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Protein Ontology report - integrin alpha-IIb
PR:000009127 - http://purl.obolibrary.org/obo/PR_000009127
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000009127   
  PRO nameintegrin alpha-IIb 
  Synonyms
PRO-Short-label: EXACT:ITGA2B
Gene-based: RELATED:GP2B | ITGAB
Other: EXACT:CD41 | GPalpha IIb | GPIIb | platelet membrane glycoprotein IIb
  Definition"An integrin alpha lacking A domain that is a translation product of the human ITGA2B gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000025797 integrin alpha lacking A domain
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification2                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2441
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000009127

integrin alpha-IIb

ITGA2B


"An integrin alpha lacking A domain that is a translation product of the human ITGA2B gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P08514

integrin alpha-IIb (human)

hITGA2B


"An integrin alpha-IIb that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08514]


organism-sequence



PR:P08514-1

integrin alpha-IIb isoform h1 (human)

hITGA2B/iso:h1


"An integrin alpha-IIb (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08514-1." [PRO:DNx, UniProtKB:P08514]


organism-sequence



PR:P08514-2

integrin alpha-IIb isoform h2 (human)

hITGA2B/iso:h2


"An integrin alpha-IIb (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08514-2." [PRO:DNx, UniProtKB:P08514]


organism-sequence



PR:P08514-3

integrin alpha-IIb isoform h3 (human)

hITGA2B/iso:h3


"An integrin alpha-IIb (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08514-3." [PRO:DNx, UniProtKB:P08514]


organism-modification



PR:000028409

integrin alpha-IIb, signal peptide removed form (human)

hITGA2B/SigPep-


"An integrin alpha-IIb, signal peptide removed form in human. Example: UniProtKB:P08514-1, 32-1039." [PRO:DNx]


Yes
organism-modification



PR:000054447

integrin alpha-IIb O-glycosylated 1 (human)

hITGA2B/OGlyco:1


"An integrin alpha-IIb (human) that has been O-glycosylated at the residue equivalent to Ser-876 of the amino acid sequence represented by UniProtKB:P08514-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:P08514-1, Ser-876, MOD:00002~GNO:G53434XO." [GlyGen:P08514-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000054448

integrin alpha-IIb O-glycosylated 2 (human)

hITGA2B/OGlyco:2


"An integrin alpha-IIb (human) that has been O-glycosylated at the residue equivalent to Ser-876 of the amino acid sequence represented by UniProtKB:P08514-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P08514-1, Ser-876, MOD:00002~GNO:G58001LT." [GlyGen:P08514-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000054449

integrin alpha-IIb O-glycosylated 3 (human)

hITGA2B/OGlyco:3


"An integrin alpha-IIb (human) that has been O-glycosylated at the residue equivalent to Ser-878 of the amino acid sequence represented by UniProtKB:P08514-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P08514-1, Ser-878, MOD:00002~GNO:G29068FM." [GlyGen:P08514-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000054450

integrin alpha-IIb O-glycosylated 4 (human)

hITGA2B/OGlyco:4


"An integrin alpha-IIb (human) that has been O-glycosylated at the residue equivalent to Ser-878 of the amino acid sequence represented by UniProtKB:P08514-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08514-1, Ser-878, MOD:00002~GNO:G43417UB." [GlyGen:P08514-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000067978

integrin alpha-IIb deaminated 1 (human)

hITGA2B/Deam:1


"An integrin alpha-IIb (human) that has been deaminated on the residue at the position equivalent to Asn-711 of the amino acid sequence represented by UniProtKB:P08514-1. Example: UniProtKB:P08514-1, Asn-711, MOD:00684." [IEDB_epitope:927580, PRO:DNx]


organism-modification



PR:000083741

integrin alpha-IIb phosphorylated 1 (human)

hITGA2B/Phos:1


"An integrin alpha-IIb (human) that has been phosphorylated on the residue at the position equivalent to Thr-107 of the amino acid sequence represented by UniProtKB:P08514-1. Example: UniProtKB:P08514-1, Thr-107, MOD:00047." [IEDB_epitope:2146038, PRO:DNx]


organism-gene



PR:P12080

integrin alpha-PS2 (fruit fly)

fly-ITGA2B


"An integrin alpha-IIb that is encoded in the genome of fruit fly." [OMA:P12080, PRO:DNx]


organism-sequence



PR:P12080-1

integrin alpha-PS2 isoform PS2C (fruit fly)

fly-ITGA2B/iso:PS2C


"An integrin alpha-PS2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12080-1." [PRO:DNx, UniProtKB:P12080]


organism-sequence



PR:P12080-2

integrin alpha-PS2 isoform PS2M8 (fruit fly)

fly-ITGA2B/iso:PS2M8


"An integrin alpha-PS2 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12080-2." [PRO:DNx, UniProtKB:P12080]


organism-gene



PR:Q9QUM0

integrin alpha-IIb (mouse)

mITGA2B


"An integrin alpha-IIb that is encoded in the genome of mouse." [OMA:Q9QUM0, PRO:DNx]


modification



PR:000020328

integrin alpha-IIb, signal peptide removed form

ITGA2B/SigPep-


"An integrin alpha-IIb that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000028409

integrin alpha-IIb, signal peptide removed form (human)

hITGA2B/SigPep-


"An integrin alpha-IIb, signal peptide removed form in human. Example: UniProtKB:P08514-1, 32-1039." [PRO:DNx]


Yes
modification



PR:000020329

integrin alpha-IIb proteolytic cleavage product

ITGA2B/ClvPrd


"An integrin alpha-IIb that has been processed by proteolytic cleavage." [PRO:DNx]


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ITGA2B forms found in complexes   

ITGA2B Component
Complexes
PR:000028409 hITGA2B/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)