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Protein Ontology report - heat shock factor protein 1
PR:000008790 - http://purl.obolibrary.org/obo/PR_000008790
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008790   
  PRO nameheat shock factor protein 1 
  Synonyms
PRO-Short-label: EXACT:HSF1
Gene-based: RELATED:HSTF1
Other: EXACT:heat shock transcription factor 1 | HSF 1 | HSTF 1
  Definition"A protein that is a translation product of the human HSF1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification2                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000008790
heat shock factor protein 1
HSF1
"A protein that is a translation product of the human HSF1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P38529
heat shock factor protein 1 (chicken)
chick-HSF1
"A heat shock factor protein 1 that is encoded in the genome of chicken." [OMA:P38529, PRO:DNx]

organism-gene


PR:P38532
heat shock factor protein 1 (mouse)
mHSF1
"A heat shock factor protein 1 that is encoded in the genome of mouse." [OMA:P38532, PRO:DNx]

organism-sequence


PR:P38532-1
heat shock factor protein 1 isoform Long (mouse)
mHSF1/iso:Long
"A heat shock factor protein 1 isoform Long that is encoded in the genome of mouse." [PRO:CNA]

organism-modification


PR:000025794
heat shock factor protein 1 isoform Long phosphorylated 2 (mouse)
mHSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long phosphorylated 2 in mouse. UniProtKB:P38532-1, Ser-303/Ser-307, MOD:00046." [PMID:19131326]

organism-sequence


PR:P38532-2
heat shock factor protein 1 isoform m1 (mouse)
mHSF1/iso:m1
"A heat shock factor protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P38532-2." [PRO:DNx, UniProtKB:P38532]

organism-gene


PR:Q00613
heat shock factor protein 1 (human)
hHSF1
"A heat shock factor protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q00613]

organism-sequence


PR:Q00613-1
heat shock factor protein 1 isoform Long (human)
hHSF1/iso:Long
"A heat shock factor protein 1 isoform Long that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000025723
heat shock factor protein 1 isoform Long phosphorylated 1 (human)
hHSF1/iso:Long/Phos:1
"A heat shock factor protein 1 isoform Long phosphorylated 1 in human. UniProtKB:Q00613-1, Ser-121, MOD:00046." [PMID:16278218, PRO:JAN]
Yes
organism-modification


PR:000025725
heat shock factor protein 1 isoform Long phosphorylated 2 (human)
hHSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long phosphorylated 2 in human. UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046." [PMID:12917326, PMID:9121459]
Yes
organism-sequence


PR:Q00613-2
heat shock factor protein 1 isoform Short (human)
hHSF1/iso:Short
"A heat shock factor protein 1 isoform Short that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000045863
heat shock factor protein 1 phosphorylated 1 (human)
hHSF1/Phos:1
"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-142 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Thr-142, MOD:00047." [iPTMnet:Q00613, PMID:12659875]

organism-modification


PR:000047906
heat shock factor protein 1 phosphorylated 3 (human)
hHSF1/Phos:3
"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-303 of the amino acid sequence represented by UniProtKB:Q00613. UniProtKB:Q00613, Ser-303, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793927]

organism-modification


PR:000047907
heat shock factor protein 1 phosphorylated 2 (human)
hHSF1/Phos:2
"A heat shock factor protein 1 (human) that has been post-translationally modified to include phosphoserine at positions 303 and 307 of the amino acid sequence represented by UniProtKB:Q00613. UniProtKB:Q00613, Ser-303/Ser-307, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793922]

organism-modification


PR:000047908
heat shock factor protein 1 phosphorylated 4 (human)
hHSF1/Phos:4
"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-307 of the amino acid sequence represented by UniProtKB:Q00613. UniProtKB:Q00613, Ser-307, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793929]

organism-modification


PR:000063815
heat shock factor protein 1 phosphorylated 5 (human)
hHSF1/Phos:5
"A heat shock factor protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-121 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Ser-121, MOD:00046." [PRO:DNx, Reactome:R-HSA-4793906]

organism-modification


PR:000069043
heat shock factor protein 1 methylated 1 (human)
hHSF1/Me:1
"A heat shock factor protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-378 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Cys-378, MOD:00660." [IEDB_epitope:1056412, PRO:DNx]

