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Protein Ontology report - serine/threonine-protein kinase/endoribonuclease IRE1
PR:000007185 - http://purl.obolibrary.org/obo/PR_000007185
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000007185   
  PRO nameserine/threonine-protein kinase/endoribonuclease IRE1 
  Synonyms
PRO-Short-label: EXACT:ERN1
Gene-based: RELATED:IRE1
Other: EXACT:endoplasmic reticulum-to-nucleus signaling 1 | inositol-requiring protein 1 | ire1-alpha | IRE1a | IRE1p
  Definition"A protein that is a translation product of the human ERN1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2020
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000007185
serine/threonine-protein kinase/endoribonuclease IRE1
ERN1
"A protein that is a translation product of the human ERN1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O75460
serine/threonine-protein kinase/endoribonuclease IRE1 (human)
hERN1
"A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75460]

organism-sequence


PR:O75460-1
serine/threonine-protein kinase/endoribonuclease IRE1 isoform h1 (human)
hERN1/iso:h1
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75460-1." [PRO:DNx, UniProtKB:O75460]

organism-sequence


PR:O75460-2
serine/threonine-protein kinase/endoribonuclease IRE1 isoform h2 (human)
hERN1/iso:h2
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75460-2." [PRO:DNx, UniProtKB:O75460]

organism-modification


PR:000063166
serine/threonine-protein kinase/endoribonuclease IRE1, signal peptide removed form (human)
hERN1/SigPep-
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has had the signal peptide removed. Example: UniProtKB:O75460-1, 19-977." [PRO:DNx, Reactome:R-HSA-381076]

organism-modification


PR:000063683
serine/threonine-protein kinase/endoribonuclease IRE1, signal peptide removed phosphorylated 1 (human)
hERN1/SigPep-/Phos:1
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Ser-724 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, 19-977, Ser-724, MOD:00046." [PRO:DNx, Reactome:R-HSA-381029]

organism-modification


PR:000073719
serine/threonine-protein kinase/endoribonuclease IRE1 cysteinylated 1 (human)
hERN1/Cyst:1
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-630 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, Cys-630, MOD:00765." [IEDB_epitope:924964, PRO:DNx]

organism-modification


PR:000078305
serine/threonine-protein kinase/endoribonuclease IRE1 deaminated 1 (human)
hERN1/Deam:1
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has been deaminated on the residue at the position equivalent to Gln-475 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, Gln-475, MOD:00685." [IEDB_epitope:1584799, PRO:DNx]

organism-modification


PR:000078501
serine/threonine-protein kinase/endoribonuclease IRE1 deaminated 2 (human)
hERN1/Deam:2
"A serine/threonine-protein kinase/endoribonuclease IRE1 (human) that has been deaminated on the residue at the position equivalent to Gln-473 of the amino acid sequence represented by UniProtKB:O75460-1. Example: UniProtKB:O75460-1, Gln-473, MOD:00685." [IEDB_epitope:1584798, PRO:DNx]

organism-gene


PR:Q9EQY0
serine/threonine-protein kinase/endoribonuclease IRE1 (mouse)
mERN1
"A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of mouse." [OMA:Q9EQY0, PRO:DNx]

organism-sequence


PR:Q9EQY0-1
serine/threonine-protein kinase/endoribonuclease IRE1 isoform m1 (mouse)
mERN1/iso:m1
"A serine/threonine-protein kinase/endoribonuclease IRE1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQY0-1." [PRO:DNx, UniProtKB:Q9EQY0]

organism-sequence


PR:Q9EQY0-2
serine/threonine-protein kinase/endoribonuclease IRE1 isoform m2 (mouse)
mERN1/iso:m2
"A serine/threonine-protein kinase/endoribonuclease IRE1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQY0-2." [PRO:DNx, UniProtKB:Q9EQY0]