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Protein Ontology report - fibroblast growth factor receptor substrate 2
PR:000007670 - http://purl.obolibrary.org/obo/PR_000007670
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000007670   
  PRO namefibroblast growth factor receptor substrate 2 
  Synonyms
PRO-Short-label: EXACT:FRS2
Gene-based: RELATED:Frs2a
Other: EXACT:FGFR substrate 2 | FGFR-signaling adaptor SNT | FRS2-alpha | SNT-1 | suc1-associated neurotrophic factor target 1
  Definition"A protein that is a translation product of the human FRS2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000007670

fibroblast growth factor receptor substrate 2

FRS2


"A protein that is a translation product of the human FRS2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q8C180

fibroblast growth factor receptor substrate 2 (mouse)

mFRS2


"A fibroblast growth factor receptor substrate 2 that is encoded in the genome of mouse." [OMA:Q8C180, PRO:DNx]


organism-sequence



PR:Q8C180-1

fibroblast growth factor receptor substrate 2 isoform 1 (mouse)

mFRS2/iso:1


"A fibroblast growth factor receptor substrate 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]


organism-gene



PR:Q8WU20

fibroblast growth factor receptor substrate 2 (human)

hFRS2


"A fibroblast growth factor receptor substrate 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8WU20]


organism-sequence



PR:Q8WU20-1

fibroblast growth factor receptor substrate 2 isoform 1 (human)

hFRS2/iso:1


"A fibroblast growth factor receptor substrate 2 isoform 1 that is encoded in the genome of human." [PRO:CNx]


organism-modification



PR:000047448

fibroblast growth factor receptor substrate 2, initiator methionine removed form (human)

hFRS2/InitMet-


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed. UniProtKB:Q8WU20, 2-508." [PRO:DNx]


organism-modification



PR:000047449

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 2 (human)

hFRS2/InitMet-/Phos:2


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 132, 135, 138, 376, 452, 455, 458 and 463 of the amino acid sequence represented by UniProtKB:Q8WU20. UniProtKB:Q8WU20, 2-508, Thr-132/Thr-135/Thr-138/Thr-376/Thr-452/Thr-455/Thr-458/Thr-463, MOD:00047." [PRO:DNx, Reactome:R-HSA-1270462]


organism-modification



PR:000061635

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphotyrosine form (human)

hFRS2/InitMet-/PhosTyr+


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed and that includes at least one phosphorylated tyrosine. UniProtKB:Q8WU20, 2-508, MOD:00048." [PRO:DNx, Reactome:R-HSA-162551]


organism-modification



PR:000026214

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 (human)

hFRS2/InitMet-/Phos:1


"A fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 in human. UniProtKB:Q8WU20, 2-508, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:CNx, PRO:DAN]


organism-modification



PR:000061635

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphotyrosine form (human)

hFRS2/InitMet-/PhosTyr+


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed and that includes at least one phosphorylated tyrosine. UniProtKB:Q8WU20, 2-508, MOD:00048." [PRO:DNx, Reactome:R-HSA-162551]


organism-modification



PR:000026214

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 (human)

hFRS2/InitMet-/Phos:1


"A fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 in human. UniProtKB:Q8WU20, 2-508, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:CNx, PRO:DAN]


organism-modification



PR:000085882

fibroblast growth factor receptor substrate 2 phosphorylated 1 (human)

hFRS2/Phos:1


"A fibroblast growth factor receptor substrate 2 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-196, Tyr-306, Tyr-349, Tyr-392, Tyr-436, and Tyr-471 of the amino acid sequence represented by UniProtKB:Q8WU20. UniProtKB:Q8WU20, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:DNx, Reactome:R-HSA-170959]


sequence



PR:000026207

fibroblast growth factor receptor substrate 2 isoform 1

FRS2/iso:1


"A fibroblast growth factor receptor substrate 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WU20-1 or a 1:1 ortholog thereof." [PRO:CNx]


organism-sequence



PR:Q8C180-1

fibroblast growth factor receptor substrate 2 isoform 1 (mouse)

mFRS2/iso:1


"A fibroblast growth factor receptor substrate 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]


organism-sequence



PR:Q8WU20-1

fibroblast growth factor receptor substrate 2 isoform 1 (human)

hFRS2/iso:1


"A fibroblast growth factor receptor substrate 2 isoform 1 that is encoded in the genome of human." [PRO:CNx]


modification



PR:000026579

fibroblast growth factor receptor substrate 2 isoform 1, initiator methionine removed form

FRS2/iso:1/InitMet-


"A fibroblast growth factor receptor substrate 2 isoform 1 that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000019931

fibroblast growth factor receptor substrate 2, initiator methionine removed form

FRS2/InitMet-


"A fibroblast growth factor receptor substrate 2 that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000026209

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1

FRS2/InitMet-/Phos:1


"A fibroblast growth factor receptor substrate 2, initiator methionine removed form that has been phosphorylated by activated TrkA. FRS2 is an adapter protein that links NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Example: UniProtKB:Q8WU20-1, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-170959, Reactome:R-HSA-190062]


organism-modification



PR:000026214

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 (human)

hFRS2/InitMet-/Phos:1


"A fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 in human. UniProtKB:Q8WU20, 2-508, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:CNx, PRO:DAN]


modification



PR:000026579

fibroblast growth factor receptor substrate 2 isoform 1, initiator methionine removed form

FRS2/iso:1/InitMet-


"A fibroblast growth factor receptor substrate 2 isoform 1 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000047448

fibroblast growth factor receptor substrate 2, initiator methionine removed form (human)

hFRS2/InitMet-


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed. UniProtKB:Q8WU20, 2-508." [PRO:DNx]


organism-modification



PR:000047449

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 2 (human)

hFRS2/InitMet-/Phos:2


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 132, 135, 138, 376, 452, 455, 458 and 463 of the amino acid sequence represented by UniProtKB:Q8WU20. UniProtKB:Q8WU20, 2-508, Thr-132/Thr-135/Thr-138/Thr-376/Thr-452/Thr-455/Thr-458/Thr-463, MOD:00047." [PRO:DNx, Reactome:R-HSA-1270462]


organism-modification



PR:000061635

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphotyrosine form (human)

hFRS2/InitMet-/PhosTyr+


"A fibroblast growth factor receptor substrate 2 (human) that has had the initiator methionine removed and that includes at least one phosphorylated tyrosine. UniProtKB:Q8WU20, 2-508, MOD:00048." [PRO:DNx, Reactome:R-HSA-162551]


organism-modification



PR:000026214

fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 (human)

hFRS2/InitMet-/Phos:1


"A fibroblast growth factor receptor substrate 2, initiator methionine removed phosphorylated 1 in human. UniProtKB:Q8WU20, 2-508, Tyr-196/Tyr-306/Tyr-349/Tyr-392/Tyr-436/Tyr-471, MOD:00048." [PRO:CNx, PRO:DAN]