4 Component
Complexes
PR:Q9CQA5ZDASHZ1 mMED4/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9CQA5-1 mMED4/iso:1 located_inGO:0016592 mediator complex MGI_ref:4462751; PMID:20508642