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Documentation
Protein Ontology report - serine/threonine-protein kinase LMTK1
PR:000003535 -
http://purl.obolibrary.org/obo/PR_000003535
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000003535
PRO name
serine/threonine-protein kinase LMTK1
Synonyms
PRO-Short-label
:
EXACT:
AATK
Gene-based
:
RELATED:
AATYK | KIAA0641 | LMR1 | LMTK1
Other
:
EXACT:
apoptosis-associated tyrosine kinase | brain apoptosis-associated tyrosine kinase | CDK5-binding protein | lemur tyrosine kinase 1 | p35-binding protein | p35BP
Definition
"A protein that is a translation product of the human AATK gene or a 1:1 ortholog thereof." [PRO:DNx]
PRO Category
gene
Parent
PR:000000001
protein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
3
Sequence
3
Organism-Sequence
7
Modification
3
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
IUPHARobj:1922
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
gene
PR:000003535
serine/threonine-protein kinase LMTK1
AATK
"A protein that is a translation product of the human AATK gene or a 1:1 ortholog thereof." [PRO:DNx]
organism-gene
PR:Q54RV3
serine/threonine-protein kinase pakG (Dictyostelium discoideum)
Dicty-AATK
"A serine/threonine-protein kinase LMTK1 that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]
organism-gene
PR:Q6ZMQ8
serine/threonine-protein kinase LMTK1 (human)
hAATK
"A serine/threonine-protein kinase LMTK1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6ZMQ8]
organism-sequence
PR:Q6ZMQ8-1
serine/threonine-protein kinase LMTK1 isoform h1 (human)
hAATK/iso:h1
"A serine/threonine-protein kinase LMTK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMQ8-1." [PRO:DNx, UniProtKB:Q6ZMQ8]
organism-sequence
PR:Q6ZMQ8-2
serine/threonine-protein kinase LMTK1 isoform h2 (human)
hAATK/iso:h2
"A serine/threonine-protein kinase LMTK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMQ8-2." [PRO:DNx, UniProtKB:Q6ZMQ8]
organism-sequence
PR:Q6ZMQ8-3
serine/threonine-protein kinase LMTK1 isoform h3 (human)
hAATK/iso:h3
"A serine/threonine-protein kinase LMTK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMQ8-3." [PRO:DNx, UniProtKB:Q6ZMQ8]
organism-gene
PR:Q80YE4
serine/threonine-protein kinase LMTK1 (mouse)
mAATK
"A serine/threonine-protein kinase LMTK1 that is encoded in the genome of mouse." [OMA:Q80YE4, PRO:DNx]
organism-sequence
PR:Q80YE4-1
serine/threonine-protein kinase LMTK1 isoform 1 (mouse)
mAATK/iso:1
"A serine/threonine-protein kinase LMTK1 isoform 1 that is encoded in the genome of mouse." [PMID:11314039, PRO:HJD]
Yes
organism-sequence
PR:Q80YE4-2
serine/threonine-protein kinase LMTK1 isoform 2 (mouse)
mAATK/iso:2
"A serine/threonine-protein kinase LMTK1 isoform 2 that is encoded in the genome of mouse." [PMID:9444961, PRO:HJD]
Yes
organism-modification
PR:000035696
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse)
mAATK/iso:2/Palm:1
"A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115." [PMID:18691334, PRO:KRC]
Yes
organism-modification
PR:000035698
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1 (mouse)
mAATK/iso:2/PalmPhos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115|Tyr-25/Tyr-46, MOD:00048." [PMID:18691334, PRO:KRC]
organism-modification
PR:000035700
serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse)
mAATK/iso:2/Phos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 in mouse. UniProtKB:Q80YE4-2, Ser-34, MOD:00046." [PMID:22573681, PRO:KRC]
Yes
organism-sequence
PR:Q80YE4-3
serine/threonine-protein kinase LMTK1 isoform 3 (mouse)
mAATK/iso:3
"A serine/threonine-protein kinase LMTK1 isoform 3 that is encoded in the genome of mouse." [PMID:17651901, PRO:HJD]
Yes
organism-sequence
PR:Q80YE4-4
serine/threonine-protein kinase LMTK1 isoform m4 (mouse)
mAATK/iso:m4
"A serine/threonine-protein kinase LMTK1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80YE4-4." [PRO:DNx, UniProtKB:Q80YE4]
sequence
PR:000035374
serine/threonine-protein kinase LMTK1 isoform 1
AATK/iso:1
"A serine/threonine-protein kinase LMTK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80YE4-1 or a 1:1 ortholog thereof." [PMID:11314039, PRO:HJD]
organism-sequence
PR:Q80YE4-1
serine/threonine-protein kinase LMTK1 isoform 1 (mouse)
mAATK/iso:1
"A serine/threonine-protein kinase LMTK1 isoform 1 that is encoded in the genome of mouse." [PMID:11314039, PRO:HJD]
Yes
sequence
PR:000035376
serine/threonine-protein kinase LMTK1 isoform 2
AATK/iso:2
