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Protein Ontology report - beta-globin
PR:000008457 - http://purl.obolibrary.org/obo/PR_000008457
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000008457   
  PRO namebeta-globin 
  Synonyms
PRO-Short-label: EXACT:b-globin
  Definition"A hemoglobin subunit that is a translation product of the human HBB gene, a 1:1 ortholog thereof, or pro-orthologs thereof." [PRO:DAN] 
  PRO Categorygene 
  ParentPR:000050467 hemoglobin subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene6                                                  Organism-Gene 8                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification8                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008457

beta-globin

b-globin


"A hemoglobin subunit that is a translation product of the human HBB gene, a 1:1 ortholog thereof, or pro-orthologs thereof." [PRO:DAN]


gene



PR:000008857

hemoglobin subunit beta-1

Hbb-b1


"A beta-globin that is a translation product of the mouse Hbb-b1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P02088

hemoglobin subunit beta-1 (mouse)

mHbb-b1


"A hemoglobin subunit beta-1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P02088]


modification



PR:000020222

hemoglobin subunit beta-1, initiator methionine removed form

Hbb-b1/InitMet-


"A hemoglobin subunit beta-1 that has had the initiator methionine removed." [PRO:DNx]


gene



PR:000008858

hemoglobin subunit beta-2

Hbb-b2


"A beta-globin that is a translation product of the mouse Hbb-b2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P02089

hemoglobin subunit beta-2 (mouse)

mHbb-b2


"A hemoglobin subunit beta-2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P02089]


organism-modification



PR:000071071

hemoglobin subunit beta-2 deaminated 1 (mouse)

mHbb-b2/Deam:1


"A hemoglobin subunit beta-2 (mouse) that has been deaminated on the residue at the position equivalent to Asn-73 of the amino acid sequence represented by UniProtKB:P02089. UniProtKB:P02089, Asn-73, MOD:00684." [IEDB_epitope:1395106, PRO:DNx]


organism-gene



PR:P11517

hemoglobin subunit beta-2 (rat)

rHbb-b2


"A hemoglobin subunit beta-2 that is encoded in the genome of rat." [PRO:DAN, UniProtKB:P11517]


modification



PR:000020223

hemoglobin subunit beta-2, initiator methionine removed form

Hbb-b2/InitMet-


"A hemoglobin subunit beta-2 that has had the initiator methionine removed." [PRO:DNx]


gene



PR:000008859

hemoglobin subunit beta-H0

Hbb-bh0


"A beta-globin that is a translation product of the mouse Hbb-bh0 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P04443

hemoglobin subunit beta-H0 (mouse)

mHbb-bh0


"A hemoglobin subunit beta-H0 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P04443]


modification



PR:000020224

hemoglobin subunit beta-H0, initiator methionine removed form

Hbb-bh0/InitMet-


"A hemoglobin subunit beta-H0 that has had the initiator methionine removed." [PRO:DNx]


gene



PR:000008860

hemoglobin subunit beta-H1

Hbb-bh1


"A beta-globin that is a translation product of the mouse Hbb-bh1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P04444

hemoglobin subunit beta-H1 (mouse)

mHbb-bh1


"A hemoglobin subunit beta-H1 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P04444]


modification



PR:000020225

hemoglobin subunit beta-H1, initiator methionine removed form

Hbb-bh1/InitMet-


"A hemoglobin subunit beta-H1 that has had the initiator methionine removed." [PRO:DNx]


gene



PR:000050026

hemoglobin subunit beta

HBB


"A beta-globin that is a translation product of the human HBB gene or a 1:1 ortholog thereof." [PRO:DAN]


organism-gene



PR:P02112

hemoglobin subunit beta (chicken)

chick-HBB


"A hemoglobin subunit beta that is a translation product of the HBB gene in chicken." [PRO:DAN, UniProtKB:P02112]


organism-gene



PR:P68871

hemoglobin subunit beta (human)

hHBB


"A hemoglobin subunit beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P68871]


organism-modification



PR:000047681

hemoglobin subunit beta, initiator methionine removed form (human)

