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Protein Ontology report - isoleucine--tRNA ligase, cytoplasmic
PR:000008876 - http://purl.obolibrary.org/obo/PR_000008876
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000008876   
  PRO nameisoleucine--tRNA ligase, cytoplasmic 
  Synonyms
PRO-Short-label: EXACT:IARS1
Gene-based: RELATED:IARS
Other: EXACT:IRS | isoleucyl-tRNA synthetase, cytoplasmic
  Definition"A protein that is a translation product of the human IARS1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008876

isoleucine--tRNA ligase, cytoplasmic

IARS1


"A protein that is a translation product of the human IARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:F4JLM5

isoleucine--tRNA ligase, cytoplasmic (Arabidopsis thaliana)

At-IARS


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of Arabidopsis thaliana." [OMA:F4JLM5, PRO:DNx]


organism-gene



PR:O13651

isoleucine--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-)

Spom972h-IARS


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O13651, PRO:DNx]


organism-gene



PR:P09436

isoleucine--tRNA ligase, cytoplasmic (yeast)

yIARS


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of yeast." [OMA:P09436, PRO:DNx]


organism-gene



PR:P41252

isoleucine--tRNA ligase, cytoplasmic (human)

hIARS1


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:P41252-1

isoleucine--tRNA ligase, cytoplasmic isoform 1 (human)

hIARS/iso:1


"An isoleucine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000070706

isoleucine--tRNA ligase, cytoplasmic deaminated 1 (human)

hIARS1/Deam:1


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been deaminated on the residue at the position equivalent to Gln-1139 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Gln-1139, MOD:00685." [IEDB_epitope:1367501, PRO:DNx]


organism-modification



PR:000074363

isoleucine--tRNA ligase, cytoplasmic cysteinylated 1 (human)

hIARS1/Cyst:1


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been cysteinylated on the residue at the position equivalent to Cys-433 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Cys-433, MOD:00765." [IEDB_epitope:1577865, PRO:DNx]


organism-modification



PR:000075908

isoleucine--tRNA ligase, cytoplasmic hydroxylated 1 (human)

hIARS1/Hy:1


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been hydroxylated on the residue at the position equivalent to Trp-733 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Trp-733, MOD:01622." [IEDB_epitope:1317097, PRO:DNx]


organism-modification



PR:000080610

isoleucine--tRNA ligase, cytoplasmic methylated 1 (human)

hIARS1/Me:1


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-336 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Cys-336, MOD:00660." [IEDB_epitope:1046469, PRO:DNx]


organism-modification



PR:000081743

isoleucine--tRNA ligase, cytoplasmic cysteinylated 2 (human)

hIARS1/Cyst:2


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been cysteinylated on the residue at the position equivalent to Cys-1080 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Cys-1080, MOD:00765." [IEDB_epitope:1587419, PRO:DNx]


organism-modification



PR:000082039

isoleucine--tRNA ligase, cytoplasmic deaminated 2 (human)

hIARS1/Deam:2


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been deaminated on the residue at the position equivalent to Asn-629 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Asn-629, MOD:00684." [IEDB_epitope:1363581, PRO:DNx]


organism-modification



PR:000083317

isoleucine--tRNA ligase, cytoplasmic cysteinylated 3 (human)

hIARS1/Cyst:3


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been cysteinylated on the residue at the position equivalent to Cys-120 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Cys-120, MOD:00765." [IEDB_epitope:1582662, PRO:DNx]


organism-modification



PR:000084395

isoleucine--tRNA ligase, cytoplasmic methylated 2 (human)

hIARS1/Me:2


"An isoleucine--tRNA ligase, cytoplasmic (human) that has been methylated on the residue at the position equivalent to Cys-526 of the amino acid sequence represented by UniProtKB:P41252. UniProtKB:P41252, Cys-526, MOD:00660." [IEDB_epitope:1042149, PRO:DNx]


organism-gene



PR:Q21926

isoleucine--tRNA ligase, cytoplasmic (worm)

IARS (worm)


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of worm." [OMA:Q21926, PRO:DNx]


organism-gene



PR:Q54YD4

probable isoleucine--tRNA ligase, cytoplasmic (Dictyostelium discoideum)

Dicty-IARS


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54YD4, PRO:DNx]


organism-gene



PR:Q8BU30

isoleucine--tRNA ligase, cytoplasmic (mouse)

mIARS


"An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q8BU30, PRO:DNx]


organism-sequence



PR:Q8BU30-1

isoleucine--tRNA ligase, cytoplasmic isoform 1 (mouse)

mIARS/iso:1


"An isoleucine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000039423

isoleucine--tRNA ligase, cytoplasmic isoform 1

IARS/iso:1


"An isoleucine--tRNA ligase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41252-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P41252-1

isoleucine--tRNA ligase, cytoplasmic isoform 1 (human)

hIARS/iso:1


"An isoleucine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q8BU30-1

isoleucine--tRNA ligase, cytoplasmic isoform 1 (mouse)

mIARS/iso:1


"An isoleucine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


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IARS1 forms found in complexes   

IARS1 Component
Complexes
PR:P41252 hIARS1 PR:000027407 aminoacyl-tRNA synthetase multienzyme complex (human)