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Protein Ontology report - gap junction alpha-1 protein
PR:000008373 - http://purl.obolibrary.org/obo/PR_000008373
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000008373   
  PRO namegap junction alpha-1 protein 
  Synonyms
PRO-Short-label: EXACT:GJA1
Gene-based: RELATED:Cxn-43 | GJAL
Other: EXACT:connexin-43 | Cx43 | gap junction 43 kDa heart protein
  Definition"A connexin protein that is a translation product of the human GJA1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000044679 connexin protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:728
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000008373

gap junction alpha-1 protein

GJA1


"A connexin protein that is a translation product of the human GJA1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O57474

gap junction alpha-1 protein (zebrafish)

z-GJA1


"A gap junction alpha-1 protein that is encoded in the genome of zebrafish." [OMA:O57474, PRO:DNx]


organism-sequence



PR:O57474-1

gap junction alpha-1 protein isoform 1 (zebrafish)

z-GJA1/iso:1


"A gap junction alpha-1 protein (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O57474-1." [PRO:DNx, UniProtKB:O57474]


organism-sequence



PR:O57474-2

gap junction alpha-1 protein isoform 2 (zebrafish)

z-GJA1/iso:2


"A gap junction alpha-1 protein (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O57474-2." [PRO:DNx, UniProtKB:O57474]


organism-sequence



PR:O57474-3

gap junction alpha-1 protein isoform 3 (zebrafish)

z-GJA1/iso:3


"A gap junction alpha-1 protein (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O57474-3." [PRO:DNx, UniProtKB:O57474]


organism-gene



PR:P08050

gap junction alpha-1 protein (rat)

rGJA1


"A gap junction alpha-1 protein that is encoded in the genome of rat." [OMA:P08050, PRO:DNx]


organism-sequence



PR:P08050-1

gap junction alpha-1 protein isoform 1 (rat)

rGJA1/iso:1


"A gap junction alpha-1 protein isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000046134

gap junction alpha-1 protein phosphorylated 1 (rat)

rGJA1/Phos:1


"A gap junction alpha-1 protein (rat) that has been phosphorylated at Tyr-265. UniProtKB:P08050, Tyr-265, MOD:00048." [iPTMnet:P08050, PMID:11124251]


organism-gene



PR:P14154

gap junction alpha-1 protein (chicken)

chick-GJA1


"A gap junction alpha-1 protein that is encoded in the genome of chicken." [OMA:P14154, PRO:DNx]


organism-gene



PR:P17302

gap junction alpha-1 protein (human)

hGJA1


"A gap junction alpha-1 protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17302]


organism-sequence



PR:P17302-1

gap junction alpha-1 protein isoform 1 (human)

hGJA1/iso:1


"A gap junction alpha-1 protein isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045690

gap junction alpha-1 protein phosphorylated 1 (human)

hGJA1/Phos:1


"A gap junction alpha-1 protein (human) that has been phosphorylated at Ser-373. UniProtKB:P17302, Ser-373, MOD:00046." [iPTMnet:P17302, PMID:24213533]


organism-modification



PR:000047537

gap junction alpha-1 protein, initiator methionine removed form (human)

hGJA1/InitMet-


"A gap junction alpha-1 protein (human) that has had the initiator methionine removed. UniProtKB:P17302, 2-382." [PRO:DNx, Reactome:R-HSA-158058, Reactome:R-HSA-190544, Reactome:R-HSA-190649, Reactome:R-HSA-190654, Reactome:R-HSA-196173]


organism-modification



PR:000047538

gap junction alpha-1 protein, initiator methionine removed phosphorylated 2 (human)

hGJA1/InitMet-/Phos:2


"A gap junction alpha-1 protein (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at position 265 of the amino acid sequence represented by UniProtKB:P17302. UniProtKB:P17302, 2-382, Tyr-265, MOD:00048." [PRO:DNx, Reactome:R-HSA-191657]


organism-modification



PR:000085898

gap junction alpha-1 protein, initiator methionine removed phosphorylated 1 (human)

hGJA1/InitMet-/Phos:1


"A gap junction alpha-1 protein (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-373 of the amino acid sequence represented by UniProtKB:P17302. UniProtKB:P17302, 2-382, Ser-373, MOD:00046." [PRO:DNx, Reactome:R-HSA-9857671]


organism-gene



PR:P23242

gap junction alpha-1 protein (mouse)

mGJA1


"A gap junction alpha-1 protein that is encoded in the genome of mouse." [OMA:P23242, PRO:DNx]


organism-sequence



PR:P23242-1

gap junction alpha-1 protein isoform 1 (mouse)

mGJA1/iso:1


"A gap junction alpha-1 protein isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000037389

gap junction alpha-1 protein phosphorylated 1 (mouse)

mGJA1/Phos:1


"A gap junction alpha-1 protein (mouse) that has been phosphorylated by pERK1/2 at positions Ser-279 and Ser-282 in UniProtKB:P23242. UniProtKB:P23242, Ser-279/Ser-282, MOD:00046." [PMID:23261543, PRO:HJD]


organism-modification



PR:000037390

gap junction alpha-1 protein unphosphorylated 1 (mouse)

mGJA1/UnPhos:1


"A gap junction alpha-1 protein (mouse) that lacks phosphorylated residues at positions Ser-279 and Ser-282 in UniProtKB:P23242. UniProtKB:P23242, Ser-279/Ser-282, PR:000026291." [PMID:23261543, PRO:HJD]


sequence



PR:000038975

gap junction alpha-1 protein isoform 1

GJA1/iso:1


"A gap junction alpha-1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17302-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P08050-1

gap junction alpha-1 protein isoform 1 (rat)

rGJA1/iso:1


"A gap junction alpha-1 protein isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P17302-1

gap junction alpha-1 protein isoform 1 (human)

hGJA1/iso:1


"A gap junction alpha-1 protein isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P23242-1

gap junction alpha-1 protein isoform 1 (mouse)

mGJA1/iso:1


"A gap junction alpha-1 protein isoform 1 that is encoded in the genome of mouse." [PRO:DNx]