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Protein Ontology report - dihydropyrimidine dehydrogenase [NADP(+)]
PR:000006678 - http://purl.obolibrary.org/obo/PR_000006678
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000006678   
  PRO namedihydropyrimidine dehydrogenase [NADP(+)] 
  Synonyms
PRO-Short-label: EXACT:DPYD
Other: EXACT:DHPDHase
  Definition"A protein that is a translation product of the human DPYD gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000006678

dihydropyrimidine dehydrogenase [NADP(+)]

DPYD


"A protein that is a translation product of the human DPYD gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O89000

dihydropyrimidine dehydrogenase [NADP(+)] (rat)

rDPYD


"A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of rat." [OMA:O89000, PRO:DNx]


organism-sequence



PR:O89000-1

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (rat)

rDPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q12882

dihydropyrimidine dehydrogenase [NADP(+)] (human)

hDPYD


"A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q12882]


organism-sequence



PR:Q12882-1

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (human)

hDPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q12882-2

dihydropyrimidine dehydrogenase [NADP(+)] isoform h2 (human)

hDPYD/iso:h2


"A dihydropyrimidine dehydrogenase [NADP(+)] (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12882-2." [PRO:DNx, UniProtKB:Q12882]


organism-modification



PR:000076844

dihydropyrimidine dehydrogenase [NADP(+)] cysteinylated 1 (human)

hDPYD/Cyst:1


"A dihydropyrimidine dehydrogenase [NADP(+)] (human) that has been cysteinylated on the residue at the position equivalent to Cys-695 of the amino acid sequence represented by UniProtKB:Q12882-1. Example: UniProtKB:Q12882-1, Cys-695, MOD:00765." [IEDB_epitope:877303, PRO:DNx]


organism-modification



PR:000078852

dihydropyrimidine dehydrogenase [NADP(+)], mature form (human)

hDPYD/mature


"A dihydropyrimidine dehydrogenase [NADP(+)] (human) that has had the propeptide removed. Example: UniProtKB:Q12882-1, 4-1025." [PRO:DNx, Reactome:R-HSA-73525]


organism-modification



PR:000085110

dihydropyrimidine dehydrogenase [NADP(+)] phosphorylated 1 (human)

hDPYD/Phos:1


"A dihydropyrimidine dehydrogenase [NADP(+)] (human) that has been phosphorylated on the residue at the position equivalent to Thr-760 of the amino acid sequence represented by UniProtKB:Q12882-1. Example: UniProtKB:Q12882-1, Thr-760, MOD:00047." [IEDB_epitope:1360109, PRO:DNx]


organism-gene



PR:Q18164

dihydropyrimidine dehydrogenase [NADP(+)] (worm)

DPYD (worm)


"A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of worm." [OMA:Q18164, PRO:DNx]


organism-gene



PR:Q55FT1

dihydropyrimidine dehydrogenase [NADP(+)] (Dictyostelium discoideum)

Dicty-DPYD


"A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FT1, PRO:DNx]


organism-gene



PR:Q8CHR6

dihydropyrimidine dehydrogenase [NADP(+)] (mouse)

mDPYD


"A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of mouse." [OMA:Q8CHR6, PRO:DNx]


organism-sequence



PR:Q8CHR6-1

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (mouse)

mDPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000040372

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1

DPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12882-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O89000-1

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (rat)

rDPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q12882-1

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (human)

hDPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q8CHR6-1

dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 (mouse)

mDPYD/iso:1


"A dihydropyrimidine dehydrogenase [NADP(+)] isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000019705

dihydropyrimidine dehydrogenase [NADP(+)] proteolytic cleavage product

DPYD/ClvPrd


"A dihydropyrimidine dehydrogenase [NADP(+)] that has been processed by proteolytic cleavage." [PRO:DNx]