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PRO ID
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| PRO name | histone acetyltransferase KAT6B/CREB-binding protein (human) |
| Synonyms | | PRO-Short-label: | EXACT: | hKAT6B/CBP(chimera) | | Other: | EXACT: | histone acetyltransferase MYST4/CREB-binding protein (human) | MORF/CBP (human) | MYST4/CBP chimera (human) |
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| Definition | "A chimeric protein that consists of part of the human KAT6B gene at the N terminus and part of the human CREBBP gene at the C-terminus. It includes the zinc fingers, 2 nuclear localization signals, the histone acetyltransferase (HAT) domain, a portion of the acidic domain of KAT6B and the zinc fingers, KIX domain, bromodomain and CREB-binding domain from CREBBP. This form is observed in some cases of acute myelogenous leukemia where chromosomal translocation occurs." [PMID:11157802] |
| PRO Category | organism-gene |
| Parent | PR:000003507 chimeric protein
PR:000029067 Homo sapiens protein
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| Taxon | NCBITaxon:9606 Homo sapiens |
Term Hierarchy
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