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Protein Ontology report - tyrosine-protein kinase ABL1
PR:000003582 - http://purl.obolibrary.org/obo/PR_000003582
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003582   
  PRO nametyrosine-protein kinase ABL1 
  Synonyms
PRO-Short-label: EXACT:ABL1
Gene-based: RELATED:ABL | JTK7
Other: EXACT:abelson murine leukemia viral oncogene homolog 1 | Abelson tyrosine-protein kinase 1 | proto-oncogene c-Abl | proto-oncogene tyrosine-protein kinase ABL1
  Definition"A protein that is a translation product of the human ABL1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification1                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1923
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003582
tyrosine-protein kinase ABL1
ABL1
"A protein that is a translation product of the human ABL1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P00519
tyrosine-protein kinase ABL1 (human)
hABL1
"A tyrosine-protein kinase ABL1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00519]

organism-sequence


PR:P00519-1
tyrosine-protein kinase ABL1 isoform 1 (human)
hABL1/iso:1
"A tyrosine-protein kinase ABL1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:P00519-2
tyrosine-protein kinase ABL1 isoform 2 (human)
hABL1/iso:2
"A tyrosine-protein kinase ABL1 isoform 2 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000028614
tyrosine-protein kinase ABL1 isoform 2 acetylated 1 (human)
hABL1/iso:2/Ac:1
"A tyrosine-protein kinase ABL1 isoform 2 acetylated 1 in human. UniProtKB:P00519-2, Lys-730, MOD:00064." [KAT:P00519-2, PMID:16648821, PRO:PD]

organism-modification


PR:000044506
tyrosine-protein kinase ABL1 phosphorylated 1 (human)
hABL1/Phos:1
"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-735 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Thr-735, MOD:00047." [PMID:15696159, PMID:16888623, PRO:CNA]
Yes
organism-modification


PR:000046226
tyrosine-protein kinase ABL1 phosphorylated 2 (human)
hABL1/Phos:2
"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-446 of the amino acid sequence represented by UniProtKB:P00519. UniProtKB:P00519, Ser-446, MOD:00046." [PRO:DAN, Reactome:R-HSA-5686576]

organism-modification


PR:000075644
tyrosine-protein kinase ABL1 methylated 1 (human)
hABL1/Me:1
"A tyrosine-protein kinase ABL1 (human) that has been methylated on the residue at the position equivalent to Cys-1100 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Cys-1100, MOD:00660." [IEDB_epitope:1041130, PRO:DNx]

organism-modification


PR:000077670
tyrosine-protein kinase ABL1 deaminated 1 (human)
hABL1/Deam:1
"A tyrosine-protein kinase ABL1 (human) that has been deaminated on the residue at the position equivalent to Gln-1112 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Gln-1112, MOD:00685." [IEDB_epitope:1365553, PRO:DNx]

organism-modification


PR:000085814
tyrosine-protein kinase ABL1 phosphorylated 3 (human)
hABL1/Phos:3
"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-393 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Tyr-393, MOD:00048." [PRO:DNx, Reactome:R-HSA-9865161]

organism-modification


PR:000086246
tyrosine-protein kinase ABL1 phosphorylated 4 (human)
hABL1/Phos:4
"A tyrosine-protein kinase ABL1 (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-226 and Tyr-393 of the amino acid sequence represented by UniProtKB:P00519-1. Example: UniProtKB:P00519-1, Tyr-226/Tyr-393, MOD:00048." [PRO:DNx, Reactome:R-HSA-8942610, Reactome:R-HSA-8985251]

organism-gene


PR:P00520
tyrosine-protein kinase ABL1 (mouse)
mABL1
"A tyrosine-protein kinase ABL1 that is encoded in the genome of mouse." [OMA:P00520, PRO:DNx]

organism-sequence


PR:P00520-1
tyrosine-protein kinase ABL1 isoform I (mouse)
mABL1/iso:I
"A tyrosine-protein kinase ABL1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00520-1." [PRO:DNx, UniProtKB:P00520]

