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Protein Ontology report - general transcription factor II-I
PR:000008322 - http://purl.obolibrary.org/obo/PR_000008322
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000008322   
  PRO namegeneral transcription factor II-I 
  Synonyms
PRO-Short-label: EXACT:GTF2I
Gene-based: RELATED:BAP135 | Diws1t | WBSCR6
Other: EXACT:BAP-135 | bruton tyrosine kinase-associated protein 135 | BTK-associated protein 135 | GTFII-I | SPIN | SRF-Phox1-interacting protein | TFII-I | Williams-Beuren syndrome chromosomal region 6 protein
  Definition"A protein that is a translation product of the human GTF2I gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 13                                        
         Modification1                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000008322
general transcription factor II-I
GTF2I
"A protein that is a translation product of the human GTF2I gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P78347
general transcription factor II-I (human)
hGTF2I
"A general transcription factor II-I that is encoded in the genome of human." [PRO:DNx, UniProtKB:P78347]

organism-sequence


PR:P78347-1
general transcription factor II-I isoform h1 (human)
hGTF2I/iso:h1
"A general transcription factor II-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78347-1." [PRO:DNx, UniProtKB:P78347]

organism-sequence


PR:P78347-2
general transcription factor II-I isoform h2 (human)
hGTF2I/iso:h2
"A general transcription factor II-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78347-2." [PRO:DNx, UniProtKB:P78347]

organism-sequence


PR:P78347-3
general transcription factor II-I isoform h3 (human)
hGTF2I/iso:h3
"A general transcription factor II-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78347-3." [PRO:DNx, UniProtKB:P78347]

organism-sequence


PR:P78347-4
general transcription factor II-I isoform h4 (human)
hGTF2I/iso:h4
"A general transcription factor II-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78347-4." [PRO:DNx, UniProtKB:P78347]

organism-sequence


PR:P78347-5
general transcription factor II-I isoform h5 (human)
hGTF2I/iso:h5
"A general transcription factor II-I (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78347-5." [PRO:DNx, UniProtKB:P78347]

organism-modification


PR:000068056
general transcription factor II-I cysteinylated 1 (human)
hGTF2I/Cyst:1
"A general transcription factor II-I (human) that has been cysteinylated on the residue at the position equivalent to Cys-121 of the amino acid sequence represented by UniProtKB:P78347-1. Example: UniProtKB:P78347-1, Cys-121, MOD:00765." [IEDB_epitope:928258, PRO:DNx]

organism-modification


PR:000069555
general transcription factor II-I methylated 1 (human)
hGTF2I/Me:1
"A general transcription factor II-I (human) that has been methylated on the residue at the position equivalent to Cys-215 of the amino acid sequence represented by UniProtKB:P78347-1. Example: UniProtKB:P78347-1, Cys-215, MOD:00660." [IEDB_epitope:1016568, PRO:DNx]

organism-modification


PR:000071248
general transcription factor II-I phosphorylated 1 (human)
hGTF2I/Phos:1
"A general transcription factor II-I (human) that has been phosphorylated on the residue at the position equivalent to Ser-674 of the amino acid sequence represented by UniProtKB:P78347-1. Example: UniProtKB:P78347-1, Ser-674, MOD:00046." [IEDB_epitope:848352, IEDB_epitope:912482, PRO:DNx]

organism-modification


PR:000079890
general transcription factor II-I methylated 2 (human)
hGTF2I/Me:2
"A general transcription factor II-I (human) that has been methylated on the residue at the position equivalent to Cys-121 of the amino acid sequence represented by UniProtKB:P78347-1. Example: UniProtKB:P78347-1, Cys-121, MOD:00660." [IEDB_epitope:1027391, PRO:DNx]

organism-modification


PR:000081737
general transcription factor II-I cysteinylated 2 (human)
hGTF2I/Cyst:2
"A general transcription factor II-I (human) that has been cysteinylated on the residue at the position equivalent to Cys-46 of the amino acid sequence represented by UniProtKB:P78347-1. Example: UniProtKB:P78347-1, Cys-46, MOD:00765." [IEDB_epitope:927993, PRO:DNx]

organism-gene


PR:Q5U2Y1
general transcription factor II-I (rat)
rGTF2I
"A general transcription factor II-I that is encoded in the genome of rat." [OMA:Q5U2Y1, PRO:DNx]

organism-sequence


PR:Q5U2Y1-1
general transcription factor II-I isoform r1 (rat)
rGTF2I/iso:r1
"A general transcription factor II-I (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5U2Y1-1." [PRO:DNx, UniProtKB:Q5U2Y1]

organism-sequence


PR:Q5U2Y1-2
general transcription factor II-I isoform r2 (rat)
rGTF2I/iso:r2
"A general transcription factor II-I (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5U2Y1-2." [PRO:DNx, UniProtKB:Q5U2Y1]

organism-gene


PR:Q9ESZ8
general transcription factor II-I (mouse)
mGTF2I
"A general transcription factor II-I that is encoded in the genome of mouse." [OMA:Q9ESZ8, PRO:DNx]

organism-sequence


PR:Q9ESZ8-1
general transcription factor II-I isoform 1 (mouse)
mGTF2I/iso:1
"A general transcription factor II-I (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ESZ8-1." [PMID:9521869, PRO:HJD]
Yes
organism-sequence


PR:Q9ESZ8-2
general transcription factor II-I isoform 2 (mouse)
mGTF2I/iso:2
"A general transcription factor II-I (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ESZ8-2." [PMID:9521869, PRO:HJD]
Yes
organism-sequence


PR:Q9ESZ8-3
general transcription factor II-I isoform 3 (mouse)
mGTF2I/iso:3
"A general transcription factor II-I (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ESZ8-3." [PMID:9521869, PRO:HJD]

organism-sequence


PR:Q9ESZ8-4
general transcription factor II-I isoform 4 (mouse)
mGTF2I/iso:4
"A general transcription factor II-I (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ESZ8-4." [PMID:9521869, PRO:HJD]
Yes
organism-sequence


PR:Q9ESZ8-5
general transcription factor II-I isoform 5 (mouse)
mGTF2I/iso:5
"A general transcription factor II-I (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ESZ8-5." [PMID:9521869, PRO:HJD]

organism-sequence


PR:Q9ESZ8-6
general transcription factor II-I isoform 6 (mouse)
mGTF2I/iso:6
"A general transcription factor II-I (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ESZ8-6." [PMID:11827466, PRO:HJD]

modification


PR:000020077
general transcription factor II-I, initiator methionine removed form
GTF2I/InitMet-
"A general transcription factor II-I that has had the initiator methionine removed." [PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9ESZ8-1 mGTF2I/iso:1 located_inGO:0005634 nucleus MGI_ref:3044088; PMID:14751286
GO:0042995 cell projection MGI_ref:3044088; PMID:14751286
GO:0043025 neuronal cell body MGI_ref:3044088; PMID:14751286
PR:Q9ESZ8-2 mGTF2I/iso:2 acts_upstream_of_or_withinGO:0014886 transition between slow and fast fiber MGI_ref:5504578; PMID:22899722
located_inGO:0005634 nucleus MGI_ref:3688993; PMID:17052463
PR:Q9ESZ8-4 mGTF2I/iso:4 enablesGO:0051019 mitogen-activated protein kinase binding MGI_ref:3688993; PMID:17052463