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Protein Ontology report - death-associated protein kinase 1
PR:000006276 - http://purl.obolibrary.org/obo/PR_000006276
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000006276   
  PRO namedeath-associated protein kinase 1 
  Synonyms
PRO-Short-label: EXACT:DAPK1
Gene-based: RELATED:DAPK
Other: EXACT:DAP kinase 1
  Definition"A death-associated protein kinase that is a translation product of the human DAPK1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000029896 death-associated protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2002
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000006276
death-associated protein kinase 1
DAPK1
"A death-associated protein kinase that is a translation product of the human DAPK1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:O44997
death-associated protein kinase dapk-1 (worm)
DAPK1 (worm)
"A death-associated protein kinase 1 that is encoded in the genome of worm." [PRO:DNx]

organism-gene


PR:P53355
death-associated protein kinase 1 (human)
hDAPK1
"A death-associated protein kinase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P53355]

organism-sequence


PR:P53355-1
death-associated protein kinase 1 isoform 1 (human)
hDAPK1/iso:1
"A death-associated protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:P53355-2
death-associated protein kinase 1 isoform h2 (human)
hDAPK1/iso:h2
"A death-associated protein kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53355-2." [PRO:DNx, UniProtKB:P53355]

organism-sequence


PR:P53355-3
death-associated protein kinase 1 isoform h3 (human)
hDAPK1/iso:h3
"A death-associated protein kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53355-3." [PRO:DNx, UniProtKB:P53355]

organism-sequence


PR:P53355-4
death-associated protein kinase 1 isoform h4 (human)
hDAPK1/iso:h4
"A death-associated protein kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53355-4." [PRO:DNx, UniProtKB:P53355]

organism-modification


PR:000045827
death-associated protein kinase 1 phosphorylated 1 (human)
hDAPK1/Phos:1
"A death-associated protein kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-289 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Ser-289, MOD:00046." [iPTMnet:P53355, PMID:16213824]

organism-modification


PR:000066395
death-associated protein kinase 1 deaminated 1 (human)
hDAPK1/Deam:1
"A death-associated protein kinase 1 (human) that has been deaminated on the residue at the position equivalent to Asn-125 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Asn-125, MOD:00684." [IEDB_epitope:1316644, PRO:DNx]

organism-modification


PR:000068193
death-associated protein kinase 1 methylated 1 (human)
hDAPK1/Me:1
"A death-associated protein kinase 1 (human) that has been methylated on the residue at the position equivalent to Cys-484 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Cys-484, MOD:00660." [IEDB_epitope:1007496, PRO:DNx]

organism-modification


PR:000069422
death-associated protein kinase 1 phosphorylated 2 (human)
hDAPK1/Phos:2
"A death-associated protein kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1429 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Ser-1429, MOD:00046." [IEDB_epitope:990639, PRO:DNx]

organism-modification


PR:000074965
death-associated protein kinase 1 deaminated 2 (human)
hDAPK1/Deam:2
"A death-associated protein kinase 1 (human) that has been deaminated on the residue at the position equivalent to Asn-747 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Asn-747, MOD:00684." [IEDB_epitope:1997727, PRO:DNx]

organism-modification


PR:000079937
death-associated protein kinase 1 methylated 2 (human)
hDAPK1/Me:2
"A death-associated protein kinase 1 (human) that has been methylated on the residue at the position equivalent to Cys-529 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Cys-529, MOD:00660." [IEDB_epitope:1017182, PRO:DNx]

organism-modification


PR:000080074
death-associated protein kinase 1 phosphorylated 3 (human)
hDAPK1/Phos:3
"A death-associated protein kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-87 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Thr-87, MOD:00047." [IEDB_epitope:2146441, PRO:DNx]

organism-modification


PR:000083050
death-associated protein kinase 1 cysteinylated 1 (human)
hDAPK1/Cyst:1
"A death-associated protein kinase 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-753 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Cys-753, MOD:00765." [IEDB_epitope:1035756, PRO:DNx]

organism-modification


PR:000083534
death-associated protein kinase 1 deaminated 3 (human)
hDAPK1/Deam:3
"A death-associated protein kinase 1 (human) that has been deaminated on the residue at the position equivalent to Gln-38 of the amino acid sequence represented by UniProtKB:P53355-1. Example: UniProtKB:P53355-1, Gln-38, MOD:00685." [IEDB_epitope:929868, PRO:DNx]

organism-gene


PR:Q80YE7
death-associated protein kinase 1 (mouse)
mDAPK1
"A death-associated protein kinase 1 that is encoded in the genome of mouse." [OMA:Q80YE7, PRO:DNx]

organism-sequence


PR:Q80YE7-1
death-associated protein kinase 1 isoform 1 (mouse)
mDAPK1/iso:1
"A death-associated protein kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80YE7-1." [PRO:DNx, UniProtKB:Q80YE7]
Yes
organism-sequence


PR:Q80YE7-2
death-associated protein kinase 1 isoform 2 (mouse)
mDAPK1/iso:2
"A death-associated protein kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

sequence


PR:000039728
death-associated protein kinase 1 isoform 1
DAPK1/iso:1
"A death-associated protein kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53355-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P53355-1
death-associated protein kinase 1 isoform 1 (human)
hDAPK1/iso:1
"A death-associated protein kinase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]

organism-sequence


PR:Q80YE7-2
death-associated protein kinase 1 isoform 2 (mouse)
mDAPK1/iso:2
"A death-associated protein kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q80YE7-1 mDAPK1/iso:1 acts_upstream_of_or_withinGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors MGI_ref:2152512; PMID:11485996