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Protein Ontology report - leucine--tRNA ligase, cytoplasmic
PR:000009674 - http://purl.obolibrary.org/obo/PR_000009674
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000009674   
  PRO nameleucine--tRNA ligase, cytoplasmic 
  Synonyms
PRO-Short-label: EXACT:LARS1
Gene-based: RELATED:KIAA1352 | LARS
Other: EXACT:leucyl-tRNA synthetase, cytoplasmic
  Definition"A protein that is a translation product of the human LARS1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009674

leucine--tRNA ligase, cytoplasmic

LARS1


"A protein that is a translation product of the human LARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:F4I116

leucine--tRNA ligase, cytoplasmic (Arabidopsis thaliana)

At-LARS


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of Arabidopsis thaliana." [OMA:F4I116, PRO:DNx]


organism-gene



PR:P26637

leucine--tRNA ligase, cytoplasmic (yeast)

yLARS


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of yeast." [OMA:P26637, PRO:DNx]


organism-gene



PR:Q09996

leucine--tRNA ligase (worm)

LARS (worm)


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of worm." [OMA:Q09996, PRO:DNx]


organism-gene



PR:Q10490

putative leucine--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-)

Spom972h-LARS


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q10490, PRO:DNx]


organism-gene



PR:Q54N83

leucine--tRNA ligase, cytoplasmic (Dictyostelium discoideum)

Dicty-LARS


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54N83, PRO:DNx]


organism-gene



PR:Q8BMJ2

leucine--tRNA ligase, cytoplasmic (mouse)

mLARS


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q8BMJ2, PRO:DNx]


organism-gene



PR:Q9P2J5

leucine--tRNA ligase, cytoplasmic (human)

hLARS1


"A leucine--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:Q9P2J5-1

leucine--tRNA ligase, cytoplasmic isoform h1 (human)

hLARS1/iso:h1


"A leucine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2J5-1." [PRO:DNx, UniProtKB:Q9P2J5]


organism-sequence



PR:Q9P2J5-2

leucine--tRNA ligase, cytoplasmic isoform h2 (human)

hLARS1/iso:h2


"A leucine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2J5-2." [PRO:DNx, UniProtKB:Q9P2J5]


organism-sequence



PR:Q9P2J5-3

leucine--tRNA ligase, cytoplasmic isoform h3 (human)

hLARS1/iso:h3


"A leucine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2J5-3." [PRO:DNx, UniProtKB:Q9P2J5]


organism-modification



PR:000066559

leucine--tRNA ligase, cytoplasmic cysteinylated 1 (human)

hLARS1/Cyst:1


"A leucine--tRNA ligase, cytoplasmic (human) that has been cysteinylated on the residue at the position equivalent to Cys-248 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-248, MOD:00765." [IEDB_epitope:1589694, PRO:DNx]


organism-modification



PR:000068151

leucine--tRNA ligase, cytoplasmic methylated 1 (human)

hLARS1/Me:1


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-522 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-522, MOD:00660." [IEDB_epitope:1051662, PRO:DNx]


organism-modification



PR:000075806

leucine--tRNA ligase, cytoplasmic methylated 2 (human)

hLARS1/Me:2


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-70 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-70, MOD:00660." [IEDB_epitope:1049483, PRO:DNx]


organism-modification



PR:000078083

leucine--tRNA ligase, cytoplasmic phosphorylated 1 (human)

hLARS1/Phos:1


"A leucine--tRNA ligase, cytoplasmic (human) that has been phosphorylated on the residue at the position equivalent to Thr-726 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Thr-726, MOD:00047." [IEDB_epitope:1354800, PRO:DNx]


organism-modification



PR:000078347

leucine--tRNA ligase, cytoplasmic methylated 3 (human)

hLARS1/Me:3


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-1093 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-1093, MOD:00660." [IEDB_epitope:1005793, PRO:DNx]


organism-modification



PR:000078885

leucine--tRNA ligase, cytoplasmic methylated 4 (human)

hLARS1/Me:4


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-863 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-863, MOD:00660." [IEDB_epitope:1029781, PRO:DNx]


organism-modification



PR:000081915

leucine--tRNA ligase, cytoplasmic methylated 5 (human)

hLARS1/Me:5


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-867 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-867, MOD:00660." [IEDB_epitope:1018192, PRO:DNx]


organism-modification



PR:000083358

leucine--tRNA ligase, cytoplasmic methylated 6 (human)

hLARS1/Me:6


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-446 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-446, MOD:00660." [IEDB_epitope:1047761, PRO:DNx]


organism-modification



PR:000085402

leucine--tRNA ligase, cytoplasmic methylated 7 (human)

hLARS1/Me:7


"A leucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-100 of the amino acid sequence represented by UniProtKB:Q9P2J5-1. Example: UniProtKB:Q9P2J5-1, Cys-100, MOD:00660." [IEDB_epitope:1033917, PRO:DNx]


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LARS1 forms found in complexes   

LARS1 Component
Complexes
PR:Q9P2J5 hLARS1 PR:000027407 aminoacyl-tRNA synthetase multienzyme complex (human)