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Protein Ontology report - tyrosine-protein kinase HCK
PR:000008473 - http://purl.obolibrary.org/obo/PR_000008473
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000008473   
  PRO nametyrosine-protein kinase HCK 
  Synonyms
PRO-Short-label: EXACT:HCK
Other: EXACT:B-cell/myeloid kinase | BMK | hematopoietic cell kinase | hemopoietic cell kinase | p56-HCK/p59-HCK | p59-HCK/p60-HCK
  Definition"A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human HCK gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000002997 proto-oncogene SRC-like tyrosine-protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 8                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2032
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000008473
tyrosine-protein kinase HCK
HCK
"A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human HCK gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P08103
tyrosine-protein kinase HCK (mouse)
mHCK
"A tyrosine-protein kinase HCK that is encoded in the genome of mouse." [OMA:P08103, PRO:DNx]

organism-sequence


PR:P08103-1
tyrosine-protein kinase HCK isoform 1 (mouse)
mHCK/iso:1
"A tyrosine-protein kinase HCK isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P08103-2
tyrosine-protein kinase HCK isoform 2 (mouse)
mHCK/iso:2
"A tyrosine-protein kinase HCK isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:P08631
tyrosine-protein kinase HCK (human)
hHCK
"A tyrosine-protein kinase HCK that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08631]

organism-sequence


PR:P08631-1
tyrosine-protein kinase HCK isoform h1 (human)
hHCK/iso:h1
"A tyrosine-protein kinase HCK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08631-1." [PRO:DNx, UniProtKB:P08631]

organism-sequence


PR:P08631-2
tyrosine-protein kinase HCK isoform h2 (human)
hHCK/iso:h2
"A tyrosine-protein kinase HCK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08631-2." [PRO:DNx, UniProtKB:P08631]

organism-sequence


PR:P08631-3
tyrosine-protein kinase HCK isoform h3 (human)
hHCK/iso:h3
"A tyrosine-protein kinase HCK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08631-3." [PRO:DNx, UniProtKB:P08631]

organism-sequence


PR:P08631-4
tyrosine-protein kinase HCK isoform h4 (human)
hHCK/iso:h4
"A tyrosine-protein kinase HCK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08631-4." [PRO:DNx, UniProtKB:P08631]

organism-modification


PR:000025889
tyrosine-protein kinase HCK phosphorylated 1 (human)
hHCK/Phos:1
"A tyrosine-protein kinase HCK phosphorylated 1 in human. UniProtKB:P08631, Tyr-522, MOD:00048." [OCA:JP, PMID:10360180]

organism-modification


PR:000047689
tyrosine-protein kinase HCK, initiator methionine removed form (human)
hHCK/InitMet-
"A tyrosine-protein kinase HCK (human) that has had the initiator methionine removed. UniProtKB:P08631, 2-526." [PRO:DNx, Reactome:R-HSA-167708]

organism-modification


PR:000064050
tyrosine-protein kinase HCK phosphorylated form (human)
hHCK/PhosRes+
"A tyrosine-protein kinase HCK (human) that includes at least one phosphorylated residue. UniProtKB:P08631, MOD:00696." [PRO:DNx, Reactome:R-HSA-9676060]

organism-modification


PR:000080597
tyrosine-protein kinase HCK glutathionylated 1 (human)
hHCK/SGlt:1
"A tyrosine-protein kinase HCK (human) that has been glutathionylated on the residue at the position equivalent to Cys-48 of the amino acid sequence represented by UniProtKB:P08631-1. Example: UniProtKB:P08631-1, Cys-48, MOD:00234." [IEDB_epitope:422740, PRO:DNx]

organism-gene


PR:P50545
tyrosine-protein kinase HCK (rat)
rHCK
"A tyrosine-protein kinase HCK that is encoded in the genome of rat." [OMA:P50545, PRO:DNx]

organism-sequence


PR:P50545-1
tyrosine-protein kinase HCK isoform 1 (rat)
rHCK/iso:1
"A tyrosine-protein kinase HCK isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:P50545-2
tyrosine-protein kinase HCK isoform 2 (rat)
rHCK/iso:2
"A tyrosine-protein kinase HCK isoform 2 that is encoded in the genome of rat." [PRO:DNx]

sequence


PR:000038730
tyrosine-protein kinase HCK isoform 1
HCK/iso:1
"A tyrosine-protein kinase HCK that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08103-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P08103-1
tyrosine-protein kinase HCK isoform 1 (mouse)
mHCK/iso:1
"A tyrosine-protein kinase HCK isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P50545-1
tyrosine-protein kinase HCK isoform 1 (rat)
rHCK/iso:1
"A tyrosine-protein kinase HCK isoform 1 that is encoded in the genome of rat." [PRO:DNx]

sequence


PR:000038731
tyrosine-protein kinase HCK isoform 2
HCK/iso:2
"A tyrosine-protein kinase HCK that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08103-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P08103-2
tyrosine-protein kinase HCK isoform 2 (mouse)
mHCK/iso:2
"A tyrosine-protein kinase HCK isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P50545-2
tyrosine-protein kinase HCK isoform 2 (rat)
rHCK/iso:2
"A tyrosine-protein kinase HCK isoform 2 that is encoded in the genome of rat." [PRO:DNx]

modification


PR:000025888
tyrosine-protein kinase HCK phosphorylated 1
HCK/Phos:1
"A tyrosine-protein kinase HCK that has been phosphorylated on the residue at the position equivalent to Tyr-522 of the amino acid sequence represented by UniProtKB:P08631. Example: UniProtKB:P08631, Tyr-522, MOD:00048." [PRO:CNA, PRO:DAN]

organism-modification


PR:000025889
tyrosine-protein kinase HCK phosphorylated 1 (human)
hHCK/Phos:1
"A tyrosine-protein kinase HCK phosphorylated 1 in human. UniProtKB:P08631, Tyr-522, MOD:00048." [OCA:JP, PMID:10360180]