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Protein Ontology report - interleukin-1 receptor-like 1
PR:000008994 - http://purl.obolibrary.org/obo/PR_000008994
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008994   
  PRO nameinterleukin-1 receptor-like 1 
  Synonyms
PRO-Short-label: EXACT:IL1RL1
Gene-based: RELATED:DER4 | Ly84 | ST2 | Ste2 | T1
Other: EXACT:lymphocyte antigen 84 | protein ST2 | protein T1
  Definition"A protein that is a translation product of the human IL1RL1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 8                                        
         Modification1                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1735
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008994

interleukin-1 receptor-like 1

IL1RL1


"A protein that is a translation product of the human IL1RL1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P14719

interleukin-1 receptor-like 1 (mouse)

mIL1RL1


"An interleukin-1 receptor-like 1 that is encoded in the genome of mouse." [OMA:P14719, PRO:DNx]


organism-sequence



PR:P14719-1

interleukin-1 receptor-like 1 isoform A (mouse)

mIL1RL1/iso:A


"An interleukin-1 receptor-like 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14719-1." [PRO:DNx, UniProtKB:P14719]

Yes

organism-modification



PR:000037495

interleukin-1 receptor-like 1 isoform A, signal peptide removed form (mouse)

mIL1RL1/iso:A/SigPep-


"An interleukin-1 receptor-like 1 isoform A (mouse) that has had the signal peptide removed. UniProtKB:P14719-1, 27-567." [PMID:7883081, PMID:8131748, PRO:KRC, UniProtKB:P14719]


organism-sequence



PR:P14719-2

interleukin-1 receptor-like 1 isoform B (mouse)

mIL1RL1/iso:B


"An interleukin-1 receptor-like 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14719-2." [PRO:DNx, UniProtKB:P14719]

Yes

organism-modification



PR:000037497

interleukin-1 receptor-like 1 isoform B, signal peptide removed form (mouse)

mIL1RL1/iso:B/SigPep-


"An interleukin-1 receptor-like 1 isoform B (mouse) that has had the signal peptide removed. UniProtKB:P14719-2, 27-337." [PMID:7883081, PMID:8131748, PRO:KRC, UniProtKB:P14719]


organism-modification



PR:000044792

interleukin-1 receptor-like 1 isoform B, signal peptide removed glycosylated form (mouse)

mIL1RL1/iso:B/SigPep-/GlycoRes+


"An interleukin-1 receptor-like 1 isoform B, signal peptide removed form (mouse) that has been post-translationally modified by N-glycosylation and sialylation. UniProtKB:P14719-2, 27-337, MOD:00693." [PMID:1532358, PRO:KRC]


organism-gene



PR:Q01638

interleukin-1 receptor-like 1 (human)

hIL1RL1


"An interleukin-1 receptor-like 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q01638]


organism-sequence



PR:Q01638-1

interleukin-1 receptor-like 1 isoform A (human)

hIL1RL1/iso:A


"An interleukin-1 receptor-like 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01638-1." [PRO:DNx, UniProtKB:Q01638]


organism-sequence



PR:Q01638-2

interleukin-1 receptor-like 1 isoform B (human)

hIL1RL1/iso:B


"An interleukin-1 receptor-like 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01638-2." [PRO:DNx, UniProtKB:Q01638]


organism-modification



PR:000085985

interleukin-1 receptor-like 1 isoform B, signal peptide removed form (human)

hIL1RL1/iso:B/SigPep-


"An interleukin-1 receptor-like 1 isoform B (human) that has had the signal peptide removed. UniProtKB:Q01638-2, 19-328." [PRO:DNx, Reactome:R-HSA-8981971]


organism-sequence



PR:Q01638-3

interleukin-1 receptor-like 1 isoform C (human)

hIL1RL1/iso:C


"An interleukin-1 receptor-like 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01638-3." [PRO:DNx, UniProtKB:Q01638]


organism-sequence



PR:Q01638-4

interleukin-1 receptor-like 1 isoform h4 (human)

hIL1RL1/iso:h4


"An interleukin-1 receptor-like 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01638-4." [PRO:DNx, UniProtKB:Q01638]


organism-modification



PR:000048001

interleukin-1 receptor-like 1, signal peptide removed form (human)

hIL1RL1/SigPep-


"An interleukin-1 receptor-like 1 (human) that has had the signal peptide removed. UniProtKB:Q01638, 19-556." [PRO:DNx, Reactome:R-HSA-197594]


organism-modification



PR:000085985

interleukin-1 receptor-like 1 isoform B, signal peptide removed form (human)

