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Protein Ontology report - corticotropin-releasing factor receptor 2
PR:000005870 - http://purl.obolibrary.org/obo/PR_000005870
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005870   
  PRO namecorticotropin-releasing factor receptor 2 
  Synonyms
PRO-Short-label: EXACT:CRHR2
Gene-based: RELATED:CRF2R | CRH2R
Other: EXACT:corticotropin-releasing hormone receptor 2 | CRF-R-2 | CRF-R2 | CRF-RB | CRFR-2 | CRH-R-2 | CRH-R2
  Definition"A corticotropin-releasing factor receptor that is a translation product of the human CRHR2 gene or a 1:1 ortholog thereof." [PRO:DAN] 
  PRO Categorygene 
  ParentPR:000044630 corticotropin-releasing factor receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence4                                                  Organism-Sequence 12                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:213
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000005870
corticotropin-releasing factor receptor 2
CRHR2
"A corticotropin-releasing factor receptor that is a translation product of the human CRHR2 gene or a 1:1 ortholog thereof." [PRO:DAN]

organism-gene


PR:P47866
corticotropin-releasing factor receptor 2 (rat)
rCRHR2
"A corticotropin-releasing factor receptor 2 that is encoded in the genome of rat." [OMA:P47866, PRO:DNx]

organism-sequence


PR:P47866-1
corticotropin-releasing factor receptor 2 isoform rCRF2-alpha (rat)
rCRHR2/iso:rCRF2-alpha
"A corticotropin-releasing factor receptor 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47866-1." [PRO:DNx, UniProtKB:P47866]

organism-sequence


PR:P47866-2
corticotropin-releasing factor receptor 2 isoform rCRF2-beta (rat)
rCRHR2/iso:rCRF2-beta
"A corticotropin-releasing factor receptor 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47866-2." [PRO:DNx, UniProtKB:P47866]

organism-gene


PR:Q13324
corticotropin-releasing factor receptor 2 (human)
hCRHR2
"A corticotropin-releasing factor receptor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13324]

organism-sequence


PR:Q13324-1
corticotropin-releasing factor receptor 2 isoform alpha (human)
hCRHR2/iso:alpha
"A corticotropin-releasing factor receptor 2 isoform alpha that is encoded in the genome of human." [PMID:8536644, PRO:CNA]

organism-sequence


PR:Q13324-2
corticotropin-releasing factor receptor 2 isoform beta (human)
hCRHR2/iso:beta
"A corticotropin-releasing factor receptor 2 isoform beta that is encoded in the genome of human." [PMID:9199241, PRO:CNA]

organism-sequence


PR:Q13324-3
corticotropin-releasing factor receptor 2 isoform gamma (human)
hCRHR2/iso:gamma
"A corticotropin-releasing factor receptor 2 isoform gamma that is encoded in the genome of human." [PMID:9717834, PRO:CNA]

organism-sequence


PR:Q13324-4
corticotropin-releasing factor receptor 2 isoform D (human)
hCRHR2/iso:D
"A corticotropin-releasing factor receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-4." [PRO:DNx, UniProtKB:Q13324]

organism-sequence


PR:Q13324-5
corticotropin-releasing factor receptor 2 isoform E (human)
hCRHR2/iso:E
"A corticotropin-releasing factor receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-5." [PRO:DNx, UniProtKB:Q13324]

organism-sequence


PR:Q13324-6
corticotropin-releasing factor receptor 2 isoform F (human)
hCRHR2/iso:F
"A corticotropin-releasing factor receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-6." [PRO:DNx, UniProtKB:Q13324]

organism-sequence


PR:Q13324-7
corticotropin-releasing factor receptor 2 isoform desQ (human)
hCRHR2/iso:desQ
"A corticotropin-releasing factor receptor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-7." [PRO:DNx, UniProtKB:Q13324]

organism-gene


PR:Q60748
corticotropin-releasing factor receptor 2 (mouse)
mCRHR2
"A corticotropin-releasing factor receptor 2 that is encoded in the genome of mouse." [OMA:Q60748, PRO:DAN]

organism-sequence


PR:C0K3M3
corticotropin-releasing factor receptor 2 isoform iv-beta (mouse)
mCRHR2/iso:iv-beta
"A corticotropin-releasing factor receptor 2 isoform iv-beta that is encoded in the genome of mouse." [PMID:7708757, PRO:HJD]
Yes
organism-sequence


