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Protein Ontology report - eIF-2-alpha kinase GCN2
PR:000006961 - http://purl.obolibrary.org/obo/PR_000006961
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000006961   
  PRO nameeIF-2-alpha kinase GCN2 
  Synonyms
PRO-Short-label: EXACT:EIF2AK4
Gene-based: RELATED:GCN2 | KIAA1338
Other: EXACT:eukaryotic translation initiation factor 2-alpha kinase 4 | GCN2-like protein
  Definition"A protein that is a translation product of the human EIF2AK4 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence0                                                  Organism-Sequence 11                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2018
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000006961

eIF-2-alpha kinase GCN2

EIF2AK4


"A protein that is a translation product of the human EIF2AK4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:000050561

eIF-2-alpha kinase GCN2 (Schizosaccharomyces pombe)

Spom-EIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of Schizosaccharomyces pombe." [OMA:Q9HGN1, PRO:DNx]


organism-gene



PR:Q9HGN1

eIF-2-alpha kinase GCN2 (Schizosaccharomyces pombe 972h-)

Spom972h-EIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9HGN1, PRO:DNx]


organism-gene



PR:D0Z5N4

eukaryotic translation initiation factor 2-alpha kinase gcn-2 (worm)

EIF2AK4 (worm)


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of worm." [OMA:D0Z5N4, PRO:DNx]


organism-sequence



PR:D0Z5N4-1

eukaryotic translation initiation factor 2-alpha kinase gcn-2 isoform b (worm)

EIF2AK4/iso:b (worm)


"A eukaryotic translation initiation factor 2-alpha kinase gcn-2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:D0Z5N4-1." [PRO:DNx, UniProtKB:D0Z5N4]


organism-sequence



PR:D0Z5N4-2

eukaryotic translation initiation factor 2-alpha kinase gcn-2 isoform a (worm)

EIF2AK4/iso:a (worm)


"A eukaryotic translation initiation factor 2-alpha kinase gcn-2 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:D0Z5N4-2." [PRO:DNx, UniProtKB:D0Z5N4]


organism-gene



PR:D4A7V9

eIF-2-alpha kinase GCN2 (rat)

rEIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of rat." [OMA:D4A7V9, PRO:DNx]


organism-gene



PR:P15442

eIF-2-alpha kinase GCN2 (yeast)

yEIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of yeast." [OMA:P15442, PRO:DNx]


organism-modification



PR:000046144

eIF-2-alpha kinase GCN2 phosphorylated 1 (yeast)

yEIF2AK4/Phos:1


"An eIF-2-alpha kinase GCN2 (yeast) that has been phosphorylated at Ser-577. UniProtKB:P15442, Ser-577, MOD:00046." [iPTMnet:P15442, PMID:12070158]


organism-gene



PR:Q9HGN1

eIF-2-alpha kinase GCN2 (Schizosaccharomyces pombe 972h-)

Spom972h-EIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9HGN1, PRO:DNx]


organism-gene



PR:Q9P2K8

eIF-2-alpha kinase GCN2 (human)

hEIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9P2K8]


organism-sequence



PR:Q9P2K8-1

eIF-2-alpha kinase GCN2 isoform h1 (human)

hEIF2AK4/iso:h1


"An eIF-2-alpha kinase GCN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2K8-1." [PRO:DNx, UniProtKB:Q9P2K8]


organism-sequence



PR:Q9P2K8-2

eIF-2-alpha kinase GCN2 isoform h2 (human)

hEIF2AK4/iso:h2


"An eIF-2-alpha kinase GCN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2K8-2." [PRO:DNx, UniProtKB:Q9P2K8]


organism-sequence



PR:Q9P2K8-3

eIF-2-alpha kinase GCN2 isoform h3 (human)

hEIF2AK4/iso:h3


"An eIF-2-alpha kinase GCN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2K8-3." [PRO:DNx, UniProtKB:Q9P2K8]


organism-modification



PR:000063194

eIF-2-alpha kinase GCN2 phosphorylated 1 (human)

hEIF2AK4/Phos:1


"An eIF-2-alpha kinase GCN2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-899 of the amino acid sequence represented by UniProtKB:Q9P2K8-1. Example: UniProtKB:Q9P2K8-1, Thr-899, MOD:00047." [PRO:DNx, Reactome:R-HSA-9633781]


organism-gene



PR:Q9QZ05

eIF-2-alpha kinase GCN2 (mouse)

mEIF2AK4


"An eIF-2-alpha kinase GCN2 that is encoded in the genome of mouse." [OMA:Q9QZ05, PRO:DNx]


organism-sequence



PR:Q9QZ05-1

eIF-2-alpha kinase GCN2 isoform 1 (mouse)

mEIF2AK4/iso:1


"An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-1." [PRO:DNx, UniProtKB:Q9QZ05]


organism-modification



PR:000044810

eIF-2-alpha kinase GCN2 isoform 1 phosphorylated form (mouse)

mEIF2AK4/iso:1/PhosRes+


"An eIF-2-alpha kinase GCN2 isoform 1 (mouse) that includes at least one phosphorylated residue. UniProtKB:Q9QZ05-1, MOD:00696." [PMID:18996085, PRO:KRC]

Yes

organism-sequence



PR:Q9QZ05-2

eIF-2-alpha kinase GCN2 isoform m2 (mouse)

mEIF2AK4/iso:m2


"An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-2." [PRO:DNx, UniProtKB:Q9QZ05]


organism-sequence



PR:Q9QZ05-3

eIF-2-alpha kinase GCN2 isoform m3 (mouse)

mEIF2AK4/iso:m3


"An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-3." [PRO:DNx, UniProtKB:Q9QZ05]


organism-sequence



PR:Q9QZ05-4

eIF-2-alpha kinase GCN2 isoform m4 (mouse)

mEIF2AK4/iso:m4


"An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-4." [PRO:DNx, UniProtKB:Q9QZ05]


organism-sequence



PR:Q9QZ05-5

eIF-2-alpha kinase GCN2 isoform m5 (mouse)

mEIF2AK4/iso:m5


"An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-5." [PRO:DNx, UniProtKB:Q9QZ05]


organism-sequence



PR:Q9QZ05-6

eIF-2-alpha kinase GCN2 isoform m6 (mouse)

mEIF2AK4/iso:m6


"An eIF-2-alpha kinase GCN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QZ05-6." [PRO:DNx, UniProtKB:Q9QZ05]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044810 mEIF2AK4/iso:1/PhosRes+
UniProtKB:Q9QZ05-1, MOD:00696
located_inGO:0005622 intracellular anatomical structure MGI_ref:3823138; PMID:18996085