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Protein Ontology report - 3-hydroxy-3-methylglutaryl-coenzyme A reductase
PR:000008636 - http://purl.obolibrary.org/obo/PR_000008636
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000008636   
  PRO name3-hydroxy-3-methylglutaryl-coenzyme A reductase 
  Synonyms
PRO-Short-label: EXACT:HMGCR
Other: EXACT:HMG-CoA reductase
  Definition"A protein that is a translation product of the human HMGCR gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:639
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000008636
3-hydroxy-3-methylglutaryl-coenzyme A reductase
HMGCR
"A protein that is a translation product of the human HMGCR gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P04035
3-hydroxy-3-methylglutaryl-coenzyme A reductase (human)
hHMGCR
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04035]

organism-sequence


PR:P04035-1
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform h1 (human)
hHMGCR/iso:h1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04035-1." [PRO:DNx, UniProtKB:P04035]

organism-sequence


PR:P04035-2
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform h2 (human)
hHMGCR/iso:h2
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04035-2." [PRO:DNx, UniProtKB:P04035]

organism-sequence


PR:P04035-3
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform h3 (human)
hHMGCR/iso:h3
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04035-3." [PRO:DNx, UniProtKB:P04035]

organism-modification


PR:000065138
3-hydroxy-3-methylglutaryl-coenzyme A reductase phosphorylated 1 (human)
hHMGCR/Phos:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been phosphorylated on the residue at the position equivalent to Ser-271 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Ser-271, MOD:00046." [IEDB_epitope:2146986, PRO:DNx]

organism-modification


PR:000066152
3-hydroxy-3-methylglutaryl-coenzyme A reductase methylated 1 (human)
hHMGCR/Me:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been methylated on the residue at the position equivalent to Cys-70 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-70, MOD:00660." [IEDB_epitope:1055386, PRO:DNx]

organism-modification


PR:000066447
3-hydroxy-3-methylglutaryl-coenzyme A reductase cysteinylated 1 (human)
hHMGCR/Cyst:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been cysteinylated on the residue at the position equivalent to Cys-448 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-448, MOD:00765." [IEDB_epitope:1568586, PRO:DNx]

organism-modification


PR:000072330
3-hydroxy-3-methylglutaryl-coenzyme A reductase phosphorylated 2 (human)
hHMGCR/Phos:2
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been phosphorylated on the residue at the position equivalent to Ser-298 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Ser-298, MOD:00046." [IEDB_epitope:2147416, PRO:DNx]

organism-modification


PR:000076075
3-hydroxy-3-methylglutaryl-coenzyme A reductase cysteinylated 2 (human)
hHMGCR/Cyst:2
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been cysteinylated on the residue at the position equivalent to Cys-215 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-215, MOD:00765." [IEDB_epitope:1336724, PRO:DNx]

organism-modification


PR:000078711
3-hydroxy-3-methylglutaryl-coenzyme A reductase cysteinylated 3 (human)
hHMGCR/Cyst:3
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been cysteinylated on the residue at the position equivalent to Cys-795 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-795, MOD:00765." [IEDB_epitope:1564888, PRO:DNx]

organism-modification


PR:000080128
3-hydroxy-3-methylglutaryl-coenzyme A reductase methylated 2 (human)
hHMGCR/Me:2
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been methylated on the residue at the position equivalent to Cys-448 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-448, MOD:00660." [IEDB_epitope:1008866, PRO:DNx]

organism-modification


PR:000080310
3-hydroxy-3-methylglutaryl-coenzyme A reductase cysteinylated 4 (human)
hHMGCR/Cyst:4
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been cysteinylated on the residue at the position equivalent to Cys-545 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-545, MOD:00765." [IEDB_epitope:924898, PRO:DNx]

organism-modification


PR:000081968
3-hydroxy-3-methylglutaryl-coenzyme A reductase methylated 3 (human)
hHMGCR/Me:3
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been methylated on the residue at the position equivalent to Cys-215 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-215, MOD:00660." [IEDB_epitope:1053829, PRO:DNx]

organism-modification


PR:000082976
3-hydroxy-3-methylglutaryl-coenzyme A reductase cysteinylated 5 (human)
hHMGCR/Cyst:5
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase (human) that has been cysteinylated on the residue at the position equivalent to Cys-176 of the amino acid sequence represented by UniProtKB:P04035-1. Example: UniProtKB:P04035-1, Cys-176, MOD:00765." [IEDB_epitope:1336383, PRO:DNx]

organism-gene


PR:P14773
3-hydroxy-3-methylglutaryl-coenzyme A reductase (fruit fly)
fly-HMGCR
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of fruit fly." [OMA:P14773, PRO:DNx]

organism-gene


PR:P51639
3-hydroxy-3-methylglutaryl-coenzyme A reductase (rat)
rHMGCR
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of rat." [OMA:P51639, PRO:DNx]

organism-sequence


PR:P51639-1
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 (rat)
rHMGCR/iso:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:Q01237
3-hydroxy-3-methylglutaryl-coenzyme A reductase (mouse)
mHMGCR
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of mouse." [OMA:Q01237, PRO:DNx]

organism-sequence


PR:Q01237-1
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 (mouse)
mHMGCR/iso:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:Q10283
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Schizosaccharomyces pombe 972h-)
Spom972h-HMGCR
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR10572:SF0, PRO:DNx]

organism-gene


PR:Q19207
3-hydroxy-3-methylglutaryl coenzyme A reductase (worm)
HMGCR (worm)
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of worm." [PANTHER:PTHR10572:SF0, PRO:DNx]

sequence


PR:000040224
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1
HMGCR/iso:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01237-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P51639-1
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 (rat)
rHMGCR/iso:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q01237-1
3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 (mouse)
mHMGCR/iso:1
"A 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]