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Protein Ontology report - histone H3-like centromeric protein A
PR:000005323 - http://purl.obolibrary.org/obo/PR_000005323
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005323   
  PRO namehistone H3-like centromeric protein A 
  Synonyms
PRO-Short-label: EXACT:CENPA
Other: EXACT:centromere autoantigen A
  Definition"A core histone that is a translation product of the human CENPA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000043452 core histone
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000005323

histone H3-like centromeric protein A

CENPA


"A core histone that is a translation product of the human CENPA gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O35216

histone H3-like centromeric protein A (mouse)

mCENPA


"A histone H3-like centromeric protein A that is encoded in the genome of mouse." [OMA:O35216, PRO:DNx]


organism-gene



PR:P49450

histone H3-like centromeric protein A (human)

hCENPA


"A histone H3-like centromeric protein A that is encoded in the genome of human." [PMID:15592459, PRO:KER]

Yes

organism-sequence



PR:P49450-1

histone H3-like centromeric protein A isoform h1 (human)

hCENPA/iso:h1


"A histone H3-like centromeric protein A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49450-1." [PRO:DNx, UniProtKB:P49450]


organism-sequence



PR:P49450-2

histone H3-like centromeric protein A isoform h2 (human)

hCENPA/iso:h2


"A histone H3-like centromeric protein A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49450-2." [PRO:DNx, UniProtKB:P49450]


organism-modification



PR:000035364

histone H3-like centromeric protein A, initiator methionine removed phosphorylated 1 (human)

hCENPA/InitMet-/Phos:1


"A histone H3-like centromeric protein A, initiator methionine removed phosphorylated 1 in human. UniProtKB:P49450, 2-140, Ser-7, MOD:00046." [HIstome_var_Hs:Histone_H3-like_centromeric_protein_A, PMID:11756469, PMID:14667408, PMID:15592459, PRO:KER]


organism-modification



PR:000045801

histone H3-like centromeric protein A phosphorylated 1 (human)

hCENPA/Phos:1


"A histone H3-like centromeric protein A (human) that has been phosphorylated on the residue at the position equivalent to Ser-68 of the amino acid sequence represented by UniProtKB:P49450-1. Example: UniProtKB:P49450-1, Ser-68, MOD:00046." [iPTMnet:P49450, PMID:25556658]


organism-modification



PR:000067721

histone H3-like centromeric protein A phosphorylated 2 (human)

hCENPA/Phos:2


"A histone H3-like centromeric protein A (human) that has been phosphorylated on the residue at the position equivalent to Thr-120 of the amino acid sequence represented by UniProtKB:P49450-1. Example: UniProtKB:P49450-1, Thr-120, MOD:00047." [IEDB_epitope:2146171, PRO:DNx]


organism-gene



PR:Q6XXM1

histone H3-like centromeric protein A (chicken)

chick-CENPA


"A histone H3-like centromeric protein A that is encoded in the genome of chicken." [OMA:Q6XXM1, PRO:DNx]


organism-gene



PR:Q803H4

histone H3-like centromeric protein A (zebrafish)

z-CENPA


"A histone H3-like centromeric protein A that is encoded in the genome of zebrafish." [PRO:DNx]


modification



PR:000035363

histone H3-like centromeric protein A, initiator methionine removed phosphorylated 1

CENPA/InitMet-/Phos:1


"A histone H3-like centromeric protein A that has been phosphorylated on the residue at the position equivalent to Ser-7 of the amino acid sequence represented by UniProtKB:P49450. Example: UniProtKB:P49450, 2-140, Ser-7, MOD:00046." [PMID:15592459, PRO:DAN, PRO:KER]


organism-modification



PR:000035364

histone H3-like centromeric protein A, initiator methionine removed phosphorylated 1 (human)

hCENPA/InitMet-/Phos:1


"A histone H3-like centromeric protein A, initiator methionine removed phosphorylated 1 in human. UniProtKB:P49450, 2-140, Ser-7, MOD:00046." [HIstome_var_Hs:Histone_H3-like_centromeric_protein_A, PMID:11756469, PMID:14667408, PMID:15592459, PRO:KER]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P49450 hCENPA enablesGO:0005515 protein binding with PR:P68431 H3C1 BioGRID:BG-608929
GO:0005515 protein binding with PR:Q96GD4 AIK2 BioGRID:BG-608929
located_inGO:0000776 kinetochore PMID:15592459