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Protein Ontology report - leukocyte granule-associated proteinase
PR:000003505 - http://purl.obolibrary.org/obo/PR_000003505
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003505   
  PRO nameleukocyte granule-associated proteinase 
  Definition"A trypsin that is a serine protease of the granules from mast cells, cytotoxic T lymphocytes and/or natural killer cells. Leukocyte granule-associated proteinase is a component of the immune system that protect higher organisms against viral infection and cellular transformation. Members of this class have features that are strongly conserved including: consensus sequences at their N-termini and around the three catalytic residues, activation from zymogenic forms, and conserved disulphide bridges." [PMID:11790262, PMID:7952649, PMID:8929545] 
  PRO Categoryfamily 
  ParentPR:000027795 trypsin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene10                                                  Organism-Gene 15                                        
         Sequence10                                                  Organism-Sequence 13                                        
         Modification23                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000003505 leukocyte granule-associated proteinase
GZMA/iso:1

gene


PR:000003472 granzyme K
GZMK

organism-gene


PR:O35205 granzyme K (mouse)
mGZMK

organism-gene


PR:P49863 granzyme K (human)
hGZMK

organism-sequence


PR:P49863-1 granzyme K isoform 1 (human)
hGZMK/iso:1

organism-modification


PR:000068076 granzyme K phosphorylated 1 (human)
hGZMK/Phos:1

organism-gene


PR:P49864 granzyme K (rat)
rGZMK

sequence


PR:000003473 granzyme K isoform 1
GZMK/iso:1

organism-sequence


PR:P49863-1 granzyme K isoform 1 (human)
hGZMK/iso:1

modification


PR:000018820 granzyme K proteolytic cleavage product
GZMK/ClvPrd

gene


PR:000003475 granzyme D
Gzmd

organism-gene


PR:P11033 granzyme D (mouse)
mGzmd

organism-sequence


PR:P11033-1 granzyme D isoform 1 (mouse)
mGzmd/iso:1

sequence


PR:000003476 granzyme D isoform 1
Gzmd/iso:1

organism-sequence


PR:P11033-1 granzyme D isoform 1 (mouse)
mGzmd/iso:1

modification


PR:000026635 granzyme D isoform 1, signal peptide removed form
Gzmd/iso:1/SigPep-

modification


PR:000018822 granzyme D, signal peptide removed form
Gzmd/SigPep-

modification


PR:000026635 granzyme D isoform 1, signal peptide removed form
Gzmd/iso:1/SigPep-

modification


PR:000018823 granzyme D proteolytic cleavage product
Gzmd/ClvPrd

gene


PR:000003478 granzyme G
Gzmg

organism-gene


PR:P13366 granzyme G (mouse)
mGzmg

organism-sequence


PR:P13366-1 granzyme G isoform 1 (mouse)
mGzmg/iso:1

sequence


PR:000003479 granzyme G isoform 1
Gzmg/iso:1

organism-sequence


PR:P13366-1 granzyme G isoform 1 (mouse)
mGzmg/iso:1

modification


PR:000026722 granzyme G isoform 1, signal peptide removed form
Gzmg/iso:1/SigPep-

modification


PR:000018825 granzyme G, signal peptide removed form
Gzmg/SigPep-

modification


PR:000026722 granzyme G isoform 1, signal peptide removed form
Gzmg/iso:1/SigPep-

modification


PR:000018826 granzyme G proteolytic cleavage product
Gzmg/ClvPrd

gene


PR:000003481 granzyme M
GZMM

organism-gene


PR:P51124 granzyme M (human)
hGZMM

organism-sequence


PR:P51124-1 granzyme M isoform 1 (human)
hGZMM/iso:1

organism-modification


PR:000076290 granzyme M, mature form (human)
hGZMM/mature

sequence


PR:000003482 granzyme M isoform 1
GZMM/iso:1

organism-sequence


PR:P51124-1 granzyme M isoform 1 (human)
hGZMM/iso:1

gene


PR:000003484 granzyme E
Gzme

organism-gene


PR:P08884 granzyme E (mouse)
mGzme

organism-sequence


PR:P08884-1 granzyme E isoform 1 (mouse)
mGzme/iso:1

sequence


PR:000003485 granzyme E isoform 1
Gzme/iso:1

organism-sequence


PR:P08884-1 granzyme E isoform 1 (mouse)
mGzme/iso:1

modification


PR:000026595 granzyme E isoform 1, signal peptide removed form
Gzme/iso:1/SigPep-

modification


PR:000018828 granzyme E, signal peptide removed form
Gzme/SigPep-

modification


PR:000026595 granzyme E isoform 1, signal peptide removed form
Gzme/iso:1/SigPep-

