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Protein Ontology report - GTPase KRas
PR:000009442 - http://purl.obolibrary.org/obo/PR_000009442
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000009442   
  PRO nameGTPase KRas 
  Synonyms
PRO-Short-label: EXACT:KRAS
Gene-based: RELATED:KRAS2 | RASK2
Other: EXACT:c-K-ras | c-Ki-ras | K-Ras 2 | Ki-Ras
  Definition"A protein that is a translation product of the human KRAS gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 8                                        
         Modification2                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2824
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009442

GTPase KRas

KRAS


"A protein that is a translation product of the human KRAS gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P01116

GTPase KRas (human)

hKRAS


"A GTPase KRas that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01116]


organism-sequence



PR:P01116-1

GTPase KRas isoform 2A (human)

hKRAS/iso:2A


"A GTPase KRas isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000061735

GTPase KRas isoform 2A farnesylated 1 (human)

hKRAS/iso:2A/Farn:1


"A GTPase KRas isoform 2A (human) that has been farnesylated on the residue at the position equivalent to Cys-186 of the amino acid sequence represented by UniProtKB:P01116-1. UniProtKB:P01116-1, Cys-186, MOD:00111." [PRO:DNx, Reactome:R-HSA-9649695]


organism-sequence



PR:P01116-2

GTPase KRas isoform 2B (human)

hKRAS/iso:2B


"A GTPase KRas isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000060918

GTPase KRas isoform 2B farnesylated 1 (human)

hKRAS/iso:2B/Farn:1


"A GTPase KRas isoform 2B (human) that has been farnesylated on the residue at the position equivalent to Cys-185 of the amino acid sequence represented by UniProtKB:P01116-2. UniProtKB:P01116-2, Cys-185, MOD:00111." [PRO:DNx, Reactome:R-HSA-9649693]


organism-modification



PR:000063874

GTPase KRas farnesylated 1 (human)

hKRAS/Farn:1


"A GTPase KRas (human) that has been farnesylated on the residue at the position equivalent to Cys-186 of the amino acid sequence represented by UniProtKB:P01116-1. Example: UniProtKB:P01116-1, Cys-186, MOD:00111." [PRO:DNx, Reactome:R-HSA-9647925]


organism-modification



PR:000083857

GTPase KRas deaminated 1 (human)

hKRAS/Deam:1


"A GTPase KRas (human) that has been deaminated on the residue at the position equivalent to Gln-43 of the amino acid sequence represented by UniProtKB:P01116-1. Example: UniProtKB:P01116-1, Gln-43, MOD:00685." [IEDB_epitope:1566224, PRO:DNx]


organism-gene



PR:P08644

GTPase KRas (rat)

rKRAS


"A GTPase KRas that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P08644-1

GTPase KRas isoform 2A (rat)

rKRAS/iso:2A


"A GTPase KRas isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P08644-2

GTPase KRas isoform 2B (rat)

rKRAS/iso:2B


"A GTPase KRas isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P32883

GTPase KRas (mouse)

mKRAS


"A GTPase KRas that is encoded in the genome of mouse." [OMA:P32883, PRO:DNx]


organism-sequence



PR:000049752

GTPase KRas sequence variant (mouse)

mKRAS/var+


"A GTPase KRas (mouse) that has at least one amino acid residue that differs from the corresponding residue found in another GTPase KRas (mouse) when such a difference arises as the result of genetic differences, i.e., different alleles of GTPase KRas (mouse). Operationally, this means the sequence representation of the GTPase KRas (mouse) has at least one amino acid residue that differs from the corresponding residue found in the sequence represented by UniProtKB:P32883." [PRO:CNA]


organism-sequence



PR:000049753

GTPase KRas sequence variant G12D (mouse)

mKRAS/var:G12D


"A GTPase KRas sequence variant (mouse) that has an Asp residue at the position equivalent to Gly-12 of the amino acid sequence represented by UniProtKB:P32883-1. Example: UniProtKB:P32883-1, Gly-12, CHEBI:29958." [MGI:96680, PMID:11323676, PRO:HJD]


organism-sequence



PR:P32883-1

GTPase KRas isoform 2A (mouse)

mKRAS/iso:2A


"A GTPase KRas isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P32883-2

GTPase KRas isoform 2B (mouse)

mKRAS/iso:2B


"A GTPase KRas isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q59XU5

Ras-like protein 1 (Candida albicans SC5314)

Calb-KRAS


"A GTPase KRas that is encoded in the genome of Candida albicans SC5314." [OMA:Q59XU5, PRO:DNx]


sequence



PR:000038615

GTPase KRas isoform 1

KRAS/iso:1


"A GTPase KRas that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01116-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P01116-1

GTPase KRas isoform 2A (human)

hKRAS/iso:2A


"A GTPase KRas isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000061735

GTPase KRas isoform 2A farnesylated 1 (human)

hKRAS/iso:2A/Farn:1


"A GTPase KRas isoform 2A (human) that has been farnesylated on the residue at the position equivalent to Cys-186 of the amino acid sequence represented by UniProtKB:P01116-1. UniProtKB:P01116-1, Cys-186, MOD:00111." [PRO:DNx, Reactome:R-HSA-9649695]


organism-sequence



PR:P08644-1

GTPase KRas isoform 2A (rat)

rKRAS/iso:2A


"A GTPase KRas isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P32883-1

GTPase KRas isoform 2A (mouse)

mKRAS/iso:2A


"A GTPase KRas isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038616

GTPase KRas isoform 2

KRAS/iso:2


"A GTPase KRas that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01116-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P01116-2

GTPase KRas isoform 2B (human)

hKRAS/iso:2B


"A GTPase KRas isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000060918

GTPase KRas isoform 2B farnesylated 1 (human)

hKRAS/iso:2B/Farn:1


"A GTPase KRas isoform 2B (human) that has been farnesylated on the residue at the position equivalent to Cys-185 of the amino acid sequence represented by UniProtKB:P01116-2. UniProtKB:P01116-2, Cys-185, MOD:00111." [PRO:DNx, Reactome:R-HSA-9649693]


organism-sequence



PR:P08644-2

GTPase KRas isoform 2B (rat)

rKRAS/iso:2B


"A GTPase KRas isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P32883-2

GTPase KRas isoform 2B (mouse)

mKRAS/iso:2B


"A GTPase KRas isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000020401

GTPase KRas, initiator methionine removed form

KRAS/InitMet-


"A GTPase KRas that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000020402

GTPase KRas proteolytic cleavage product

KRAS/ClvPrd


"A GTPase KRas that has been processed by proteolytic cleavage." [PRO:DNx]