back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - mediator of RNA polymerase II transcription subunit 16
PR:000010288 - http://purl.obolibrary.org/obo/PR_000010288
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010288   
  PRO namemediator of RNA polymerase II transcription subunit 16 
  Synonyms
PRO-Short-label: EXACT:MED16
Gene-based: RELATED:DRIP92 | THRAP5
Other: EXACT:mediator complex subunit 16 | thyroid hormone receptor-associated protein 5 | thyroid hormone receptor-associated protein complex 95 kDa component | Trap95 | vitamin D3 receptor-interacting protein complex 92 kDa component
  Definition"A protein that is a translation product of the human MED16 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000010288
mediator of RNA polymerase II transcription subunit 16
MED16
"A protein that is a translation product of the human MED16 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q6PGF3
mediator of RNA polymerase II transcription subunit 16 (mouse)
mMED16
"A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of mouse." [OMA:Q6PGF3, PRO:DNx]

organism-sequence


PR:Q6PGF3-1
mediator of RNA polymerase II transcription subunit 16 isoform 1 (mouse)
mMED16/iso:1
"A mediator of RNA polymerase II transcription subunit 16 isoform 1 that is encoded in the genome of mouse." [PMID:15489334, PRO:HJD]
Yes
Yes
organism-gene


PR:Q9W278
mediator of RNA polymerase II transcription subunit 16 (fruit fly)
fly-MED16
"A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of fruit fly." [OMA:Q9W278, PRO:DNx]

organism-gene


PR:Q9Y2X0
mediator of RNA polymerase II transcription subunit 16 (human)
hMED16
"A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y2X0]

organism-sequence


PR:Q9Y2X0-1
mediator of RNA polymerase II transcription subunit 16 isoform h1 (human)
hMED16/iso:h1
"A mediator of RNA polymerase II transcription subunit 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2X0-1." [PRO:DNx, UniProtKB:Q9Y2X0]

organism-sequence


PR:Q9Y2X0-2
mediator of RNA polymerase II transcription subunit 16 isoform h2 (human)
hMED16/iso:h2
"A mediator of RNA polymerase II transcription subunit 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2X0-2." [PRO:DNx, UniProtKB:Q9Y2X0]

organism-sequence


PR:Q9Y2X0-3
mediator of RNA polymerase II transcription subunit 16 isoform h3 (human)
hMED16/iso:h3
"A mediator of RNA polymerase II transcription subunit 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2X0-3." [PRO:DNx, UniProtKB:Q9Y2X0]

organism-sequence


PR:Q9Y2X0-4
mediator of RNA polymerase II transcription subunit 16 isoform h4 (human)
hMED16/iso:h4
"A mediator of RNA polymerase II transcription subunit 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2X0-4." [PRO:DNx, UniProtKB:Q9Y2X0]

organism-sequence


PR:Q9Y2X0-5
mediator of RNA polymerase II transcription subunit 16 isoform h5 (human)
hMED16/iso:h5
"A mediator of RNA polymerase II transcription subunit 16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2X0-5." [PRO:DNx, UniProtKB:Q9Y2X0]

organism-modification


PR:000067434
mediator of RNA polymerase II transcription subunit 16 methylated 1 (human)
hMED16/Me:1
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been methylated on the residue at the position equivalent to Cys-308 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-308, MOD:00660." [IEDB_epitope:1039628, PRO:DNx]

organism-modification


PR:000068519
mediator of RNA polymerase II transcription subunit 16 methylated 2 (human)
hMED16/Me:2
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been methylated on the residue at the position equivalent to Cys-539 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-539, MOD:00660." [IEDB_epitope:1025217, PRO:DNx]

organism-modification


PR:000068963
mediator of RNA polymerase II transcription subunit 16 methylated 3 (human)
hMED16/Me:3
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been methylated on the residue at the position equivalent to Cys-86 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-86, MOD:00660." [IEDB_epitope:1017947, PRO:DNx]

organism-modification


PR:000071380
mediator of RNA polymerase II transcription subunit 16 cysteinylated 1 (human)
hMED16/Cyst:1
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been cysteinylated on the residue at the position equivalent to Cys-86 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-86, MOD:00765." [IEDB_epitope:1017946, PRO:DNx]

organism-modification


PR:000071718
mediator of RNA polymerase II transcription subunit 16 cysteinylated 2 (human)
hMED16/Cyst:2
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been cysteinylated on the residue at the position equivalent to Cys-308 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-308, MOD:00765." [IEDB_epitope:929837, PRO:DNx]

organism-modification


PR:000075726
mediator of RNA polymerase II transcription subunit 16 glutathionylated 1 (human)
hMED16/SGlt:1
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been glutathionylated on the residue at the position equivalent to Cys-308 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-308, MOD:00234." [IEDB_epitope:422646, PRO:DNx]

organism-modification


PR:000075757
mediator of RNA polymerase II transcription subunit 16 methylated 4 (human)
hMED16/Me:4
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been methylated on the residue at the position equivalent to Cys-584 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-584, MOD:00660." [IEDB_epitope:1043547, PRO:DNx]

organism-modification


PR:000078889
mediator of RNA polymerase II transcription subunit 16 methylated 5 (human)
hMED16/Me:5
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been methylated on the residue at the position equivalent to Cys-545 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-545, MOD:00660." [IEDB_epitope:1046459, PRO:DNx]

organism-modification


PR:000081946
mediator of RNA polymerase II transcription subunit 16 methylated 6 (human)
hMED16/Me:6
"A mediator of RNA polymerase II transcription subunit 16 (human) that has been methylated on the residue at the position equivalent to Cys-672 of the amino acid sequence represented by UniProtKB:Q9Y2X0-1. Example: UniProtKB:Q9Y2X0-1, Cys-672, MOD:00660." [IEDB_epitope:1015753, PRO:DNx]

sequence


PR:000028914
mediator of RNA polymerase II transcription subunit 16 isoform 1
MED16/iso:1
"A mediator of RNA polymerase II transcription subunit 16 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PGF3-1 or a 1:1 ortholog thereof." [PMID:15489334, PRO:HJD]

organism-sequence


PR:Q6PGF3-1
mediator of RNA polymerase II transcription subunit 16 isoform 1 (mouse)
mMED16/iso:1
"A mediator of RNA polymerase II transcription subunit 16 isoform 1 that is encoded in the genome of mouse." [PMID:15489334, PRO:HJD]
Yes
Yes
Back to top
MED16 forms found in complexes   

MED16 Component
 Complexes
PR:Q6PGF3ZDASHZ1 mMED16/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q6PGF3-1 mMED16/iso:1 located_inGO:0016592 mediator complex MGI_ref:4462751; PMID:20508642