hHBB/InitMet-


"A hemoglobin subunit beta (human) that has had the initiator methionine removed. UniProtKB:P68871, 2-147." [PRO:DNx, Reactome:R-HSA-1008196, Reactome:R-HSA-2168872, Reactome:R-HSA-2230936]


organism-modification



PR:000061871

hemoglobin subunit beta, initiator methionine removed carboxylated and protonated 1 (human)

hHBB/InitMet-/Cbxprot:1


"A hemoglobin subunit beta (human) that has had the initiator methionine removed, that has been carboxylated on the residue at the position equivalent to Val-2 of the amino acid sequence represented by UniProtKB:P68871, and that includes at least one protonated residue. UniProtKB:P68871, 2-147, Val-2, MOD:01874|MOD:01699." [PRO:DNx, Reactome:R-HSA-1237013]


organism-modification



PR:000056675

hemoglobin subunit beta O-glycosylated 1 (human)

hHBB/OGlyco:1


"A hemoglobin subunit beta (human) that has been O-glycosylated at the residue equivalent to Ser-45 of the amino acid sequence represented by UniProtKB:P68871-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P68871-1, Ser-45, MOD:00002~GNO:G27391WQ." [GlyGen:P68871-1, PMID:30459171, PRO:DNx]


modification



PR:000020114

hemoglobin subunit beta, initiator methionine removed form

HBB/InitMet-


"A hemoglobin subunit beta that has had the initiator methionine removed." [PRO:DNx]


Yes
modification



PR:000050468

hemoglobin subunit beta N-1-deoxyfructosylated 1

HBB/InitMet-/dFruc:1


"A hemoglobin subunit beta, initiator methionine removed form that has been N-1-deoxyfructosylated at the position equivalent to Val-2 of the sequence represented by UniProtKB:P68871-1 or a 1:1 ortholog thereof." [PRO:DAN]


Yes
modification



PR:000060267

hemoglobin subunit beta, initiator methionine removed carbon dioxide bound form

HBB/InitMet-/carbamino


"A hemoglobin subunit beta, initiator methionine removed form that has formed a carbamate with carbon dioxide at the position equivalent to Val-2 of the sequence represented by UniProtKB:P68871-1 or a 1:1 ortholog thereof." [PRO:DAN]


Yes
organism-modification



PR:000047681

hemoglobin subunit beta, initiator methionine removed form (human)

hHBB/InitMet-


"A hemoglobin subunit beta (human) that has had the initiator methionine removed. UniProtKB:P68871, 2-147." [PRO:DNx, Reactome:R-HSA-1008196, Reactome:R-HSA-2168872, Reactome:R-HSA-2230936]


organism-modification



PR:000061871

hemoglobin subunit beta, initiator methionine removed carboxylated and protonated 1 (human)

hHBB/InitMet-/Cbxprot:1


"A hemoglobin subunit beta (human) that has had the initiator methionine removed, that has been carboxylated on the residue at the position equivalent to Val-2 of the amino acid sequence represented by UniProtKB:P68871, and that includes at least one protonated residue. UniProtKB:P68871, 2-147, Val-2, MOD:01874|MOD:01699." [PRO:DNx, Reactome:R-HSA-1237013]


modification



PR:000020115

hemoglobin subunit beta proteolytic cleavage product

HBB/ClvPrd


"A hemoglobin subunit beta that has been processed by proteolytic cleavage." [PRO:DNx]


organism-gene



PR:P02091

hemoglobin subunit beta-1 (rat)

rHbb-b1


"A beta-globin that is a translation product of the Hbb gene in rat." [PRO:DAN, UniProtKB:P02091]


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b-globin forms found in complexes   

b-globin Component
Complexes
PR:000020114 HBB/InitMet- PR:000050469 hemoglobin A1c
PR:000060250 methemoglobin
PR:000060251 carboxyhemoglobin
PR:000060254 oxyhemoglobin
PR:000060255 deoxyhemoglobin
PR:000050468 HBB/InitMet-/dFruc:1 PR:000050469 hemoglobin A1c
PR:000060267 HBB/InitMet-/carbamino PR:000060252 carbaminohemoglobin