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Protein Ontology report - E3 SUMO-protein ligase PIAS2
PR:000003436 - http://purl.obolibrary.org/obo/PR_000003436
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003436   
  PRO nameE3 SUMO-protein ligase PIAS2 
  Synonyms
PRO-Short-label: EXACT:PIAS2
Gene-based: RELATED:PIASX
Other: EXACT:androgen receptor-interacting protein 3 | ARIP3 | miz1 | Msx-interacting zinc finger protein | PIAS-NY protein | protein inhibitor of activated STAT x | protein inhibitor of activated STAT2
RELATED:DAB2-interacting protein | DIP
  Definition"An E3 SUMO-protein ligase PIAS that is a translation product of the human PIAS2 gene or a 1:1 ortholog thereof." [MGI:1096566, PRO:HJD] 
  PRO Categorygene 
  ParentPR:000003444 E3 SUMO-protein ligase PIAS
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003436

E3 SUMO-protein ligase PIAS2

PIAS2


"An E3 SUMO-protein ligase PIAS that is a translation product of the human PIAS2 gene or a 1:1 ortholog thereof." [MGI:1096566, PRO:HJD]


organism-gene



PR:O75928

E3 SUMO-protein ligase PIAS2 (human)

hPIAS2


"An E3 SUMO-protein ligase PIAS2 that is encoded in the genome of human." [PRO:HJD, UniProtKB:O75928]


organism-sequence



PR:O75928-1

E3 SUMO-protein ligase PIAS2 isoform hPIAS2-beta (human)

hPIAS2/iso:hPIAS2-beta


"An E3 SUMO-protein ligase PIAS2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75928-1." [PRO:DNx, UniProtKB:O75928]


organism-sequence



PR:O75928-2

E3 SUMO-protein ligase PIAS2 isoform hPIAS2-alpha (human)

hPIAS2/iso:hPIAS2-alpha


"An E3 SUMO-protein ligase PIAS2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75928-2." [PRO:DNx, UniProtKB:O75928]


organism-sequence



PR:O75928-3

E3 SUMO-protein ligase PIAS2 isoform h3 (human)

hPIAS2/iso:h3


"An E3 SUMO-protein ligase PIAS2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75928-3." [PRO:DNx, UniProtKB:O75928]


organism-modification



PR:000076505

E3 SUMO-protein ligase PIAS2 cysteinylated 1 (human)

hPIAS2/Cyst:1


"An E3 SUMO-protein ligase PIAS2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-192 of the amino acid sequence represented by UniProtKB:O75928-1. Example: UniProtKB:O75928-1, Cys-192, MOD:00765." [IEDB_epitope:1039817, PRO:DNx]


organism-gene



PR:Q6AZ28

E3 SUMO-protein ligase PIAS2 (rat)

rPIAS2


"An E3 SUMO-protein ligase PIAS2 that is encoded in the genome of rat." [OMA:Q6AZ28, PRO:DNx]


organism-gene



PR:Q8C5D8

E3 SUMO-protein ligase PIAS2 (mouse)

mPIAS2


"An E3 SUMO-protein ligase PIAS2 that is encoded in the genome of mouse." [OMA:Q8C5D8, PRO:DNx]


organism-sequence



PR:Q8C5D8-1

E3 SUMO-protein ligase PIAS2 isoform 1 (mouse)

mPIAS2/iso:1


"An E3 SUMO-protein ligase PIAS2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:Q8C5D8-2

E3 SUMO-protein ligase PIAS2 isoform 2 (mouse)

mPIAS2/iso:2


"An E3 SUMO-protein ligase PIAS2 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:Q8C5D8-3

E3 SUMO-protein ligase PIAS2 isoform 3 (mouse)

mPIAS2/iso:3


"An E3 SUMO-protein ligase PIAS2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C5D8-3." [PMID:15489334, PRO:HJD, UniProtKB:Q8C5D8]


organism-sequence



PR:Q8C5D8-4

E3 SUMO-protein ligase PIAS2 isoform 4 (mouse)

mPIAS2/iso:4


"An E3 SUMO-protein ligase PIAS2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C5D8-4." [PMID:16141072, PRO:HJD, UniProtKB:Q8C5D8]


organism-sequence



PR:Q8C5D8-5

E3 SUMO-protein ligase PIAS2 isoform 5 (mouse)

mPIAS2/iso:5


"An E3 SUMO-protein ligase PIAS2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C5D8-5." [PMID:15489334, PRO:HJD, UniProtKB:Q8C5D8]


sequence



PR:000003437

E3 SUMO-protein ligase PIAS2 isoform 1

PIAS2/iso:1


"An E3 SUMO-protein ligase PIAS2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C5D8-1 or a 1:1 ortholog thereof." [PMID:17623776, PRO:HJD]


organism-sequence



PR:Q8C5D8-1

E3 SUMO-protein ligase PIAS2 isoform 1 (mouse)

mPIAS2/iso:1


"An E3 SUMO-protein ligase PIAS2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]

Yes

sequence



PR:000003442

E3 SUMO-protein ligase PIAS2 isoform 2

PIAS2/iso:2


"An E3 SUMO-protein ligase PIAS2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C5D8-2 or a 1:1 ortholog thereof." [PMID:11104669, PRO:HJD]


organism-sequence



PR:Q8C5D8-2

E3 SUMO-protein ligase PIAS2 isoform 2 (mouse)

mPIAS2/iso:2


"An E3 SUMO-protein ligase PIAS2 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8C5D8-1 mPIAS2/iso:1 acts_upstream_of_or_withinGO:0006351 DNA-templated transcription MGI_ref:894957; PMID:9256341
GO:0006357 regulation of transcription by RNA polymerase II MGI_ref:894957; PMID:9256341
GO:0016925 protein sumoylation PMID:15767674
GO:0045667 regulation of osteoblast differentiation MGI_ref:3723333; PMID:17623776
GO:0045893 positive regulation of DNA-templated transcription MGI_ref:3723333; PMID:17623776
enablesGO:0003677 DNA binding MGI_ref:894957; PMID:9256341
GO:0005515 protein binding with PR:P29037 mTBP PMID:16522640
GO:0005515 protein binding PMID:16522640
GO:0019789 SUMO transferase activity PMID:15767674
located_inGO:0005634 nucleus PMID:16522640
GO:0016604 nuclear body MGI_ref:3629292; PMID:16675951
PR:Q8C5D8-2 mPIAS2/iso:2 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:1929027; PMID:11104669
enablesGO:0005515 protein binding with PR:P98078-3 MGI_ref:1929027; PMID:11104669