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Protein Ontology report - inner centromere protein
PR:000009029 - http://purl.obolibrary.org/obo/PR_000009029
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000009029   
  PRO nameinner centromere protein 
  Synonyms
PRO-Short-label: EXACT:INCENP
  Definition"A protein that is a translation product of the human INCENP gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification2                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000009029 inner centromere protein
INCENP

organism-gene


PR:P53352 inner centromere protein (chicken)
chick-INCENP

organism-sequence


PR:P53352-1 inner centromere protein isoform INCENP II (chicken)
chick-INCENP/iso:INCENP II

organism-sequence


PR:P53352-2 inner centromere protein isoform INCENP I (chicken)
chick-INCENP/iso:INCENP I

organism-gene


PR:Q9NQS7 inner centromere protein (human)
hINCENP
Yes
organism-sequence


PR:Q9NQS7-1 inner centromere protein isoform h1 (human)
hINCENP/iso:h1

organism-sequence


PR:Q9NQS7-2 inner centromere protein isoform h2 (human)
hINCENP/iso:h2

organism-modification


PR:000035527 inner centromere protein phosphorylated 1 (human)
hINCENP/Phos:1
Yes
organism-modification


PR:000035529 inner centromere protein unphosphorylated form (human)
hINCENP/PhosRes-

organism-modification


PR:000070978 inner centromere protein methylated 1 (human)
hINCENP/Me:1

organism-modification


PR:000080314 inner centromere protein phosphorylated 2 (human)
hINCENP/Phos:2

organism-modification


PR:000083136 inner centromere protein cysteinylated 1 (human)
hINCENP/Cyst:1

organism-gene


PR:Q9WU62 inner centromere protein (mouse)
mINCENP

organism-sequence


PR:Q9WU62-1 inner centromere protein isoform m1 (mouse)
mINCENP/iso:m1

organism-sequence


PR:Q9WU62-2 inner centromere protein isoform m2 (mouse)
mINCENP/iso:m2

modification


PR:000035526 inner centromere protein phosphorylated 1
INCENP/Phos:1

organism-modification


PR:000035527 inner centromere protein phosphorylated 1 (human)
hINCENP/Phos:1
Yes
modification


PR:000035528 inner centromere protein unphosphorylated form
INCENP/PhosRes-

organism-modification


PR:000035529 inner centromere protein unphosphorylated form (human)
hINCENP/PhosRes-

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035527 hINCENP/Phos:1
UniProtKB:Q9NQS7, Thr-892, MOD:00047|Ser-893/Ser-894, MOD:00046		 acts_upstream_of_or_withinincreased GO:0033674 positive regulation of kinase activity relative to PR:000035529 hINCENP/PhosRes- PMID:22024163
PR:Q9NQS7 hINCENP acts_upstream_of_or_withinGO:0034501 protein localization to kinetochore PMID:17617734
GO:0034501 protein localization to kinetochore PMID:17617734
enablesGO:0005515 protein binding with PR:O15392 API4 BioGRID:BG-251075; IntAct:EBI-1555366; MINT:MINT-77928
GO:0005515 protein binding with PR:P06493 CDC2 BioGRID:BG-251075; IntAct:EBI-1555366; MINT:MINT-77928
GO:0005515 protein binding with PR:Q53HL2 CDCA8 BioGRID:BG-251075; IntAct:EBI-1555366; MINT:MINT-77928
GO:0005515 protein binding with PR:Q5FBB7 hSGO1 BioGRID:BG-251075; IntAct:EBI-1555366; MINT:MINT-77928
GO:0005515 protein binding with PR:Q71DI3 H3-clustered histone 13 (human) BioGRID:BG-251075; IntAct:EBI-1555366; MINT:MINT-77928
GO:0005515 protein binding with PR:Q96GD4 AIK2 BioGRID:BG-251075; IntAct:EBI-1555366; MINT:MINT-77928
located_inGO:0000776 kinetochore PMID:20624902
GO:0000939 inner kinetochore PMID:16760428