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Protein Ontology report - DNA repair nuclease/redox regulator APEX1
PR:000004127 - http://purl.obolibrary.org/obo/PR_000004127
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000004127   
  PRO nameDNA repair nuclease/redox regulator APEX1 
  Synonyms
PRO-Short-label: EXACT:APEX1
Gene-based: RELATED:APE | APE1 | APEX | APX | HAP1 | REF1
Other: EXACT:AP endonuclease 1 | APEN | APEX nuclease | apurinic-apyrimidinic endonuclease 1 | DNA-(apurinic or apyrimidinic site) endonuclease | DNA-(apurinic or apyrimidinic site) lyase | protein REF-1 | redox factor-1 | REF-1
  Definition"A protein that is a translation product of the human APEX1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000004127

DNA repair nuclease/redox regulator APEX1

APEX1


"A protein that is a translation product of the human APEX1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A0MTA1

DNA repair nuclease APEX1 (zebrafish)

z-APEX1


"A DNA repair nuclease/redox regulator APEX1 that is encoded in the genome of zebrafish." [OMA:A0MTA1, PRO:DNx]


organism-gene



PR:P27695

DNA repair nuclease/redox regulator APEX1 (human)

hAPEX1


"A DNA repair nuclease/redox regulator APEX1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27695]


organism-modification



PR:000046353

DNA repair nuclease/redox regulator APEX1, initiator methionine removed form (human)

hAPEX1/InitMet-


"A DNA repair nuclease/redox regulator APEX1 (human) that has had the initiator methionine removed. UniProtKB:P27695, 2-318." [PRO:DNx, Reactome:R-HSA-50119]


organism-modification



PR:000069197

DNA repair nuclease/redox regulator APEX1 methylated 1 (human)

hAPEX1/Me:1


"A DNA repair nuclease/redox regulator APEX1 (human) that has been methylated on the residue at the position equivalent to Cys-310 of the amino acid sequence represented by UniProtKB:P27695. UniProtKB:P27695, Cys-310, MOD:00660." [IEDB_epitope:1005127, PRO:DNx]


organism-modification



PR:000075114

DNA repair nuclease/redox regulator APEX1 deaminated 1 (human)

hAPEX1/Deam:1


"A DNA repair nuclease/redox regulator APEX1 (human) that has been deaminated on the residue at the position equivalent to Asn-259 of the amino acid sequence represented by UniProtKB:P27695. UniProtKB:P27695, Asn-259, MOD:00684." [IEDB_epitope:1355979, PRO:DNx]


organism-modification



PR:000082098

DNA repair nuclease/redox regulator APEX1 methylated 2 (human)

hAPEX1/Me:2


"A DNA repair nuclease/redox regulator APEX1 (human) that has been methylated on the residue at the position equivalent to Cys-138 of the amino acid sequence represented by UniProtKB:P27695. UniProtKB:P27695, Cys-138, MOD:00660." [IEDB_epitope:1044559, PRO:DNx]


organism-gene



PR:P28352

DNA repair nuclease/redox regulator APEX1 (mouse)

mAPEX1


"A DNA repair nuclease/redox regulator APEX1 that is encoded in the genome of mouse." [OMA:P28352, PRO:DNx]


organism-sequence



PR:P28352-1

DNA repair nuclease/redox regulator APEX1 isoform 1 (mouse)

mAPEX1/iso:1


"A DNA repair nuclease/redox regulator APEX1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000070923

DNA repair nuclease/redox regulator APEX1 deaminated 1 (mouse)

mAPEX1/Deam:1


"A DNA repair nuclease/redox regulator APEX1 (mouse) that has been deaminated on the residue at the position equivalent to Gln-244 of the amino acid sequence represented by UniProtKB:P28352. UniProtKB:P28352, Gln-244, MOD:00685." [IEDB_epitope:2136016, IEDB_epitope:2136017, IEDB_epitope:2136129, PRO:DNx]


organism-modification



PR:000078277

DNA repair nuclease/redox regulator APEX1 deaminated 2 (mouse)

mAPEX1/Deam:2


"A DNA repair nuclease/redox regulator APEX1 (mouse) that has been deaminated on the residue at the position equivalent to Asn-221 of the amino acid sequence represented by UniProtKB:P28352. UniProtKB:P28352, Asn-221, MOD:00684." [IEDB_epitope:2135976, PRO:DNx]


organism-gene



PR:P43138

DNA repair nuclease/redox regulator APEX1 (rat)

rAPEX1


"A DNA repair nuclease/redox regulator APEX1 that is encoded in the genome of rat." [OMA:P43138, PRO:DNx]


organism-sequence



PR:P43138-1

DNA repair nuclease/redox regulator APEX1 isoform 1 (rat)

rAPEX1/iso:1


"A DNA repair nuclease/redox regulator APEX1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P51173

DNA-(apurinic or apyrimidinic site) endonuclease (Dictyostelium discoideum)

Dicty-APEX1


"A DNA repair nuclease/redox regulator APEX1 that is encoded in the genome of Dictyostelium discoideum." [OMA:P51173, PRO:DNx]


sequence



PR:000039197

DNA repair nuclease/redox regulator APEX1 isoform 1

APEX1/iso:1


"A DNA repair nuclease/redox regulator APEX1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28352-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P28352-1

DNA repair nuclease/redox regulator APEX1 isoform 1 (mouse)

mAPEX1/iso:1


"A DNA repair nuclease/redox regulator APEX1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P43138-1

DNA repair nuclease/redox regulator APEX1 isoform 1 (rat)

rAPEX1/iso:1


"A DNA repair nuclease/redox regulator APEX1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


modification



PR:000019006

DNA repair nuclease/redox regulator APEX1, initiator methionine removed form

APEX1/InitMet-


"A DNA repair nuclease/redox regulator APEX1 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000046353

DNA repair nuclease/redox regulator APEX1, initiator methionine removed form (human)

hAPEX1/InitMet-


"A DNA repair nuclease/redox regulator APEX1 (human) that has had the initiator methionine removed. UniProtKB:P27695, 2-318." [PRO:DNx, Reactome:R-HSA-50119]