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Protein Ontology report - G1/S-specific cyclin-E1
PR:000005125 - http://purl.obolibrary.org/obo/PR_000005125
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005125   
  PRO nameG1/S-specific cyclin-E1 
  Synonyms
PRO-Short-label: EXACT:CCNE1
Gene-based: CCNE (BROAD)
  Definition"A cyclin-E that is a translation product of the human CCNE1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000044430 cyclin-E
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence3                                                  Organism-Sequence 4                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000005125

G1/S-specific cyclin-E1

CCNE1


"A cyclin-E that is a translation product of the human CCNE1 gene or a 1:1 ortholog thereof." [PRO:DNx]


Yes
organism-gene



PR:P24864

G1/S-specific cyclin-E1 (human)

hCCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:P24864-1

G1/S-specific cyclin-E1 isoform E1L (human)

hCCNE1/iso:E1L


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:P24864-2

G1/S-specific cyclin-E1 isoform E1S (human)

hCCNE1/iso:E1S


"A G1/S-specific cyclin-E1 isoform 2 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:P24864-3

G1/S-specific cyclin-E1 isoform 3 (human)

hCCNE1/iso:3


"A G1/S-specific cyclin-E1 isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000025637

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)

hCCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 in human. UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:JAN]

Yes

organism-modification



PR:000066039

G1/S-specific cyclin-E1 cysteinylated 1 (human)

hCCNE1/Cyst:1


"A G1/S-specific cyclin-E1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-156 of the amino acid sequence represented by UniProtKB:P24864-1. Example: UniProtKB:P24864-1, Cys-156, MOD:00765." [IEDB_epitope:1593104, PRO:DNx]


organism-gene



PR:P39949

G1/S-specific cyclin-E1 (rat)

rCCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of rat." [OMA:P39949, PRO:DNx]


organism-gene



PR:P47794

G1/S-specific cyclin-E1 (zebrafish)

z-CCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of zebrafish." [PRO:DNx]


organism-gene



PR:P49707

G1/S-specific cyclin-E1 (chicken)

chick-CCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of chicken." [OMA:P49707, PRO:DNx]


organism-gene



PR:Q61457

G1/S-specific cyclin-E1 (mouse)

mCCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of mouse." [OMA:Q61457, PRO:DNx]


organism-sequence



PR:Q61457-1

G1/S-specific cyclin-E1 isoform 1 (mouse)

mCCNE1/iso:1


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]


sequence



PR:000025612

G1/S-specific cyclin-E1 isoform 1

CCNE1/iso:1


"A G1/S-specific cyclin-E1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24864-1 or a 1:1 ortholog thereof." [PRO:JAN]


organism-sequence



PR:P24864-1

G1/S-specific cyclin-E1 isoform E1L (human)

hCCNE1/iso:E1L


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:Q61457-1

G1/S-specific cyclin-E1 isoform 1 (mouse)

mCCNE1/iso:1


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]


sequence



PR:000025614

G1/S-specific cyclin-E1 isoform 2

CCNE1/iso:2


"A G1/S-specific cyclin-E1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24864-2 or a 1:1 ortholog thereof. This isoform lacks a region of around 50 residues within the cyclin box." [PRO:JAN]


organism-sequence



PR:P24864-2

G1/S-specific cyclin-E1 isoform E1S (human)

hCCNE1/iso:E1S


"A G1/S-specific cyclin-E1 isoform 2 that is encoded in the genome of human." [PRO:JAN]


sequence



PR:000025616

G1/S-specific cyclin-E1 isoform 3

CCNE1/iso:3


"A G1/S-specific cyclin-E1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24864-3 or a 1:1 ortholog thereof." [PRO:JAN]


organism-sequence



PR:P24864-3

G1/S-specific cyclin-E1 isoform 3 (human)

hCCNE1/iso:3


"A G1/S-specific cyclin-E1 isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000025637

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)

hCCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 in human. UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:JAN]

Yes

modification



PR:000025618

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1

CCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 that has been phosphorylated by CDK2. Example: UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:DAN, PRO:JAN]


organism-modification



PR:000025637

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)

hCCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 in human. UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:JAN]

Yes

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CCNE1 forms found in complexes   

CCNE1 Component
Complexes
PR:000005125 CCNE1 PR:000026745 cyclin E1:Cdk2 complex
PR:000027141 cyclin E1:Cdk2 complex phosphorylated form
PR:P24864 hCCNE1 PR:000026768 cyclin E1:Cdk2 complex (human)
PR:000027151 cyclin E1:Cdk2 complex phosphorylated form (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025637 hCCNE1/iso:3/Phos:1
UniProtKB:P24864-3, Ser-384, MOD:00046
enablesGO:0005515 protein binding with PR:Q13526 hPIN1 PMID:16223725