organism-sequence


PR:P00520-2
tyrosine-protein kinase ABL1 isoform II (mouse)
mABL1/iso:II
"A tyrosine-protein kinase ABL1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00520-2." [PRO:DNx, UniProtKB:P00520]

organism-sequence


PR:P00520-3
tyrosine-protein kinase ABL1 isoform III (mouse)
mABL1/iso:III
"A tyrosine-protein kinase ABL1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00520-3." [PRO:DNx, UniProtKB:P00520]

organism-sequence


PR:P00520-4
tyrosine-protein kinase ABL1 isoform IV (mouse)
mABL1/iso:IV
"A tyrosine-protein kinase ABL1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00520-4." [PRO:DNx, UniProtKB:P00520]

organism-gene


PR:P00522
tyrosine-protein kinase Abl (fruit fly)
fly-ABL1
"A tyrosine-protein kinase ABL1 that is encoded in the genome of fruit fly." [PANTHER:PTHR24418:SF144, PRO:DNx]

organism-gene


PR:P03949
tyrosine-protein kinase abl-1 (worm)
ABL1 (worm)
"A tyrosine-protein kinase ABL1 that is encoded in the genome of worm." [PANTHER:PTHR24418:SF144, PRO:DNx]

organism-sequence


PR:P03949-1
tyrosine-protein kinase abl-1 isoform a (worm)
ABL1/iso:a (worm)
"A tyrosine-protein kinase abl-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P03949-1." [PRO:DNx, UniProtKB:P03949]

organism-sequence


PR:P03949-2
tyrosine-protein kinase abl-1 isoform b (worm)
ABL1/iso:b (worm)
"A tyrosine-protein kinase abl-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P03949-2." [PRO:DNx, UniProtKB:P03949]

organism-sequence


PR:P03949-3
tyrosine-protein kinase abl-1 isoform c (worm)
ABL1/iso:c (worm)
"A tyrosine-protein kinase abl-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P03949-3." [PRO:DNx, UniProtKB:P03949]

sequence


PR:000028609
tyrosine-protein kinase ABL1 isoform 1
ABL1/iso:1
"A tyrosine-protein kinase ABL1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00519-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P00519-1
tyrosine-protein kinase ABL1 isoform 1 (human)
hABL1/iso:1
"A tyrosine-protein kinase ABL1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

sequence


PR:000028611
tyrosine-protein kinase ABL1 isoform 2
ABL1/iso:2
"A tyrosine-protein kinase ABL1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00519-2 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P00519-2
tyrosine-protein kinase ABL1 isoform 2 (human)
hABL1/iso:2
"A tyrosine-protein kinase ABL1 isoform 2 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000028614
tyrosine-protein kinase ABL1 isoform 2 acetylated 1 (human)
hABL1/iso:2/Ac:1
"A tyrosine-protein kinase ABL1 isoform 2 acetylated 1 in human. UniProtKB:P00519-2, Lys-730, MOD:00064." [KAT:P00519-2, PMID:16648821, PRO:PD]

modification


PR:000028613
tyrosine-protein kinase ABL1 isoform 2 acetylated 1
ABL1/iso:2/Ac:1
"A tyrosine-protein kinase ABL1 isoform 2 that is acetylated on a Lys residue located in the second nuclear localization signal (NLS2). Example: UniProtKB:P00519-2, Lys-730, MOD:00064." [KAT:P00519-2, PMID:16648821, PRO:PD]

organism-modification


PR:000028614
tyrosine-protein kinase ABL1 isoform 2 acetylated 1 (human)
hABL1/iso:2/Ac:1
"A tyrosine-protein kinase ABL1 isoform 2 acetylated 1 in human. UniProtKB:P00519-2, Lys-730, MOD:00064." [KAT:P00519-2, PMID:16648821, PRO:PD]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044506 hABL1/Phos:1
Example: UniProtKB:P00519-1, Thr-735, MOD:00047		 enablesGO:0071889 14-3-3 protein binding with PR:000044507 fam:14-3-3 (human) PMID:15696159
GO:0071889 14-3-3 protein binding with PR:P63104 hYWHAZ PMID:15696159
located_inGO:0005737 cytoplasm PMID:15696159