back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - histone-lysine N-methyltransferase EZH2
PR:000007278 - http://purl.obolibrary.org/obo/PR_000007278
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000007278   
  PRO namehistone-lysine N-methyltransferase EZH2 
  Synonyms
PRO-Short-label: EXACT:EZH2
Gene-based: RELATED:Enx1h | KMT6
Other: EXACT:enhancer of zeste homolog 2 | ENX-1 | lysine N-methyltransferase 6
  Definition"A protein that is a translation product of the human EZH2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:2654
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000007278
histone-lysine N-methyltransferase EZH2
EZH2
"A protein that is a translation product of the human EZH2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P42124
histone-lysine N-methyltransferase E(z) (fruit fly)
fly-EZH2
"A histone-lysine N-methyltransferase EZH2 that is encoded in the genome of fruit fly." [PRO:DNx]

organism-gene


PR:Q08BS4
histone-lysine N-methyltransferase EZH2 (zebrafish)
z-EZH2
"A histone-lysine N-methyltransferase EZH2 that is encoded in the genome of zebrafish." [PRO:DNx]

organism-gene


PR:Q15910
histone-lysine N-methyltransferase EZH2 (human)
hEZH2
"A histone-lysine N-methyltransferase EZH2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15910]

organism-sequence


PR:Q15910-1
histone-lysine N-methyltransferase EZH2 isoform 1 (human)
hEZH2/iso:1
"A histone-lysine N-methyltransferase EZH2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q15910-2
histone-lysine N-methyltransferase EZH2 isoform h2 (human)
hEZH2/iso:h2
"A histone-lysine N-methyltransferase EZH2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15910-2." [PRO:DNx, UniProtKB:Q15910]

organism-sequence


PR:Q15910-3
histone-lysine N-methyltransferase EZH2 isoform h3 (human)
hEZH2/iso:h3
"A histone-lysine N-methyltransferase EZH2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15910-3." [PRO:DNx, UniProtKB:Q15910]

organism-sequence


PR:Q15910-4
histone-lysine N-methyltransferase EZH2 isoform h4 (human)
hEZH2/iso:h4
"A histone-lysine N-methyltransferase EZH2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15910-4." [PRO:DNx, UniProtKB:Q15910]

organism-sequence


PR:Q15910-5
histone-lysine N-methyltransferase EZH2 isoform h5 (human)
hEZH2/iso:h5
"A histone-lysine N-methyltransferase EZH2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15910-5." [PRO:DNx, UniProtKB:Q15910]

organism-modification


PR:000045949
histone-lysine N-methyltransferase EZH2 phosphorylated 1 (human)
hEZH2/Phos:1
"A histone-lysine N-methyltransferase EZH2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-416 of the amino acid sequence represented by UniProtKB:Q15910-1. Example: UniProtKB:Q15910-1, Thr-416, MOD:00047." [iPTMnet:Q15910, PMID:23241245, PMID:26279746]

organism-modification


PR:000068062
histone-lysine N-methyltransferase EZH2 methylated 1 (human)
hEZH2/Me:1
"A histone-lysine N-methyltransferase EZH2 (human) that has been methylated on the residue at the position equivalent to Cys-463 of the amino acid sequence represented by UniProtKB:Q15910-1. Example: UniProtKB:Q15910-1, Cys-463, MOD:00660." [IEDB_epitope:1042903, PRO:DNx]

organism-modification


PR:000070279
histone-lysine N-methyltransferase EZH2 methylated 2 (human)
hEZH2/Me:2
"A histone-lysine N-methyltransferase EZH2 (human) that has been methylated on the residue at the position equivalent to Cys-695 of the amino acid sequence represented by UniProtKB:Q15910-1. Example: UniProtKB:Q15910-1, Cys-695, MOD:00660." [IEDB_epitope:1052656, PRO:DNx]

organism-modification


PR:000072052
histone-lysine N-methyltransferase EZH2 cysteinylated 1 (human)
hEZH2/Cyst:1
"A histone-lysine N-methyltransferase EZH2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-452 of the amino acid sequence represented by UniProtKB:Q15910-1. Example: UniProtKB:Q15910-1, Cys-452, MOD:00765." [IEDB_epitope:1594714, PRO:DNx]

organism-modification


PR:000078272
histone-lysine N-methyltransferase EZH2 methylated 3 (human)
hEZH2/Me:3
"A histone-lysine N-methyltransferase EZH2 (human) that has been methylated on the residue at the position equivalent to Cys-452 of the amino acid sequence represented by UniProtKB:Q15910-1. Example: UniProtKB:Q15910-1, Cys-452, MOD:00660." [IEDB_epitope:1005800, IEDB_epitope:1056358, PRO:DNx]

organism-gene


PR:Q61188
histone-lysine N-methyltransferase EZH2 (mouse)
mEZH2
"A histone-lysine N-methyltransferase EZH2 that is encoded in the genome of mouse." [OMA:Q61188, PRO:DNx]

organism-sequence


PR:Q61188-1
histone-lysine N-methyltransferase EZH2 isoform ENX-1A (mouse)
mEZH2/iso:ENX-1A
"A histone-lysine N-methyltransferase EZH2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:Q61188-2
histone-lysine N-methyltransferase EZH2 isoform mENX-1B (mouse)
mEZH2/iso:mENX-1B
"A histone-lysine N-methyltransferase EZH2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61188-2." [PRO:DNx, UniProtKB:Q61188]

organism-sequence


PR:Q6AXH7
histone-lysine N-methyltransferase EZH2 isoform Q6AXH7 (mouse)
mEZH2/iso:Q6AXH7
"A histone-lysine N-methyltransferase EZH2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6AXH7." [PMID:23624931, PRO:DNx, PRO:HJD, UniProtKB:Q6AXH7]

organism-modification


PR:000076230
histone-lysine N-methyltransferase EZH2 cysteinylated 1 (mouse)
mEZH2/Cyst:1
"A histone-lysine N-methyltransferase EZH2 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-642 of the amino acid sequence represented by UniProtKB:Q61188-1. Example: UniProtKB:Q61188-1, Cys-642, MOD:00765." [IEDB_epitope:2107088, PRO:DNx]

sequence


PR:000040685
histone-lysine N-methyltransferase EZH2 isoform 1
EZH2/iso:1
"A histone-lysine N-methyltransferase EZH2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15910-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q15910-1
histone-lysine N-methyltransferase EZH2 isoform 1 (human)
hEZH2/iso:1
"A histone-lysine N-methyltransferase EZH2 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q61188-1
histone-lysine N-methyltransferase EZH2 isoform ENX-1A (mouse)
mEZH2/iso:ENX-1A
"A histone-lysine N-methyltransferase EZH2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]