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Protein Ontology report - ficolin-1
PR:000007437 - http://purl.obolibrary.org/obo/PR_000007437
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000007437   
  PRO nameficolin-1 
  Synonyms
PRO-Short-label: EXACT:FCN1
Gene-based: RELATED:Fcna | FCNM
Other: EXACT:collagen/fibrinogen domain-containing protein 1 | ficolin-A | ficolin-alpha | M-ficolin
  Definition"A protein that is a translation product of the human FCN1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000007437

ficolin-1

FCN1


"A protein that is a translation product of the human FCN1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O00602

ficolin-1 (human)

hFCN1


"A ficolin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00602]


organism-modification



PR:000047390

ficolin-1, signal peptide removed form (human)

hFCN1/SigPep-


"A ficolin-1 (human) that has had the signal peptide removed. UniProtKB:O00602, 30-326." [PRO:DNx, Reactome:R-HSA-2530451]


organism-gene



PR:O70165

ficolin-1 (mouse)

mFCN1


"A ficolin-1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:O70165-1

ficolin-1 isoform 1 (mouse)

mFCN1/iso:1


"A ficolin-1 isoform 1 that is encoded in the genome of mouse." [PMID:9535745, PRO:HJD]

Yes

organism-sequence



PR:Q2WFW2

ficolin-1 isoform 2 (mouse)

mFCN1/iso:2


"A ficolin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2WFW2. This isoform has shortened G-x-y repeats interrupted by a longer gap sequence, including five new amino acids, and a fibrinogen-like domain identical to ficolin A isoform 1." [PMID:16328467, PRO:HJD]


organism-gene



PR:Q9WTS8

ficolin-1 (rat)

rFCN1


"A ficolin-1 that is encoded in the genome of rat." [PRO:DAN]


organism-sequence



PR:Q9WTS8-1

ficolin-1 isoform 1 (rat)

rFCN1/iso:1


"A ficolin-1 isoform 1 that is encoded in the genome of rat." [PMID:17579066, PRO:CNA]


sequence



PR:000037127

ficolin-1 isoform 1

FCN1/iso:1


"A ficolin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70165-1 or a 1:1 ortholog thereof." [PMID:9535745, PRO:HJD]


organism-sequence



PR:O70165-1

ficolin-1 isoform 1 (mouse)

mFCN1/iso:1


"A ficolin-1 isoform 1 that is encoded in the genome of mouse." [PMID:9535745, PRO:HJD]

Yes

organism-sequence



PR:Q9WTS8-1

ficolin-1 isoform 1 (rat)

rFCN1/iso:1


"A ficolin-1 isoform 1 that is encoded in the genome of rat." [PMID:17579066, PRO:CNA]


modification



PR:000019860

ficolin-1, signal peptide removed form

FCN1/SigPep-


"A ficolin-1 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000047390

ficolin-1, signal peptide removed form (human)

hFCN1/SigPep-


"A ficolin-1 (human) that has had the signal peptide removed. UniProtKB:O00602, 30-326." [PRO:DNx, Reactome:R-HSA-2530451]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O70165-1 mFCN1/iso:1 acts_upstream_of_or_withinGO:0001867 complement activation, lectin pathway MGI_ref:5473786; PMID:16328467
enablesGO:0005515 protein binding with PR:Q91WP0-1|PR:Q91WP0-2 MGI_ref:5473786; PMID:16328467
GO:0097367 carbohydrate derivative binding MGI_ref:5473786; PMID:16328467