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Protein Ontology report - beta-secretase 2
PR:000004616 - http://purl.obolibrary.org/obo/PR_000004616
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000004616   
  PRO namebeta-secretase 2 
  Synonyms
PRO-Short-label: EXACT:BACE2
Gene-based: RELATED:AEPLC | ALP56 | ASP21 | CDA13 | UNQ418/PRO852
Other: EXACT:Asp 1 | ASP1 | aspartic-like protease 56 kDa | aspartyl protease 1 | beta-site amyloid precursor protein cleaving enzyme 2 | beta-site APP cleaving enzyme 2 | down region aspartic protease | DRAP | memapsin-1 | membrane-associated aspartic protease 1 | theta-secretase
  Definition"A protein that is a translation product of the human BACE2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=Alzforum. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 7                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2331
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004616
beta-secretase 2
BACE2
"A protein that is a translation product of the human BACE2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q6IE75
beta-secretase 2 (rat)
rBACE2
"A beta-secretase 2 that is encoded in the genome of rat." [OMA:Q6IE75, PRO:DNx]

organism-sequence


PR:Q6IE75-1
beta-secretase 2 isoform 1 (rat)
rBACE2/iso:1
"A beta-secretase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:Q9JL18
beta-secretase 2 (mouse)
mBACE2
"A beta-secretase 2 that is encoded in the genome of mouse." [OMA:Q9JL18, PRO:DNx]

organism-sequence


PR:Q9JL18-1
beta-secretase 2 isoform 1 (mouse)
mBACE2/iso:1
"A beta-secretase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:Q9Y5Z0
beta-secretase 2 (human)
hBACE2
"A beta-secretase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y5Z0]

organism-sequence


PR:Q9Y5Z0-1
beta-secretase 2 isoform h1 (human)
hBACE2/iso:h1
"A beta-secretase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z0-1." [PRO:DNx, UniProtKB:Q9Y5Z0]

organism-sequence


PR:Q9Y5Z0-2
beta-secretase 2 isoform h2 (human)
hBACE2/iso:h2
"A beta-secretase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z0-2." [PRO:DNx, UniProtKB:Q9Y5Z0]

organism-sequence


PR:Q9Y5Z0-3
beta-secretase 2 isoform h3 (human)
hBACE2/iso:h3
"A beta-secretase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z0-3." [PRO:DNx, UniProtKB:Q9Y5Z0]

organism-sequence


PR:Q9Y5Z0-4
beta-secretase 2 isoform h4 (human)
hBACE2/iso:h4
"A beta-secretase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z0-4." [PRO:DNx, UniProtKB:Q9Y5Z0]

organism-sequence


PR:Q9Y5Z0-5
beta-secretase 2 isoform h5 (human)
hBACE2/iso:h5
"A beta-secretase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Z0-5." [PRO:DNx, UniProtKB:Q9Y5Z0]

organism-modification


PR:000058396
beta-secretase 2 O-glycosylated 1 (human)
hBACE2/OGlyco:1
"A beta-secretase 2 (human) that has been O-glycosylated at the residue equivalent to Ser-70 of the amino acid sequence represented by UniProtKB:Q9Y5Z0-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9Y5Z0-1, Ser-70, MOD:00002~GNO:G43417UB." [GlyGen:Q9Y5Z0-1, PMID:30459171, PRO:DNx]

sequence


PR:000043437
beta-secretase 2 isoform 1
BACE2/iso:1
"A beta-secretase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JL18-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:Q6IE75-1
beta-secretase 2 isoform 1 (rat)
rBACE2/iso:1
"A beta-secretase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:Q9JL18-1
beta-secretase 2 isoform 1 (mouse)
mBACE2/iso:1
"A beta-secretase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

modification


PR:000019113
beta-secretase 2 proteolytic cleavage product
BACE2/ClvPrd
"A beta-secretase 2 that has been processed by proteolytic cleavage." [PRO:DNx]