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Protein Ontology report - mediator of RNA polymerase II transcription subunit 21
PR:000010293 - http://purl.obolibrary.org/obo/PR_000010293
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010293   
  PRO namemediator of RNA polymerase II transcription subunit 21 
  Synonyms
PRO-Short-label: EXACT:MED21
Gene-based: RELATED:SRB7 | SURB7
Other: EXACT:mediator complex subunit 21 | RNA polymerase II holoenzyme component SRB7 | RNAPII complex component SRB7
  Definition"A protein that is a translation product of the human MED21 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000010293

mediator of RNA polymerase II transcription subunit 21

MED21


"A protein that is a translation product of the human MED21 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:C0LU16

mediator of RNA polymerase II transcription subunit 21 (Arabidopsis thaliana)

At-MED21


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of Arabidopsis thaliana." [PANTHER:PTHR13381:SF0, PRO:DNx]


organism-gene



PR:D4AA11

protein Med21 (rat)

rMED21


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of rat." [OMA:D4AA11, PRO:DNx]


organism-gene



PR:Q13503

mediator of RNA polymerase II transcription subunit 21 (human)

hMED21


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13503]


organism-sequence



PR:Q13503-1

mediator of RNA polymerase II transcription subunit 21 isoform 1 (human)

hMED21/iso:1


"A mediator of RNA polymerase II transcription subunit 21 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-modification



PR:000084726

mediator of RNA polymerase II transcription subunit 21 phosphorylated 1 (human)

hMED21/Phos:1


"A mediator of RNA polymerase II transcription subunit 21 (human) that has been phosphorylated on the residue at the position equivalent to Ser-78 of the amino acid sequence represented by UniProtKB:Q13503. UniProtKB:Q13503, Ser-78, MOD:00046." [IEDB_epitope:1362727, PRO:DNx]


organism-gene



PR:Q6BER6

mediator of RNA polymerase II transcription subunit 21 (worm)

MED21 (worm)


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of worm." [OMA:Q6BER6, PRO:DNx]


organism-gene



PR:Q7ZTI5

mediator of RNA polymerase II transcription subunit 21 (zebrafish)

z-MED21


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of zebrafish." [OMA:Q7ZTI5, PRO:DNx]


organism-gene



PR:Q9CQ39

mediator of RNA polymerase II transcription subunit 21 (mouse)

mMED21


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of mouse." [OMA:Q9CQ39, PRO:DNx]


organism-sequence



PR:Q9CQ39-1

mediator of RNA polymerase II transcription subunit 21 isoform 1 (mouse)

mMED21/iso:1


"A mediator of RNA polymerase II transcription subunit 21 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
organism-gene



PR:Q9W5P1

mediator of RNA polymerase II transcription subunit 21 (fruit fly)

fly-MED21


"A mediator of RNA polymerase II transcription subunit 21 that is encoded in the genome of fruit fly." [OMA:Q9W5P1, PRO:DNx]


sequence



PR:000028898

mediator of RNA polymerase II transcription subunit 21 isoform 1

MED21/iso:1


"A mediator of RNA polymerase II transcription subunit 21 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CQ39-1 or a 1:1 ortholog thereof." [PMID:16141072, PRO:HJD]


organism-sequence



PR:Q13503-1

mediator of RNA polymerase II transcription subunit 21 isoform 1 (human)

hMED21/iso:1


"A mediator of RNA polymerase II transcription subunit 21 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q9CQ39-1

mediator of RNA polymerase II transcription subunit 21 isoform 1 (mouse)

mMED21/iso:1


"A mediator of RNA polymerase II transcription subunit 21 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]

Yes

Yes
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MED21 forms found in complexes   

MED21 Component
Complexes
PR:Q9CQ39ZDASHZ1 mMED21/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9CQ39-1 mMED21/iso:1 located_inGO:0016592 mediator complex MGI_ref:4462751; PMID:20508642