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Protein Ontology report - histone deacetylase 4
PR:000008483 - http://purl.obolibrary.org/obo/PR_000008483
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008483   
  PRO namehistone deacetylase 4 
  Synonyms
PRO-Short-label: EXACT:HDAC4
Gene-based: RELATED:KIAA0288
Other: EXACT:HD4
  Definition"A protein that is a translation product of the human HDAC4 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2659
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008483

histone deacetylase 4

HDAC4


"A protein that is a translation product of the human HDAC4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P56524

histone deacetylase 4 (human)

hHDAC4


"A histone deacetylase 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P56524]


organism-sequence



PR:P56524-1

histone deacetylase 4 isoform 1 (human)

hHDAC4/iso:1


"A histone deacetylase 4 isoform 1 that is encoded in the genome of human." [PRO:ALI]


organism-modification



PR:000029002

histone deacetylase 4 isoform 1 phosphorylated 1 (human)

hHDAC4/iso:1/Phos:1


"A histone deacetylase 4 isoform 1 phosphorylated 1 in human. UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046." [PMID:17179159, PRO:ALI]

Yes

organism-sequence



PR:P56524-2

histone deacetylase 4 isoform h2 (human)

hHDAC4/iso:h2


"A histone deacetylase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56524-2." [PRO:DNx, UniProtKB:P56524]


organism-modification



PR:000064821

histone deacetylase 4 sumoylated 1 (human)

hHDAC4/Sumo:1


"A histone deacetylase 4 (human) that has been sumoylated on the residue at the position equivalent to Lys-559 of the amino acid sequence represented by UniProtKB:P56524-1. Example: UniProtKB:P56524-1, Lys-559, MOD:01149." [PRO:DNx, Reactome:R-HSA-4616016, Reactome:R-HSA-4616029]


organism-modification



PR:000077092

histone deacetylase 4 phosphorylated 1 (human)

hHDAC4/Phos:1


"A histone deacetylase 4 (human) that has been phosphorylated on the residue at the position equivalent to Ser-266 of the amino acid sequence represented by UniProtKB:P56524-1. Example: UniProtKB:P56524-1, Ser-266, MOD:00046." [IEDB_epitope:1369776, PRO:DNx]


organism-gene



PR:P83038

histone deacetylase 4 (chicken)

chick-HDAC4


"A histone deacetylase 4 that is encoded in the genome of chicken." [OMA:P83038, PRO:DNx]


organism-gene



PR:Q6NZM9

histone deacetylase 4 (mouse)

mHDAC4


"A histone deacetylase 4 that is encoded in the genome of mouse." [OMA:Q6NZM9, PRO:DNx]


organism-sequence



PR:Q6NZM9-1

histone deacetylase 4 isoform m1 (mouse)

mHDAC4/iso:m1


"A histone deacetylase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NZM9-1." [PRO:DNx, UniProtKB:Q6NZM9]


organism-sequence



PR:Q6NZM9-2

histone deacetylase 4 isoform m2 (mouse)

mHDAC4/iso:m2


"A histone deacetylase 4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6NZM9-2." [PRO:DNx, UniProtKB:Q6NZM9]


organism-gene



PR:Q99P99

histone deacetylase 4 (rat)

rHDAC4


"A histone deacetylase 4 that is encoded in the genome of rat." [OMA:Q99P99, PRO:DNx]


sequence



PR:000028999

histone deacetylase 4 isoform 1

HDAC4/iso:1


"A histone deacetylase 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56524-1 or a 1:1 ortholog thereof." [PMID:17179159, PRO:ALI]


organism-sequence



PR:P56524-1

histone deacetylase 4 isoform 1 (human)

hHDAC4/iso:1


"A histone deacetylase 4 isoform 1 that is encoded in the genome of human." [PRO:ALI]


organism-modification



PR:000029002

histone deacetylase 4 isoform 1 phosphorylated 1 (human)

hHDAC4/iso:1/Phos:1


"A histone deacetylase 4 isoform 1 phosphorylated 1 in human. UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046." [PMID:17179159, PRO:ALI]

Yes

modification



PR:000029001

histone deacetylase 4 isoform 1 phosphorylated 1

HDAC4/iso:1/Phos:1


"A histone deacetylase 4 isoform 1 that has been phosphorylated on Ser residues as a result of the activation of the CAMK2D isoform delta 3 (also known as delta B) in cardiac cells. Example: UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046." [PMID:17179159, PRO:ALI]


organism-modification



PR:000029002

histone deacetylase 4 isoform 1 phosphorylated 1 (human)

hHDAC4/iso:1/Phos:1


"A histone deacetylase 4 isoform 1 phosphorylated 1 in human. UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046." [PMID:17179159, PRO:ALI]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000029002 hHDAC4/iso:1/Phos:1
UniProtKB:P56524-1, Ser-210/Ser-246, MOD:00046
enablesGO:0071889 14-3-3 protein binding PMID:17179159
located_inGO:0005737 cytoplasm PMID:17179159