organism-modification


PR:000085520
heat shock factor protein 1 methylated 2 (human)
hHSF1/Me:2
"A heat shock factor protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-103 of the amino acid sequence represented by UniProtKB:Q00613-1. Example: UniProtKB:Q00613-1, Cys-103, MOD:00660." [IEDB_epitope:1053538, IEDB_epitope:1053539, PRO:DNx]

sequence


PR:000025717
heat shock factor protein 1 isoform Long
HSF1/iso:Long
"A heat shock factor protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00613-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P38532-1
heat shock factor protein 1 isoform Long (mouse)
mHSF1/iso:Long
"A heat shock factor protein 1 isoform Long that is encoded in the genome of mouse." [PRO:CNA]

organism-modification


PR:000025794
heat shock factor protein 1 isoform Long phosphorylated 2 (mouse)
mHSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long phosphorylated 2 in mouse. UniProtKB:P38532-1, Ser-303/Ser-307, MOD:00046." [PMID:19131326]

organism-sequence


PR:Q00613-1
heat shock factor protein 1 isoform Long (human)
hHSF1/iso:Long
"A heat shock factor protein 1 isoform Long that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000025723
heat shock factor protein 1 isoform Long phosphorylated 1 (human)
hHSF1/iso:Long/Phos:1
"A heat shock factor protein 1 isoform Long phosphorylated 1 in human. UniProtKB:Q00613-1, Ser-121, MOD:00046." [PMID:16278218, PRO:JAN]
Yes
organism-modification


PR:000025725
heat shock factor protein 1 isoform Long phosphorylated 2 (human)
hHSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long phosphorylated 2 in human. UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046." [PMID:12917326, PMID:9121459]
Yes
modification


PR:000025722
heat shock factor protein 1 isoform Long phosphorylated 1
HSF1/iso:Long/Phos:1
"A heat shock factor protein 1 isoform Long that has been phosphorylated by MAPK-activated protein kinase 2. Example: UniProtKB:Q00613-1, Ser-121, MOD:00046." [PMID:16278218, PRO:DAN, PRO:JAN]

organism-modification


PR:000025723
heat shock factor protein 1 isoform Long phosphorylated 1 (human)
hHSF1/iso:Long/Phos:1
"A heat shock factor protein 1 isoform Long phosphorylated 1 in human. UniProtKB:Q00613-1, Ser-121, MOD:00046." [PMID:16278218, PRO:JAN]
Yes
modification


PR:000025724
heat shock factor protein 1 isoform Long phosphorylated 2
HSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long that has been phosphorylated at Ser residues distal to the transcriptional activation domain. Example: UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046." [PMID:9121459]

organism-modification


PR:000025725
heat shock factor protein 1 isoform Long phosphorylated 2 (human)
hHSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long phosphorylated 2 in human. UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046." [PMID:12917326, PMID:9121459]
Yes
organism-modification


PR:000025794
heat shock factor protein 1 isoform Long phosphorylated 2 (mouse)
mHSF1/iso:Long/Phos:2
"A heat shock factor protein 1 isoform Long phosphorylated 2 in mouse. UniProtKB:P38532-1, Ser-303/Ser-307, MOD:00046." [PMID:19131326]

sequence


PR:000025719
heat shock factor protein 1 isoform Short
HSF1/iso:Short
"A heat shock factor protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00613-2 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:Q00613-2
heat shock factor protein 1 isoform Short (human)
hHSF1/iso:Short
"A heat shock factor protein 1 isoform Short that is encoded in the genome of human." [PRO:CNA]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025723 hHSF1/iso:Long/Phos:1
UniProtKB:Q00613-1, Ser-121, MOD:00046		 enablesNOT GO:0000976 transcription cis-regulatory region binding PMID:16278218
GO:0005515 protein binding with PR:P08238 heat shock 84 kDa (human) PMID:16278218
GO:0005515 protein binding PMID:16278218
PR:000025725 hHSF1/iso:Long/Phos:2
UniProtKB:Q00613-1, Ser-303/Ser-307, MOD:00046		 enablesGO:0071889 14-3-3 protein binding with PR:P62258 14-3-3E (human) PMID:12917326
located_inGO:0005737 cytoplasm PMID:12917326