"A serine/threonine-protein kinase LMTK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80YE4-2 or a 1:1 ortholog thereof." [PRO:HJD]
organism-sequence
PR:Q80YE4-2
serine/threonine-protein kinase LMTK1 isoform 2 (mouse)
mAATK/iso:2
"A serine/threonine-protein kinase LMTK1 isoform 2 that is encoded in the genome of mouse." [PMID:9444961, PRO:HJD]
Yes
organism-modification
PR:000035696
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse)
mAATK/iso:2/Palm:1
"A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115." [PMID:18691334, PRO:KRC]
Yes
organism-modification
PR:000035698
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1 (mouse)
mAATK/iso:2/PalmPhos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115|Tyr-25/Tyr-46, MOD:00048." [PMID:18691334, PRO:KRC]
organism-modification
PR:000035700
serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse)
mAATK/iso:2/Phos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 in mouse. UniProtKB:Q80YE4-2, Ser-34, MOD:00046." [PMID:22573681, PRO:KRC]
Yes
modification
PR:000035695
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1
AATK/iso:2/Palm:1
"A serine/threonine-protein kinase LMTK1 isoform 2 that has been palmitoylated on the Cys residues in the motif CLCCKK located at the N-terminal region. Example: UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115." [PMID:18691334, PRO:KRC]
organism-modification
PR:000035696
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 (mouse)
mAATK/iso:2/Palm:1
"A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115." [PMID:18691334, PRO:KRC]
Yes
modification
PR:000035697
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1
AATK/iso:2/PalmPhos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 that has been palmitoylated on the Cys residues in the motif CLCCKK located at the N-terminal region, and phosphorylated on two Tyr in Src family tyrosine kinases (SFKs) sites. Palmitoylation is necessary for the phosphorylation to occur. Example: UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115|Tyr-25/Tyr-46, MOD:00048." [PMID:18691334, PRO:CNA]
organism-modification
PR:000035698
serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1 (mouse)
mAATK/iso:2/PalmPhos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 palmitoylated and phosphorylated 1 in mouse. UniProtKB:Q80YE4-2, Cys-4/Cys-6/Cys-7, MOD:00115|Tyr-25/Tyr-46, MOD:00048." [PMID:18691334, PRO:KRC]
modification
PR:000035699
serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1
AATK/iso:2/Phos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 that been phosphorylated at the Ser residue in the sequence QGSPA within the N-terminal region. Example: UniProtKB:Q80YE4-2, Ser-34, MOD:00046." [PMID:20422042, PMID:22573681, PRO:CNA]
organism-modification
PR:000035700
serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 (mouse)
mAATK/iso:2/Phos:1
"A serine/threonine-protein kinase LMTK1 isoform 2 phosphorylated 1 in mouse. UniProtKB:Q80YE4-2, Ser-34, MOD:00046." [PMID:22573681, PRO:KRC]
Yes
sequence
PR:000035378
serine/threonine-protein kinase LMTK1 isoform 3
AATK/iso:3
"A serine/threonine-protein kinase LMTK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80YE4-3 or a 1:1 ortholog thereof." [PMID:17651901, PRO:HJD]
organism-sequence
PR:Q80YE4-3
serine/threonine-protein kinase LMTK1 isoform 3 (mouse)
mAATK/iso:3
"A serine/threonine-protein kinase LMTK1 isoform 3 that is encoded in the genome of mouse." [PMID:17651901, PRO:HJD]
Yes
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Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0030517
negative regulation of axon extension
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
GO:0046777
protein autophosphorylation
PR:Q80YE4-1
mAATK/iso:1
MGI_ref:3766666;
PMID:17651901
PR:Q80YE4-2
mAATK/iso:2
MGI_ref:3766666;
PMID:17651901
PR:Q80YE4-3
mAATK/iso:3
MGI_ref:3766666;
PMID:17651901
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515
protein binding
PR:000035696
mAATK/iso:2/Palm:1
MGI_ref:3820458;
PMID:18691334
PR:Q80YE4-2
mAATK/iso:2
MGI_ref:3820458;
PMID:18691334
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005783
endoplasmic reticulum
PR:Q80YE4-3
mAATK/iso:3
MGI_ref:3820458;
PMID:18691334
GO:0044295
axonal growth cone
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
GO:0048471
perinuclear region of cytoplasm
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
GO:0055037
recycling endosome
PR:000035696
mAATK/iso:2/Palm:1
MGI_ref:3820458;
PMID:18691334
PR:000035700
mAATK/iso:2/Phos:1
MGI_ref:5426470;
PMID:22573681
