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Protein Ontology report - isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
PR:000008889 - http://purl.obolibrary.org/obo/PR_000008889
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008889   
  PRO nameisocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 
  Synonyms
PRO-Short-label: EXACT:IDH3A
Other: EXACT:isocitric dehydrogenase subunit alpha | NAD(+)-specific ICDH subunit alpha
  Definition"An isocitrate dehydrogenase [NAD], mitochondrial that is a translation product of the human IDH3A gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000026157 isocitrate dehydrogenase [NAD], mitochondrial
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000008889
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
IDH3A
"An isocitrate dehydrogenase [NAD], mitochondrial that is a translation product of the human IDH3A gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:P50213
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (human)
hIDH3A
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is encoded in the genome of human." [PRO:CNA]

Yes
organism-sequence


PR:P50213-1
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (human)
hIDH3A/iso:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:HJD]

organism-sequence


PR:P50213-2
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 (human)
hIDH3A/iso:2
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 that is encoded in the genome of human." [PRO:HJD]

organism-modification


PR:000047943
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, transit peptide removed form (human)
hIDH3A/TransPep-
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P50213, 28-366." [PRO:DNx, Reactome:R-HSA-70962]

organism-modification


PR:000077630
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial methylated 1 (human)
hIDH3A/Me:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (human) that has been methylated on the residue at the position equivalent to Cys-127 of the amino acid sequence represented by UniProtKB:P50213-1. Example: UniProtKB:P50213-1, Cys-127, MOD:00660." [IEDB_epitope:1059181, PRO:DNx]

organism-modification


PR:000085694
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial cysteinylated 1 (human)
hIDH3A/Cyst:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (human) that has been cysteinylated on the residue at the position equivalent to Cys-236 of the amino acid sequence represented by UniProtKB:P50213-1. Example: UniProtKB:P50213-1, Cys-236, MOD:00765." [IEDB_epitope:1061628, PRO:DNx]

organism-gene


PR:Q55BI2
isocitrate dehydrogenase [NAD] regulatory subunit A, mitochondrial (Dictyostelium discoideum)
Dicty-IDH3A
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55BI2, PRO:DNx]

organism-gene


PR:Q93714
probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (worm)
IDH3A (worm)
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is encoded in the genome of worm." [OMA:Q93714, PRO:DAN]

organism-gene


PR:Q99NA5
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (rat)
rIDH3A
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is encoded in the genome of rat." [PRO:DAN]

organism-gene


PR:Q9D6R2
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (mouse)
mIDH3A
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is encoded in the genome of mouse." [OMA:Q9D6R2, PRO:DAN, PRO:HJD]

Yes
organism-sequence


PR:Q9D6R2-1
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (mouse)
mIDH3A/iso:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
Yes
Yes
organism-sequence


PR:Q9D6R2-2
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 (mouse)
mIDH3A/iso:2
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 that is encoded in the genome of mouse." [PRO:HJD]

Yes
organism-gene


PR:Q9VWH4
probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (fruit fly)
fly-IDH3A
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is encoded in the genome of fruit fly." [OMA:Q9VWH4, PRO:DAN]

organism-sequence


PR:Q9VWH4-1
probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform D (fruit fly)
fly-IDH3A/iso:D
"A probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9VWH4-1." [PRO:DNx, UniProtKB:Q9VWH4]

organism-sequence


PR:Q9VWH4-2
probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform A (fruit fly)
fly-IDH3A/iso:A
"A probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9VWH4-2." [PRO:DNx, UniProtKB:Q9VWH4]

sequence


PR:000025352
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1
IDH3A/iso:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D6R2-1 or a 1:1 ortholog thereof." [PRO:HJD]

organism-sequence


PR:P50213-1
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (human)
hIDH3A/iso:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:HJD]

organism-sequence


PR:Q9D6R2-1
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 (mouse)
mIDH3A/iso:1
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
Yes
Yes
sequence


PR:000025353
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2
IDH3A/iso:2
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D6R2-2 or a 1:1 ortholog thereof." [PRO:DAN, PRO:HJD]

organism-sequence


PR:P50213-2
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 (human)
hIDH3A/iso:2
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 that is encoded in the genome of human." [PRO:HJD]

organism-sequence


PR:Q9D6R2-2
isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 (mouse)
mIDH3A/iso:2
"An isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform 2 that is encoded in the genome of mouse." [PRO:HJD]

Yes
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IDH3A forms found in complexes   

IDH3A Component
 Complexes
PR:P50213 hIDH3A PR:000026161 mitochondrial isocitrate dehydrogenase complex (NAD+) (human)
PR:Q9D6R2 mIDH3A PR:000026071 mitochondrial isocitrate dehydrogenase complex (NAD+) (mouse)
PR:Q9D6R2ZDASHZ1 mIDH3A/iso:1 PR:000026072 mitochondrial isocitrate dehydrogenase complex (NAD+) A (mouse)
PR:Q9D6R2ZDASHZ2 mIDH3A/iso:2 PR:000026073 mitochondrial isocitrate dehydrogenase complex (NAD+) B (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9D6R2-1 mIDH3A/iso:1 located_inGO:0005739 mitochondrion MGI_ref:3852644; PMID:18614015
GO:0005739 mitochondrion MGI_ref:3852644; PMID:18614015