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Protein Ontology report - mediator of RNA polymerase II transcription subunit 27
PR:000010299 - http://purl.obolibrary.org/obo/PR_000010299
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010299   
  PRO namemediator of RNA polymerase II transcription subunit 27 
  Synonyms
PRO-Short-label: EXACT:MED27
Gene-based: RELATED:CRSP34 | CRSP8
Other: EXACT:cofactor required for Sp1 transcriptional activation subunit 8 | CRSP complex subunit 8 | mediator complex subunit 27 | P37 TRAP/SMCC/PC2 subunit | transcriptional coactivator CRSP34
  Definition"A protein that is a translation product of the human MED27 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000010299

mediator of RNA polymerase II transcription subunit 27

MED27


"A protein that is a translation product of the human MED27 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q6P2C8

mediator of RNA polymerase II transcription subunit 27 (human)

hMED27


"A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6P2C8]


organism-sequence



PR:Q6P2C8-1

mediator of RNA polymerase II transcription subunit 27 isoform 1 (human)

hMED27/iso:1


"A mediator of RNA polymerase II transcription subunit 27 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q6P2C8-2

mediator of RNA polymerase II transcription subunit 27 isoform h2 (human)

hMED27/iso:h2


"A mediator of RNA polymerase II transcription subunit 27 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P2C8-2." [PRO:DNx, UniProtKB:Q6P2C8]


organism-sequence



PR:Q6P2C8-4

mediator of RNA polymerase II transcription subunit 27 isoform h3 (human)

hMED27/iso:h3


"A mediator of RNA polymerase II transcription subunit 27 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P2C8-4." [PRO:DNx, UniProtKB:Q6P2C8]


organism-modification



PR:000067041

mediator of RNA polymerase II transcription subunit 27 methylated 1 (human)

hMED27/Me:1


"A mediator of RNA polymerase II transcription subunit 27 (human) that has been methylated on the residue at the position equivalent to Cys-281 of the amino acid sequence represented by UniProtKB:Q6P2C8-1. Example: UniProtKB:Q6P2C8-1, Cys-281, MOD:00660." [IEDB_epitope:1024791, PRO:DNx]


organism-modification



PR:000074837

mediator of RNA polymerase II transcription subunit 27 cysteinylated 1 (human)

hMED27/Cyst:1


"A mediator of RNA polymerase II transcription subunit 27 (human) that has been cysteinylated on the residue at the position equivalent to Cys-281 of the amino acid sequence represented by UniProtKB:Q6P2C8-1. Example: UniProtKB:Q6P2C8-1, Cys-281, MOD:00765." [IEDB_epitope:1024790, PRO:DNx]


organism-modification



PR:000077385

mediator of RNA polymerase II transcription subunit 27 deaminated 1 (human)

hMED27/Deam:1


"A mediator of RNA polymerase II transcription subunit 27 (human) that has been deaminated on the residue at the position equivalent to Asn-218 of the amino acid sequence represented by UniProtKB:Q6P2C8-1. Example: UniProtKB:Q6P2C8-1, Asn-218, MOD:00684." [IEDB_epitope:1575672, PRO:DNx]


organism-modification



PR:000080616

mediator of RNA polymerase II transcription subunit 27 deaminated 2 (human)

hMED27/Deam:2


"A mediator of RNA polymerase II transcription subunit 27 (human) that has been deaminated on the residue at the position equivalent to Asn-220 of the amino acid sequence represented by UniProtKB:Q6P2C8-1. Example: UniProtKB:Q6P2C8-1, Asn-220, MOD:00684." [IEDB_epitope:1575673, PRO:DNx]


organism-gene



PR:Q6PFL0

mediator of RNA polymerase II transcription subunit 27 (zebrafish)

z-MED27


"A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of zebrafish." [OMA:Q6PFL0, PRO:DNx]


organism-gene



PR:Q9DB40

mediator of RNA polymerase II transcription subunit 27 (mouse)

mMED27


"A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of mouse." [OMA:Q9DB40, PRO:DNx]


organism-sequence



PR:Q9DB40-1

mediator of RNA polymerase II transcription subunit 27 isoform 1 (mouse)

mMED27/iso:1


"A mediator of RNA polymerase II transcription subunit 27 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
organism-sequence



PR:Q9DB40-2

mediator of RNA polymerase II transcription subunit 27 isoform m2 (mouse)

mMED27/iso:m2


"A mediator of RNA polymerase II transcription subunit 27 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9DB40-2." [PRO:DNx, UniProtKB:Q9DB40]


organism-gene



PR:Q9VNG0

mediator of RNA polymerase II transcription subunit 27 (fruit fly)

fly-MED27


"A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of fruit fly." [OMA:Q9VNG0, PRO:DNx]


sequence



PR:000028910

mediator of RNA polymerase II transcription subunit 27 isoform 1

MED27/iso:1


"A mediator of RNA polymerase II transcription subunit 27 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9DB40-1 or a 1:1 ortholog thereof." [PMID:16141072, PRO:HJD]


organism-sequence



PR:Q6P2C8-1

mediator of RNA polymerase II transcription subunit 27 isoform 1 (human)

hMED27/iso:1


"A mediator of RNA polymerase II transcription subunit 27 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q9DB40-1

mediator of RNA polymerase II transcription subunit 27 isoform 1 (mouse)

mMED27/iso:1


"A mediator of RNA polymerase II transcription subunit 27 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
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MED27 forms found in complexes   

MED27 Component
Complexes
PR:Q9DB40ZDASHZ1 mMED27/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9DB40-1 mMED27/iso:1 located_inGO:0016592 mediator complex MGI_ref:4462751; PMID:20508642