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Protein Ontology report - borealin
PR:000005226 - http://purl.obolibrary.org/obo/PR_000005226
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005226   
  PRO nameborealin 
  Synonyms
PRO-Short-label: EXACT:CDCA8
Gene-based: RELATED:PESCRG3
Other: EXACT:cell division cycle-associated protein 8 | dasra-B | MESrg | pluripotent embryonic stem cell-related gene 3 protein
  Definition"A protein that is a translation product of the human CDCA8 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000005226

borealin

CDCA8


"A protein that is a translation product of the human CDCA8 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q53HL2

borealin (human)

hCDCA8


"A borealin that is encoded in the genome of human." [PMID:20929775, PRO:KER]

Yes

organism-modification



PR:000046668

borealin sumoylated form (human)

hCDCA8/SumoLys+


"A borealin (human) that includes at least one sumoylated lysine. UniProtKB:Q53HL2, MOD:01149." [PRO:DNx, Reactome:R-HSA-4655328]


organism-modification



PR:000065367

borealin methylated 1 (human)

hCDCA8/Me:1


"A borealin (human) that has been methylated on the residue at the position equivalent to Cys-273 of the amino acid sequence represented by UniProtKB:Q53HL2. UniProtKB:Q53HL2, Cys-273, MOD:00660." [IEDB_epitope:1001765, IEDB_epitope:1001766, IEDB_epitope:1042509, PRO:DNx]


organism-gene



PR:Q5XLR4

borealin (zebrafish)

z-CDCA8


"A borealin that is encoded in the genome of zebrafish." [OMA:Q5XLR4, PRO:DNx]


organism-gene



PR:Q6AXW0

borealin (rat)

rCDCA8


"A borealin that is encoded in the genome of rat." [OMA:Q6AXW0, PRO:DNx]


organism-gene



PR:Q8BHX3

borealin (mouse)

mCDCA8


"A borealin that is encoded in the genome of mouse." [OMA:Q8BHX3, PRO:DNx]


organism-sequence



PR:Q8BHX3-1

borealin isoform m1 (mouse)

mCDCA8/iso:m1


"A borealin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BHX3-1." [PRO:DNx, UniProtKB:Q8BHX3]


organism-sequence



PR:Q8BHX3-2

borealin isoform m2 (mouse)

mCDCA8/iso:m2


"A borealin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BHX3-2." [PRO:DNx, UniProtKB:Q8BHX3]


organism-sequence



PR:Q8BHX3-3

borealin isoform m3 (mouse)

mCDCA8/iso:m3


"A borealin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BHX3-3." [PRO:DNx, UniProtKB:Q8BHX3]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q53HL2 hCDCA8 enablesGO:0005515 protein binding with PR:O15392 API4 BioGRID:BG-251069; IntAct:EBI-1555222
GO:0005515 protein binding with PR:Q5FBB7 hSGO1 BioGRID:BG-251069; IntAct:EBI-1555222
GO:0005515 protein binding with PR:Q71DI3 H3-clustered histone 13 (human) BioGRID:BG-251069; IntAct:EBI-1555222
GO:0005515 protein binding with PR:Q96GD4 AIK2 BioGRID:BG-251069; IntAct:EBI-1555222
GO:0005515 protein binding with PR:Q9NQS7 hINCENP BioGRID:BG-251069; IntAct:EBI-1555222
located_inGO:0000779 condensed chromosome, centromeric region PMID:20929775