PR:Q60748-1
corticotropin-releasing factor receptor 2 isoform mCRF2-alpha (mouse)
mCRHR2/iso:mCRF2-alpha
"A corticotropin-releasing factor receptor 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60748-1." [PRO:DNx, UniProtKB:Q60748]

organism-sequence


PR:Q60748-2
corticotropin-releasing factor receptor 2 isoform beta (mouse)
mCRHR2/iso:beta
"A corticotropin-releasing factor receptor 2 isoform beta that is encoded in the genome of mouse." [PMID:7708757, PRO:HJD]
Yes
sequence


PR:000026079
corticotropin-releasing factor receptor 2 isoform alpha
CRHR2/iso:alpha
"A corticotropin-releasing factor receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-1 or a 1:1 ortholog thereof." [PMID:8536644, PRO:CNA]

organism-sequence


PR:Q13324-1
corticotropin-releasing factor receptor 2 isoform alpha (human)
hCRHR2/iso:alpha
"A corticotropin-releasing factor receptor 2 isoform alpha that is encoded in the genome of human." [PMID:8536644, PRO:CNA]

sequence


PR:000026081
corticotropin-releasing factor receptor 2 isoform beta
CRHR2/iso:beta
"A corticotropin-releasing factor receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-2 or a 1:1 ortholog thereof." [PMID:9199241, PRO:CNA]

organism-sequence


PR:Q13324-2
corticotropin-releasing factor receptor 2 isoform beta (human)
hCRHR2/iso:beta
"A corticotropin-releasing factor receptor 2 isoform beta that is encoded in the genome of human." [PMID:9199241, PRO:CNA]

organism-sequence


PR:Q60748-2
corticotropin-releasing factor receptor 2 isoform beta (mouse)
mCRHR2/iso:beta
"A corticotropin-releasing factor receptor 2 isoform beta that is encoded in the genome of mouse." [PMID:7708757, PRO:HJD]
Yes
sequence


PR:000026083
corticotropin-releasing factor receptor 2 isoform gamma
CRHR2/iso:gamma
"A corticotropin-releasing factor receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13324-3 or a 1:1 ortholog thereof." [PMID:9717834, PRO:CNA]

organism-sequence


PR:Q13324-3
corticotropin-releasing factor receptor 2 isoform gamma (human)
hCRHR2/iso:gamma
"A corticotropin-releasing factor receptor 2 isoform gamma that is encoded in the genome of human." [PMID:9717834, PRO:CNA]

sequence


PR:000026086
corticotropin-releasing factor receptor 2 isoform iv-beta
CRHR2/iso:iv-beta
"A corticotropin-releasing factor receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C0K3M3 or a 1:1 ortholog thereof. This sequence corresponds to the isoform beta with an insertion that encodes to includes a unique C-terminal cytoplasmic tail." [PRO:HJD]

organism-sequence


PR:C0K3M3
corticotropin-releasing factor receptor 2 isoform iv-beta (mouse)
mCRHR2/iso:iv-beta
"A corticotropin-releasing factor receptor 2 isoform iv-beta that is encoded in the genome of mouse." [PMID:7708757, PRO:HJD]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:C0K3M3 mCRHR2/iso:iv-beta acts_upstream_of_or_withinGO:0043950 positive regulation of cAMP-mediated signaling MGI_ref:3850921; PMID:19246489
GO:0043951 negative regulation of cAMP-mediated signaling MGI_ref:3850921; PMID:19246489
located_inGO:0005783 endoplasmic reticulum MGI_ref:3850921; PMID:19246489
GO:0005794 Golgi apparatus MGI_ref:3850921; PMID:19246489
NOT GO:0009986 cell surface MGI_ref:3850921; PMID:19246489
PR:Q60748-2 mCRHR2/iso:beta acts_upstream_of_or_withinGO:0043950 positive regulation of cAMP-mediated signaling PMID:19246489
located_inGO:0009986 cell surface MGI_ref:3850921; PMID:19246489