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Protein Ontology report - beta-2-microglobulin
PR:000004580 - http://purl.obolibrary.org/obo/PR_000004580
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004580   
  PRO namebeta-2-microglobulin 
  Synonyms
PRO-Short-label: EXACT:B2M
Gene-based: RELATED:CDABP0092 | HDCMA22P
  Definition"A protein that is a translation product of the human B2M gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004580
beta-2-microglobulin
B2M
"A protein that is a translation product of the human B2M gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P01887
beta-2-microglobulin (mouse)
mB2M
"A beta-2-microglobulin that is encoded in the genome of mouse." [OMA:P01887, PRO:DNx]

organism-sequence


PR:P01887-1
beta-2-microglobulin isoform 1 (mouse)
mB2M/iso:1
"A beta-2-microglobulin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-modification


PR:000065715
beta-2-microglobulin deaminated 1 (mouse)
mB2M/Deam:1
"A beta-2-microglobulin (mouse) that has been deaminated on the residue at the position equivalent to Gln-58 of the amino acid sequence represented by UniProtKB:P01887. UniProtKB:P01887, Gln-58, MOD:00685." [IEDB_epitope:2138071, PRO:DNx]

organism-gene


PR:P07151
beta-2-microglobulin (rat)
rB2M
"A beta-2-microglobulin that is encoded in the genome of rat." [OMA:P07151, PRO:DNx]

organism-gene


PR:P21611
beta-2-microglobulin (chicken)
chick-B2M
"A beta-2-microglobulin that is encoded in the genome of chicken." [OMA:P21611, PRO:DNx]

organism-gene


PR:P61769
beta-2-microglobulin (human)
hB2M
"A beta-2-microglobulin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P61769]

organism-sequence


PR:P61769-1
beta-2-microglobulin isoform 1 (human)
hB2M/iso:1
"A beta-2-microglobulin isoform 1 that is encoded in the genome of human." [PMID:17968930, SALO:AJ]
Yes
organism-modification


PR:000036227
beta-2-microglobulin acetylated 1 (human)
hB2M/Ac:1
"A beta-2-microglobulin that is N-terminal Met acetylated in human. UniProtKB:P61769, Met-1, MOD:00058." [TDR:1687]

organism-modification


PR:000046452
beta-2-microglobulin, signal peptide removed form (human)
hB2M/SigPep-
"A beta-2-microglobulin (human) that has had the signal peptide removed. UniProtKB:P61769, 21-119." [PRO:DNx, Reactome:R-HSA-1236827, Reactome:R-HSA-1236891, Reactome:R-HSA-1302721, Reactome:R-HSA-167743, Reactome:R-HSA-182298, Reactome:R-HSA-8863880, Reactome:R-HSA-983063, Reactome:R-HSA-983378, Reactome:R-HSA-983403]

organism-modification


PR:000065861
beta-2-microglobulin methylated 1 (human)
hB2M/Me:1
"A beta-2-microglobulin (human) that has been methylated on the residue at the position equivalent to Cys-100 of the amino acid sequence represented by UniProtKB:P61769. UniProtKB:P61769, Cys-100, MOD:00660." [IEDB_epitope:1004234, IEDB_epitope:1060527, PRO:DNx]

organism-modification


PR:000067733
beta-2-microglobulin deaminated 1 (human)
hB2M/Deam:1
"A beta-2-microglobulin (human) that has been deaminated on the residue at the position equivalent to Gln-22 of the amino acid sequence represented by UniProtKB:P61769. UniProtKB:P61769, Gln-22, MOD:00685." [IEDB_epitope:1584948, IEDB_epitope:1584951, PRO:DNx]

organism-modification


PR:000070588
beta-2-microglobulin deaminated 2 (human)
hB2M/Deam:2
"A beta-2-microglobulin (human) that has been deaminated on the residue at the position equivalent to Asn-41 of the amino acid sequence represented by UniProtKB:P61769. UniProtKB:P61769, Asn-41, MOD:00684." [IEDB_epitope:422398, PRO:DNx]

organism-modification


PR:000070974
beta-2-microglobulin cysteinylated 1 (human)
hB2M/Cyst:1
"A beta-2-microglobulin (human) that has been cysteinylated on the residue at the position equivalent to Cys-100 of the amino acid sequence represented by UniProtKB:P61769. UniProtKB:P61769, Cys-100, MOD:00765." [IEDB_epitope:2117995, IEDB_epitope:2130434, IEDB_epitope:2130435, IEDB_epitope:2130436, PRO:DNx]

organism-modification


PR:000074380
beta-2-microglobulin deaminated 3 (human)
hB2M/Deam:3
"A beta-2-microglobulin (human) that has been deaminated on the residue at the position equivalent to Gln-28 of the amino acid sequence represented by UniProtKB:P61769. UniProtKB:P61769, Gln-28, MOD:00685." [IEDB_epitope:1584952, IEDB_epitope:1590778, PRO:DNx]

organism-modification


PR:000083988
beta-2-microglobulin deaminated 4 (human)
hB2M/Deam:4
"A beta-2-microglobulin (human) that has been deaminated on the residue at the position equivalent to Asn-37 of the amino acid sequence represented by UniProtKB:P61769. UniProtKB:P61769, Asn-37, MOD:00684." [IEDB_epitope:1575436, IEDB_epitope:1575437, IEDB_epitope:1583445, IEDB_epitope:1586039, IEDB_epitope:1590777, IEDB_epitope:1590779, IEDB_epitope:1592970, IEDB_epitope:1594488, PRO:DNx]

organism-gene


PR:Q04475
beta-2-microglobulin (zebrafish)
z-B2M
"A beta-2-microglobulin that is encoded in the genome of zebrafish." [PRO:DNx]

sequence


PR:000025659
beta-2-microglobulin isoform 1
B2M/iso:1
"A beta-2-microglobulin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61769-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P01887-1
beta-2-microglobulin isoform 1 (mouse)
mB2M/iso:1
"A beta-2-microglobulin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-sequence


PR:P61769-1
beta-2-microglobulin isoform 1 (human)
hB2M/iso:1
"A beta-2-microglobulin isoform 1 that is encoded in the genome of human." [PMID:17968930, SALO:AJ]
Yes
modification


PR:000026597
beta-2-microglobulin isoform 1, signal peptide removed form
B2M/iso:1/SigPep-
"A beta-2-microglobulin isoform 1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000019109
beta-2-microglobulin, signal peptide removed form
B2M/SigPep-
"A beta-2-microglobulin that has had the signal peptide removed." [PRO:DNx]

modification


PR:000026597
beta-2-microglobulin isoform 1, signal peptide removed form
B2M/iso:1/SigPep-
"A beta-2-microglobulin isoform 1 that has had the signal peptide removed." [PRO:DNx]

organism-modification


PR:000046452
beta-2-microglobulin, signal peptide removed form (human)
hB2M/SigPep-
"A beta-2-microglobulin (human) that has had the signal peptide removed. UniProtKB:P61769, 21-119." [PRO:DNx, Reactome:R-HSA-1236827, Reactome:R-HSA-1236891, Reactome:R-HSA-1302721, Reactome:R-HSA-167743, Reactome:R-HSA-182298, Reactome:R-HSA-8863880, Reactome:R-HSA-983063, Reactome:R-HSA-983378, Reactome:R-HSA-983403]

modification


PR:000019110
beta-2-microglobulin proteolytic cleavage product
B2M/ClvPrd
"A beta-2-microglobulin that has been processed by proteolytic cleavage." [PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P61769-1 hB2M/iso:1 located_inCHEBI:59163 biomarker PMID:17968930