hIL1RL1/iso:B/SigPep-


"An interleukin-1 receptor-like 1 isoform B (human) that has had the signal peptide removed. UniProtKB:Q01638-2, 19-328." [PRO:DNx, Reactome:R-HSA-8981971]


organism-modification



PR:000071848

interleukin-1 receptor-like 1 phosphorylated 1 (human)

hIL1RL1/Phos:1


"An interleukin-1 receptor-like 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-68 of the amino acid sequence represented by UniProtKB:Q01638-1. Example: UniProtKB:Q01638-1, Ser-68, MOD:00046." [IEDB_epitope:912048, PRO:DNx]


organism-gene



PR:Q62611

interleukin-1 receptor-like 1 (rat)

rIL1RL1


"An interleukin-1 receptor-like 1 that is encoded in the genome of rat." [OMA:Q62611, PRO:DNx]


organism-sequence



PR:Q62611-1

interleukin-1 receptor-like 1 isoform A (rat)

rIL1RL1/iso:A


"An interleukin-1 receptor-like 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62611-1." [PRO:DNx, UniProtKB:Q62611]


organism-sequence



PR:Q62611-2

interleukin-1 receptor-like 1 isoform B (rat)

rIL1RL1/iso:B


"An interleukin-1 receptor-like 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62611-2." [PRO:DNx, UniProtKB:Q62611]


modification



PR:000020295

interleukin-1 receptor-like 1, signal peptide removed form

IL1RL1/SigPep-


"An interleukin-1 receptor-like 1 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000037495

interleukin-1 receptor-like 1 isoform A, signal peptide removed form (mouse)

mIL1RL1/iso:A/SigPep-


"An interleukin-1 receptor-like 1 isoform A (mouse) that has had the signal peptide removed. UniProtKB:P14719-1, 27-567." [PMID:7883081, PMID:8131748, PRO:KRC, UniProtKB:P14719]


organism-modification



PR:000037497

interleukin-1 receptor-like 1 isoform B, signal peptide removed form (mouse)

mIL1RL1/iso:B/SigPep-


"An interleukin-1 receptor-like 1 isoform B (mouse) that has had the signal peptide removed. UniProtKB:P14719-2, 27-337." [PMID:7883081, PMID:8131748, PRO:KRC, UniProtKB:P14719]


organism-modification



PR:000044792

interleukin-1 receptor-like 1 isoform B, signal peptide removed glycosylated form (mouse)

mIL1RL1/iso:B/SigPep-/GlycoRes+


"An interleukin-1 receptor-like 1 isoform B, signal peptide removed form (mouse) that has been post-translationally modified by N-glycosylation and sialylation. UniProtKB:P14719-2, 27-337, MOD:00693." [PMID:1532358, PRO:KRC]


organism-modification



PR:000048001

interleukin-1 receptor-like 1, signal peptide removed form (human)

hIL1RL1/SigPep-


"An interleukin-1 receptor-like 1 (human) that has had the signal peptide removed. UniProtKB:Q01638, 19-556." [PRO:DNx, Reactome:R-HSA-197594]


organism-modification



PR:000085985

interleukin-1 receptor-like 1 isoform B, signal peptide removed form (human)

hIL1RL1/iso:B/SigPep-


"An interleukin-1 receptor-like 1 isoform B (human) that has had the signal peptide removed. UniProtKB:Q01638-2, 19-328." [PRO:DNx, Reactome:R-HSA-8981971]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P14719-1 mIL1RL1/iso:A enablesGO:0002113 interleukin-33 binding with PR:Q66H70 IL-33 (rat) MGI_ref:3723275; PMID:17623648
GO:0002113 interleukin-33 binding with PR:Q8BVZ5 IL-33 (mouse) MGI_ref:3723275; PMID:17623648
GO:0002114 interleukin-33 receptor activity MGI_ref:3723275; PMID:17623648
located_inGO:0009897 external side of plasma membrane MGI_ref:65300; PMID:8131748
GO:0016020 membrane MGI_ref:71218; PMID:7883081
PR:P14719-2 mIL1RL1/iso:B acts_upstream_of_or_withinGO:0043124 negative regulation of canonical NF-kappaB signal transduction MGI_ref:3723275; PMID:17623648
enablesGO:0002113 interleukin-33 binding with PR:Q8BVZ5 IL-33 (mouse) MGI_ref:3723275; PMID:17623648
located_inGO:0031012 extracellular matrix MGI_ref:71218; PMID:7883081