modification


PR:000018829 granzyme E proteolytic cleavage product
Gzme/ClvPrd

gene


PR:000003487 granzyme C
Gzmc

organism-gene


PR:P08882 granzyme C (mouse)
mGzmc

organism-sequence


PR:P08882-1 granzyme C isoform 1 (mouse)
mGzmc/iso:1

organism-gene


PR:Q9VAQ2 CG11843, isoform A (fruit fly)
fly-Gzmc

sequence


PR:000003488 granzyme C isoform 1
Gzmc/iso:1

organism-sequence


PR:P08882-1 granzyme C isoform 1 (mouse)
mGzmc/iso:1

modification


PR:000026721 granzyme C isoform 1, signal peptide removed form
Gzmc/iso:1/SigPep-

modification


PR:000018831 granzyme C, signal peptide removed form
Gzmc/SigPep-

modification


PR:000026721 granzyme C isoform 1, signal peptide removed form
Gzmc/iso:1/SigPep-

modification


PR:000018832 granzyme C proteolytic cleavage product
Gzmc/ClvPrd

gene


PR:000003490 granzyme H
GZMH

organism-gene


PR:A8WIQ2 uncharacterized protein, si:ch211-165b19.4 translation product (zebrafish)
z-GZMH

organism-gene


PR:P20718 granzyme H (human)
hGZMH

organism-sequence


PR:P20718-1 granzyme H isoform 1 (human)
hGZMH/iso:1

organism-sequence


PR:P20718-2 granzyme H isoform h2 (human)
hGZMH/iso:h2

organism-sequence


PR:P20718-3 granzyme H isoform h3 (human)
hGZMH/iso:h3

organism-modification


PR:000074268 granzyme H, mature form (human)
hGZMH/mature

sequence


PR:000003491 granzyme H isoform 1
GZMH/iso:1

organism-sequence


PR:P20718-1 granzyme H isoform 1 (human)
hGZMH/iso:1

modification


PR:000026717 granzyme H isoform 1, signal peptide removed form
GZMH/iso:1/SigPep-

modification


PR:000018834 granzyme H, signal peptide removed form
GZMH/SigPep-

modification


PR:000026717 granzyme H isoform 1, signal peptide removed form
GZMH/iso:1/SigPep-

organism-modification


PR:000074268 granzyme H, mature form (human)
hGZMH/mature

modification


PR:000018835 granzyme H proteolytic cleavage product
GZMH/ClvPrd

gene


PR:000003493 granzyme F
Gzmf

organism-gene


PR:P08883 granzyme F (mouse)
mGzmf

organism-sequence


PR:P08883-1 granzyme F isoform 1 (mouse)
mGzmf/iso:1

sequence


PR:000003494 granzyme F isoform 1
Gzmf/iso:1

organism-sequence


PR:P08883-1 granzyme F isoform 1 (mouse)
mGzmf/iso:1

modification


PR:000026685 granzyme F isoform 1, signal peptide removed form
Gzmf/iso:1/SigPep-

modification


PR:000018837 granzyme F, signal peptide removed form
Gzmf/SigPep-

modification


PR:000026685 granzyme F isoform 1, signal peptide removed form
Gzmf/iso:1/SigPep-

modification


PR:000018838 granzyme F proteolytic cleavage product
Gzmf/ClvPrd

gene


PR:000003499 granzyme B
GZMB

organism-gene


PR:P10144 granzyme B (human)
hGZMB

organism-sequence


PR:P10144-1 granzyme B isoform 1 (human)
hGZMB/iso:1

organism-modification


PR:000070174 granzyme B cysteinylated 1 (human)
hGZMB/Cyst:1

organism-modification


PR:000071760 granzyme B, mature form (human)
hGZMB/mature

organism-modification


PR:000083570 granzyme B cysteinylated 2 (human)
hGZMB/Cyst:2

sequence


PR:000003500 granzyme B isoform 1
GZMB/iso:1

organism-sequence


PR:P10144-1 granzyme B isoform 1 (human)
hGZMB/iso:1

organism-sequence


PR:P18291-1 granzyme B isoform 1 (rat)
rGZMB/iso:1

modification


PR:000026713 granzyme B isoform 1, signal peptide removed form
GZMB/iso:1/SigPep-

modification


PR:000026712 granzyme B, signal peptide removed form
GZMB/SigPep-

modification


PR:000026713 granzyme B isoform 1, signal peptide removed form
GZMB/iso:1/SigPep-

organism-modification


PR:000071760 granzyme B, mature form (human)
hGZMB/mature

gene


PR:000003502 granzyme A
GZMA

organism-gene


PR:P11032 granzyme A (mouse)
mGZMA

organism-sequence


PR:P11032-1 granzyme A isoform HF1 (mouse)
mGZMA/iso:HF1

organism-gene


PR:P12544 granzyme A (human)
hGZMA

sequence


PR:000003503 granzyme A isoform 1
GZMA/iso:1

organism-sequence


PR:P11032-1 granzyme A isoform HF1 (mouse)
mGZMA/iso:HF1

modification


PR:000026633 granzyme A isoform 1, signal peptide removed form
GZMA/iso:1/SigPep-

modification


PR:000026632 granzyme A, signal peptide removed form
GZMA/SigPep-

modification


PR:000026633 granzyme A isoform 1, signal peptide removed form
GZMA/iso:1/SigPep-