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Protein Ontology report - aurora kinase A
PR:000004515 - http://purl.obolibrary.org/obo/PR_000004515
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004515   
  PRO nameaurora kinase A 
  Synonyms
PRO-Short-label: EXACT:AURKA
Gene-based: RELATED:AIK | AIRK1 | ARK1 | AURA | BTAK | STK15 | STK6
Other: EXACT:ARK-1 | aurora 2 | aurora family kinase 1 | aurora-related kinase 1 | aurora/IPL1-related kinase 1 | breast tumor-amplified kinase | ipl1- and aurora-related kinase 1 | serine/threonine-protein kinase 15 | serine/threonine-protein kinase 6 | serine/threonine-protein kinase aurora-A | serine/threonine-protein kinase Ayk1
RELATED:Ayk1 | Iak1
  Definition"An aurora kinase that is a translation product of the human AURKA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000035365 aurora kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1936
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000004515

aurora kinase A

AURKA


"An aurora kinase that is a translation product of the human AURKA gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O14965

aurora kinase A (human)

hAURKA


"An aurora kinase A that is encoded in the genome of human." [PRO:KER]

Yes

organism-modification



PR:000045573

aurora kinase A phosphorylated 1 (human)

hAURKA/Phos:1


"An aurora kinase A (human) that has been phosphorylated at Thr-288. UniProtKB:O14965, Thr-288, MOD:00047." [iPTMnet:O14965, PMID:11039908]


organism-modification



PR:000046439

aurora kinase A sumoylated 1 (human)

hAURKA/Sumo:1


"An aurora kinase A (human) that has been post-translationally modified to include sumoylated lysine at position 258 of the amino acid sequence represented by UniProtKB:O14965. UniProtKB:O14965, Lys-258, MOD:01149." [PRO:DNx, Reactome:R-HSA-4655367]


organism-modification



PR:000064814

aurora kinase A ubiquitinated form (human)

hAURKA/UbiqLys+


"An aurora kinase A (human) that includes at least one ubiquitinated lysine. UniProtKB:O14965, MOD:01148." [PRO:DNx, Reactome:R-HSA-8854040]


organism-modification



PR:000084713

aurora kinase A hydroxylated 1 (human)

hAURKA/Hy:1


"An aurora kinase A (human) that has been hydroxylated on the residue at the position equivalent to Trp-277 of the amino acid sequence represented by UniProtKB:O14965. UniProtKB:O14965, Trp-277, MOD:01622." [IEDB_epitope:1319516, PRO:DNx]


organism-gene



PR:P59241

aurora kinase A (rat)

rAURKA


"An aurora kinase A that is encoded in the genome of rat." [PRO:DAN]


organism-gene



PR:P97477

aurora kinase A (mouse)

mAURKA


"An aurora kinase A that is encoded in the genome of mouse." [OMA:P97477, PRO:DNx]


organism-sequence



PR:P97477-1

aurora kinase A isoform m1 (mouse)

mAURKA/iso:m1


"An aurora kinase A (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97477-1." [PRO:DNx, UniProtKB:P97477]


organism-sequence



PR:P97477-2

aurora kinase A isoform m2 (mouse)

mAURKA/iso:m2


"An aurora kinase A (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97477-2." [PRO:DNx, UniProtKB:P97477]


organism-gene



PR:Q54WX4

aurora kinase (Dictyostelium discoideum)

Dicty-AURKA


"An aurora kinase A that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54WX4, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O14965 hAURKA enablesGO:0005515 protein binding with PR:Q9H4B4 CNK PMID:15190214
located_inGO:0000922 spindle pole PMID:15190214
GO:0005813 centrosome PMID:15190214
GO:0030496 midbody PMID:15190214