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Protein Ontology report - polyunsaturated fatty acid 5-lipoxygenase
PR:000003961 - http://purl.obolibrary.org/obo/PR_000003961
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000003961   
  PRO namepolyunsaturated fatty acid 5-lipoxygenase 
  Synonyms
PRO-Short-label: EXACT:ALOX5
Gene-based: RELATED:LOG5
Other: EXACT:5-lipoxygenase | 5-LO | arachidonate 5-lipoxygenase
  Definition"A protein that is a translation product of the human ALOX5 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 6                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1385
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003961
polyunsaturated fatty acid 5-lipoxygenase
ALOX5
"A protein that is a translation product of the human ALOX5 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P09917
polyunsaturated fatty acid 5-lipoxygenase (human)
hALOX5
"A polyunsaturated fatty acid 5-lipoxygenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P09917]

organism-sequence


PR:P09917-1
polyunsaturated fatty acid 5-lipoxygenase isoform 1 (human)
hALOX5/iso:1
"A polyunsaturated fatty acid 5-lipoxygenase isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:P09917-2
polyunsaturated fatty acid 5-lipoxygenase isoform h2 (human)
hALOX5/iso:h2
"A polyunsaturated fatty acid 5-lipoxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09917-2." [PRO:DNx, UniProtKB:P09917]

organism-sequence


PR:P09917-3
polyunsaturated fatty acid 5-lipoxygenase isoform h3 (human)
hALOX5/iso:h3
"A polyunsaturated fatty acid 5-lipoxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09917-3." [PRO:DNx, UniProtKB:P09917]

organism-sequence


PR:P09917-4
polyunsaturated fatty acid 5-lipoxygenase isoform h4 (human)
hALOX5/iso:h4
"A polyunsaturated fatty acid 5-lipoxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09917-4." [PRO:DNx, UniProtKB:P09917]

organism-sequence


PR:P09917-5
polyunsaturated fatty acid 5-lipoxygenase isoform h5 (human)
hALOX5/iso:h5
"A polyunsaturated fatty acid 5-lipoxygenase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09917-5." [PRO:DNx, UniProtKB:P09917]

organism-modification


PR:000046325
polyunsaturated fatty acid 5-lipoxygenase, initiator methionine removed phosphorylated 1 (human)
hALOX5/InitMet-/Phos:1
"A polyunsaturated fatty acid 5-lipoxygenase (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at position 272 of the amino acid sequence represented by UniProtKB:P09917. UniProtKB:P09917, 2-674, Ser-272, MOD:00046." [PRO:DNx, Reactome:R-HSA-2318765, Reactome:R-HSA-265276]

organism-modification


PR:000073170
polyunsaturated fatty acid 5-lipoxygenase methylated 1 (human)
hALOX5/Me:1
"A polyunsaturated fatty acid 5-lipoxygenase (human) that has been methylated on the residue at the position equivalent to Cys-301 of the amino acid sequence represented by UniProtKB:P09917-1. Example: UniProtKB:P09917-1, Cys-301, MOD:00660." [IEDB_epitope:1026963, PRO:DNx]

organism-modification


PR:000078850
polyunsaturated fatty acid 5-lipoxygenase methylated 2 (human)
hALOX5/Me:2
"A polyunsaturated fatty acid 5-lipoxygenase (human) that has been methylated on the residue at the position equivalent to Cys-311 of the amino acid sequence represented by UniProtKB:P09917-1. Example: UniProtKB:P09917-1, Cys-311, MOD:00660." [IEDB_epitope:1028050, PRO:DNx]

organism-gene


PR:P12527
polyunsaturated fatty acid 5-lipoxygenase (rat)
rALOX5
"A polyunsaturated fatty acid 5-lipoxygenase that is encoded in the genome of rat." [OMA:P12527, PRO:DNx]

organism-gene


PR:P48999
polyunsaturated fatty acid 5-lipoxygenase (mouse)
mALOX5
"A polyunsaturated fatty acid 5-lipoxygenase that is encoded in the genome of mouse." [OMA:P48999, PRO:DNx]

organism-sequence


PR:P48999-1
polyunsaturated fatty acid 5-lipoxygenase isoform 1 (mouse)
mALOX5/iso:1
"A polyunsaturated fatty acid 5-lipoxygenase isoform 1 that is encoded in the genome of mouse." [PMID:7629107, PRO:HJD]

Yes
sequence


PR:000027155
polyunsaturated fatty acid 5-lipoxygenase isoform 1
ALOX5/iso:1
"A polyunsaturated fatty acid 5-lipoxygenase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48999-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P09917-1
polyunsaturated fatty acid 5-lipoxygenase isoform 1 (human)
hALOX5/iso:1
"A polyunsaturated fatty acid 5-lipoxygenase isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:P48999-1
polyunsaturated fatty acid 5-lipoxygenase isoform 1 (mouse)
mALOX5/iso:1
"A polyunsaturated fatty acid 5-lipoxygenase isoform 1 that is encoded in the genome of mouse." [PMID:7629107, PRO:HJD]

Yes
modification


PR:000018962
polyunsaturated fatty acid 5-lipoxygenase, initiator methionine removed form
ALOX5/InitMet-
"A polyunsaturated fatty acid 5-lipoxygenase that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000046325
polyunsaturated fatty acid 5-lipoxygenase, initiator methionine removed phosphorylated 1 (human)
hALOX5/InitMet-/Phos:1
"A polyunsaturated fatty acid 5-lipoxygenase (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphoserine at position 272 of the amino acid sequence represented by UniProtKB:P09917. UniProtKB:P09917, 2-674, Ser-272, MOD:00046." [PRO:DNx, Reactome:R-HSA-2318765, Reactome:R-HSA-265276]

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ALOX5 forms found in complexes   

ALOX5 Component
 Complexes
PR:P48999ZDASHZ1 mALOX5/iso:1 PR:000027249 5-lipoxygenase complex (mouse)