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Protein Ontology report - integrin alpha-6
PR:000009131 - http://purl.obolibrary.org/obo/PR_000009131
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000009131   
  PRO nameintegrin alpha-6 
  Synonyms
PRO-Short-label: EXACT:ITGA6
Other: EXACT:CD49 antigen-like family member F | CD49f | VLA-6
  Definition"An integrin alpha lacking A domain that is a translation product of the human ITGA6 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000025797 integrin alpha lacking A domain
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 10                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2445
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009131

integrin alpha-6

ITGA6


"An integrin alpha lacking A domain that is a translation product of the human ITGA6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P23229

integrin alpha-6 (human)

hITGA6


"An integrin alpha-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P23229]


organism-sequence



PR:P23229-1

integrin alpha-6 isoform hAlpha-6X1X2B (human)

hITGA6/iso:hAlpha-6X1X2B


"An integrin alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-1." [PRO:DNx, UniProtKB:P23229]


organism-sequence



PR:P23229-2

integrin alpha-6 isoform Alpha-6X1A (human)

hITGA6/iso:Alpha-6X1A


"An integrin alpha-6 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P23229-3

integrin alpha-6 isoform Alpha-6X1B (human)

hITGA6/iso:Alpha-6X1B


"An integrin alpha-6 isoform Alpha-6X1B that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P23229-4

integrin alpha-6 isoform hAlpha-6X2A (human)

hITGA6/iso:hAlpha-6X2A


"An integrin alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-4." [PRO:DNx, UniProtKB:P23229]


organism-sequence



PR:P23229-5

integrin alpha-6 isoform hAlpha-6X2B (human)

hITGA6/iso:hAlpha-6X2B


"An integrin alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-5." [PRO:DNx, UniProtKB:P23229]


organism-sequence



PR:P23229-6

integrin alpha-6 isoform hAlpha-6X1X2A (human)

hITGA6/iso:hAlpha-6X1X2A


"An integrin alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-6." [PRO:DNx, UniProtKB:P23229]


organism-sequence



PR:P23229-7

integrin alpha-6 isoform h7 (human)

hITGA6/iso:h7


"An integrin alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-7." [PRO:DNx, UniProtKB:P23229]


organism-sequence



PR:P23229-9

integrin alpha-6 isoform h9 (human)

hITGA6/iso:h9


"An integrin alpha-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-9." [PRO:DNx, UniProtKB:P23229]


organism-modification



PR:000048062

integrin alpha-6, signal peptide removed form (human)

hITGA6/SigPep-


"An integrin alpha-6 (human) that has had the signal peptide removed. UniProtKB:P23229, 24-1130." [PRO:DNx, Reactome:R-HSA-204439]


organism-modification



PR:000056209

integrin alpha-6 N-glycosylated 1 (human)

hITGA6/NGlyco:1


"An integrin alpha-6 (human) that has been N-glycosylated at the residue equivalent to Asn-997 of the amino acid sequence represented by UniProtKB:P23229-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P23229-1, Asn-997, MOD:00160~GNO:G25079LO." [GlyGen:P23229-1, PMID:29741879, PRO:DNx]


organism-gene



PR:P26007

integrin alpha-6 (chicken)

chick-ITGA6


"An integrin alpha-6 that is encoded in the genome of chicken." [OMA:P26007, PRO:DNx]


organism-gene



PR:Q61739

integrin alpha-6 (mouse)

mITGA6


"An integrin alpha-6 that is encoded in the genome of mouse." [OMA:Q61739, PRO:DNx]


organism-sequence



PR:Q61739-1

integrin alpha-6 isoform Alpha-6X1B (mouse)

mITGA6/iso:Alpha-6X1B


"An integrin alpha-6 isoform Alpha-6X1B that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q61739-2

integrin alpha-6 isoform Alpha-6X1A (mouse)

mITGA6/iso:Alpha-6X1A


"An integrin alpha-6 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

Yes

sequence



PR:000039087

integrin alpha-6 isoform 2

ITGA6/iso:2


"An integrin alpha-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P23229-2

integrin alpha-6 isoform Alpha-6X1A (human)

hITGA6/iso:Alpha-6X1A


"An integrin alpha-6 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q61739-2

integrin alpha-6 isoform Alpha-6X1A (mouse)

mITGA6/iso:Alpha-6X1A


"An integrin alpha-6 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

Yes

sequence



PR:000039088

integrin alpha-6 isoform Alpha-6X1B

ITGA6/iso:Alpha-6X1B


"An integrin alpha-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23229-3 or a 1:1 ortholog thereof." [PRO:DAN]


organism-sequence



PR:P23229-3

integrin alpha-6 isoform Alpha-6X1B (human)

hITGA6/iso:Alpha-6X1B


"An integrin alpha-6 isoform Alpha-6X1B that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q61739-1

integrin alpha-6 isoform Alpha-6X1B (mouse)

mITGA6/iso:Alpha-6X1B


"An integrin alpha-6 isoform Alpha-6X1B that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000020338

integrin alpha-6, signal peptide removed form

ITGA6/SigPep-


"An integrin alpha-6 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000048062

integrin alpha-6, signal peptide removed form (human)

hITGA6/SigPep-


"An integrin alpha-6 (human) that has had the signal peptide removed. UniProtKB:P23229, 24-1130." [PRO:DNx, Reactome:R-HSA-204439]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q61739-2 mITGA6/iso:Alpha-6X1A acts_upstream_of_or_withinGO:0033627 cell adhesion mediated by integrin MGI_ref:75849; PMID:1833411
enablesGO:0005178 integrin binding with PR:P09055 CD29 (mouse) MGI_ref:75849; PMID:1833411
located_inGO:0009986 cell surface MGI_ref:75849; PMID:1833411